BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 8820426)

  • 1. CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells.
    Gan LS; Moseley MA; Khosla B; Augustijns PF; Bradshaw TP; Hendren RW; Thakker DR
    Drug Metab Dispos; 1996 Mar; 24(3):344-9. PubMed ID: 8820426
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interplay between CYP3A-mediated metabolism and polarized efflux of terfenadine and its metabolites in intestinal epithelial Caco-2 (TC7) cell monolayers.
    Raeissi SD; Hidalgo IJ; Segura-Aguilar J; Artursson P
    Pharm Res; 1999 May; 16(5):625-32. PubMed ID: 10350002
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Influence of P-glycoprotein on the transport and metabolism of indinavir in Caco-2 cells expressing cytochrome P-450 3A4.
    Hochman JH; Chiba M; Nishime J; Yamazaki M; Lin JH
    J Pharmacol Exp Ther; 2000 Jan; 292(1):310-8. PubMed ID: 10604964
    [TBL] [Abstract][Full Text] [Related]  

  • 4. P-glycoprotein-mediated efflux of indinavir metabolites in Caco-2 cells expressing cytochrome P450 3A4.
    Hochman JH; Chiba M; Yamazaki M; Tang C; Lin JH
    J Pharmacol Exp Ther; 2001 Jul; 298(1):323-30. PubMed ID: 11408558
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components.
    Eagling VA; Profit L; Back DJ
    Br J Clin Pharmacol; 1999 Oct; 48(4):543-52. PubMed ID: 10583025
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence for a polarized efflux system in CACO-2 cells capable of modulating cyclosporin A transport.
    Augustijns PF; Bradshaw TP; Gan LS; Hendren RW; Thakker DR
    Biochem Biophys Res Commun; 1993 Dec; 197(2):360-5. PubMed ID: 7903526
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transport characteristics of ebastine and its metabolites across human intestinal epithelial Caco-2 cell monolayers.
    Imamura Y; Shimizu K; Yamashita F; Yamaoka K; Takakura Y; Hashida M
    Biol Pharm Bull; 2001 Aug; 24(8):930-4. PubMed ID: 11510488
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CYP3A4-transfected Caco-2 cells as a tool for understanding biochemical absorption barriers: studies with sirolimus and midazolam.
    Cummins CL; Jacobsen W; Christians U; Benet LZ
    J Pharmacol Exp Ther; 2004 Jan; 308(1):143-55. PubMed ID: 14569063
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.
    Cummins CL; Jacobsen W; Benet LZ
    J Pharmacol Exp Ther; 2002 Mar; 300(3):1036-45. PubMed ID: 11861813
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transport characteristics of peptidomimetics. Effect of the pyrrolinone bioisostere on transport across Caco-2 cell monolayers.
    Sudoh M; Pauletti GM; Yao W; Moser W; Yokoyama A; Pasternak A; Sprengeler PA; Smith AB; Hirschmann R; Borchardt RT
    Pharm Res; 1998 May; 15(5):719-25. PubMed ID: 9619780
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in caco-2 cells.
    Takanaga H; Ohnishi A; Matsuo H; Sawada Y
    Biol Pharm Bull; 1998 Oct; 21(10):1062-6. PubMed ID: 9821810
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies.
    Engman HA; Lennernäs H; Taipalensuu J; Otter C; Leidvik B; Artursson P
    J Pharm Sci; 2001 Nov; 90(11):1736-51. PubMed ID: 11745731
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a novel route of extraction of sirolimus in human small intestine: roles of metabolism and secretion.
    Paine MF; Leung LY; Lim HK; Liao K; Oganesian A; Zhang MY; Thummel KE; Watkins PB
    J Pharmacol Exp Ther; 2002 Apr; 301(1):174-86. PubMed ID: 11907172
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Carrier mechanisms involved in the transepithelial transport of bis(POM)-PMEA and its metabolites across Caco-2 monolayers.
    Annaert P; Van Gelder J; Naesens L; De Clercq E; Van den Mooter G; Kinget R; Augustijns P
    Pharm Res; 1998 Aug; 15(8):1168-73. PubMed ID: 9706045
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein.
    Brimer C; Dalton JT; Zhu Z; Schuetz J; Yasuda K; Vanin E; Relling MV; Lu Y; Schuetz EG
    Pharm Res; 2000 Jul; 17(7):803-10. PubMed ID: 10990198
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of the efflux transporter(s) responsible for restricting intestinal mucosa permeation of the coumarinic acid-based cyclic prodrug of the opioid peptide DADLE.
    Tang F; Borchardt RT
    Pharm Res; 2002 Jun; 19(6):787-93. PubMed ID: 12134948
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overlapping substrate specificities of cytochrome P450 3A and P-glycoprotein for a novel cysteine protease inhibitor.
    Zhang Y; Guo X; Lin ET; Benet LZ
    Drug Metab Dispos; 1998 Apr; 26(4):360-6. PubMed ID: 9531525
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Atorvastatin transport in the Caco-2 cell model: contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter.
    Wu X; Whitfield LR; Stewart BH
    Pharm Res; 2000 Feb; 17(2):209-15. PubMed ID: 10751037
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor.
    Chiba M; Hensleigh M; Nishime JA; Balani SK; Lin JH
    Drug Metab Dispos; 1996 Mar; 24(3):307-14. PubMed ID: 8820421
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New insights into drug absorption: studies with sirolimus.
    Paine MF; Leung LY; Watkins PB
    Ther Drug Monit; 2004 Oct; 26(5):463-7. PubMed ID: 15385826
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.