BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 8824261)

  • 1. Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity.
    Engh RA; Girod A; Kinzel V; Huber R; Bossemeyer D
    J Biol Chem; 1996 Oct; 271(42):26157-64. PubMed ID: 8824261
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluation of docking strategies for virtual screening of compound databases: cAMP-dependent serine/threonine kinase as an example.
    Godden JW; Stahura F; Bajorath J
    J Mol Graph Model; 1998 Jun; 16(3):139-43, 165. PubMed ID: 10434253
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The structure of dimeric ROCK I reveals the mechanism for ligand selectivity.
    Jacobs M; Hayakawa K; Swenson L; Bellon S; Fleming M; Taslimi P; Doran J
    J Biol Chem; 2006 Jan; 281(1):260-8. PubMed ID: 16249185
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity.
    Breitenlechner C; Gassel M; Hidaka H; Kinzel V; Huber R; Engh RA; Bossemeyer D
    Structure; 2003 Dec; 11(12):1595-607. PubMed ID: 14656443
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibitors of cGMP-dependent protein kinase block senescence induced by inactivation of T antigen in SV40-transformed immortal human fibroblasts.
    Fujii M; Ide T; Wadhwa R; Tahara H; Kaul SC; Mitsui Y; Ogata T; Oishi M; Ayusawa D
    Oncogene; 1995 Aug; 11(4):627-34. PubMed ID: 7651725
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis for selectivity of the isoquinoline sulfonamide family of protein kinase inhibitors.
    Xu RM; Carmel G; Kuret J; Cheng X
    Proc Natl Acad Sci U S A; 1996 Jun; 93(13):6308-13. PubMed ID: 8692811
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of cytotoxic T lymphocyte-mediated lysis and cellular proliferation by isoquinoline sulfonamide protein kinase inhibitors. Evidence for the involvement of protein kinase C in lymphocyte function.
    Juszczak RJ; Russell JH
    J Biol Chem; 1989 Jan; 264(2):810-5. PubMed ID: 2783420
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein kinase inhibitors.
    Hidaka H; Kobayashi R
    Essays Biochem; 1994; 28():73-97. PubMed ID: 7925321
    [No Abstract]   [Full Text] [Related]  

  • 9. Molecular modeling of G-protein coupled receptor kinase 2: docking and biochemical evaluation of inhibitors.
    Kassack MU; Högger P; Gschwend DA; Kameyama K; Haga T; Graul RC; Sadée W
    AAPS PharmSci; 2000; 2(1):E2. PubMed ID: 11741218
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine.
    Narayana N; Cox S; Shaltiel S; Taylor SS; Xuong N
    Biochemistry; 1997 Apr; 36(15):4438-48. PubMed ID: 9109651
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of PKA inhibitors, H-compounds, on epithelial Na+ channels via PKA-independent mechanisms.
    Niisato N; Ito Y; Marunaka Y
    Life Sci; 1999; 65(10):PL109-14. PubMed ID: 10499877
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants.
    Breitenlechner CB; Friebe WG; Brunet E; Werner G; Graul K; Thomas U; Künkele KP; Schäfer W; Gassel M; Bossemeyer D; Huber R; Engh RA; Masjost B
    J Med Chem; 2005 Jan; 48(1):163-70. PubMed ID: 15634010
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives.
    Hagiwara M; Inagaki M; Watanabe M; Ito M; Onoda K; Tanaka T; Hidaka H
    Mol Pharmacol; 1987 Jul; 32(1):7-12. PubMed ID: 2955213
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The contribution of PKA to the excitatory mechanism of adenosine in guinea pig superior colliculus slices.
    Hirai H; Ikeuchi Y; Okada Y
    Neurosci Lett; 1994 Nov; 182(1):33-6. PubMed ID: 7891883
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential regulation of phospholipase A2 (PLA2)-dependent Ca2+ signaling in smooth muscle by cAMP- and cGMP-dependent protein kinases. Inhibitory phosphorylation of PLA2 by cyclic nucleotide-dependent protein kinases.
    Murthy KS; Makhlouf GM
    J Biol Chem; 1998 Dec; 273(51):34519-26. PubMed ID: 9852121
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of Chlamydomonas flagellar dynein by an axonemal protein kinase.
    Howard DR; Habermacher G; Glass DB; Smith EF; Sale WS
    J Cell Biol; 1994 Dec; 127(6 Pt 1):1683-92. PubMed ID: 7798320
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-based design of isoquinoline-5-sulfonamide inhibitors of protein kinase B.
    Collins I; Caldwell J; Fonseca T; Donald A; Bavetsias V; Hunter LJ; Garrett MD; Rowlands MG; Aherne GW; Davies TG; Berdini V; Woodhead SJ; Davis D; Seavers LC; Wyatt PG; Workman P; McDonald E
    Bioorg Med Chem; 2006 Feb; 14(4):1255-73. PubMed ID: 16249095
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein kinase A inhibitors enhance radiation-induced apoptosis.
    Findik D; Song Q; Hidaka H; Lavin M
    J Cell Biochem; 1995 Jan; 57(1):12-21. PubMed ID: 7536751
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of protein kinase inhibitors on radiation-induced WAF1 accumulation in human cultured melanoma cells.
    Fujino M; Ohnishi K; Asahi M; Wang X; Takahashi A; Ohnishi T
    Br J Dermatol; 1999 Oct; 141(4):652-7. PubMed ID: 10583112
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase.
    Narayana N; Diller TC; Koide K; Bunnage ME; Nicolaou KC; Brunton LL; Xuong NH; Ten Eyck LF; Taylor SS
    Biochemistry; 1999 Feb; 38(8):2367-76. PubMed ID: 10029530
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.