BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

98 related articles for article (PubMed ID: 8831759)

  • 1. 1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency.
    Boehm JC; Smietana JM; Sorenson ME; Garigipati RS; Gallagher TF; Sheldrake PL; Bradbeer J; Badger AM; Laydon JT; Lee JC; Hillegass LM; Griswold DE; Breton JJ; Chabot-Fletcher MC; Adams JL
    J Med Chem; 1996 Sep; 39(20):3929-37. PubMed ID: 8831759
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of novel anti-inflammatory compounds on healing of acetic acid-induced gastric ulcer in rats.
    Lesch CA; Gilbertsen RB; Song Y; Dyer RD; Schrier D; Kraus ER; Sanchez B; Guglietta A
    J Pharmacol Exp Ther; 1998 Oct; 287(1):301-6. PubMed ID: 9765350
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors.
    Hong SH; Avis I; Vos MD; Martínez A; Treston AM; Mulshine JL
    Cancer Res; 1999 May; 59(9):2223-8. PubMed ID: 10232612
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
    Riendeau D; Percival MD; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Falgueyret JP; Ford-Hutchinson AW; Gordon R; Greig G; Gresser M; Guay J; Kargman S; Léger S; Mancini JA; O'Neill G; Ouellet M; Rodger IW; Thérien M; Wang Z; Webb JK; Wong E; Chan CC
    Br J Pharmacol; 1997 May; 121(1):105-17. PubMed ID: 9146894
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-alpha production.
    Chen CS; Tan CM; Huang CH; Chang LC; Wang JP; Cheng FC; Chern JW
    Bioorg Med Chem; 2010 Jan; 18(2):597-604. PubMed ID: 20056549
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dibenzoxepinone hydroxylamines and hydroxamic acids: dual inhibitors of cyclooxygenase and 5-lipoxygenase with potent topical antiinflammatory activity.
    Hamer RR; Tegeler JJ; Kurtz ES; Allen RC; Bailey SC; Elliott ME; Hellyer L; Helsley GC; Przekop P; Freed BS; White J; Martin LL
    J Med Chem; 1996 Jan; 39(1):246-52. PubMed ID: 8568814
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Inhibition of the arachidonic acid cascade by aza-2-aryl-1,4-naphthoquinone derivatives].
    Richwien A; Wurm G
    Pharmazie; 2004 Dec; 59(12):906-12. PubMed ID: 15638076
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Covalent modification of cyclooxygenase-2 (COX-2) by 2-acetoxyphenyl alkyl sulfides, a new class of selective COX-2 inactivators.
    Kalgutkar AS; Kozak KR; Crews BC; Hochgesang GP; Marnett LJ
    J Med Chem; 1998 Nov; 41(24):4800-18. PubMed ID: 9822550
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes.
    Laufer SA; Wagner GK; Kotschenreuther DA; Albrecht W
    J Med Chem; 2003 Jul; 46(15):3230-44. PubMed ID: 12852754
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents.
    Khanna IK; Weier RM; Yu Y; Xu XD; Koszyk FJ; Collins PW; Koboldt CM; Veenhuizen AW; Perkins WE; Casler JJ; Masferrer JL; Zhang YY; Gregory SA; Seibert K; Isakson PC
    J Med Chem; 1997 May; 40(11):1634-47. PubMed ID: 9171873
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of novel and potent small-molecule inhibitors of NO and cytokine production as antisepsis agents: synthesis and biological activity of alkyl 6-(N-substituted sulfamoyl)cyclohex-1-ene-1-carboxylate.
    Yamada M; Ichikawa T; Ii M; Sunamoto M; Itoh K; Tamura N; Kitazaki T
    J Med Chem; 2005 Nov; 48(23):7457-67. PubMed ID: 16279805
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibitors of tumor progression loci-2 (Tpl2) kinase and tumor necrosis factor alpha (TNF-alpha) production: selectivity and in vivo antiinflammatory activity of novel 8-substituted-4-anilino-6-aminoquinoline-3-carbonitriles.
    Green N; Hu Y; Janz K; Li HQ; Kaila N; Guler S; Thomason J; Joseph-McCarthy D; Tam SY; Hotchandani R; Wu J; Huang A; Wang Q; Leung L; Pelker J; Marusic S; Hsu S; Telliez JB; Hall JP; Cuozzo JW; Lin LL
    J Med Chem; 2007 Sep; 50(19):4728-45. PubMed ID: 17715908
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of FR133605, a novel cytokine suppressive agent, on bone and cartilage destruction in adjuvant arthritic rats.
    Yamamoto N; Sakai F; Yamazaki H; Kawai Y; Nakahara K; Okuhara M
    J Rheumatol; 1996 Oct; 23(10):1778-83. PubMed ID: 8895158
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Influence of 2-aryl-3-halogen/3-hydroxy-1,4-naphthoquinones with salicylic and cinnamic acid partial structures on the arachidonic acid cascade].
    Richwien A; Wurm G
    Pharmazie; 2004 Mar; 59(3):163-9. PubMed ID: 15074584
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
    Song Y; Connor DT; Doubleday R; Sorenson RJ; Sercel AD; Unangst PC; Roth BD; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
    J Med Chem; 1999 Apr; 42(7):1151-60. PubMed ID: 10197959
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.
    Chan CC; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Ford-Hutchinson AW; Forrest MJ; Gauthier JY; Gordon R; Gresser M; Guay J; Kargman S; Kennedy B; Leblanc Y; Leger S; Mancini J; O'Neill GP; Ouellet M; Patrick D; Percival MD; Perrier H; Prasit P; Rodger I
    J Pharmacol Exp Ther; 1999 Aug; 290(2):551-60. PubMed ID: 10411562
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of tanshinone I isolated from Salvia miltiorrhiza bunge on arachidonic acid metabolism and in vivo inflammatory responses.
    Kim SY; Moon TC; Chang HW; Son KH; Kang SS; Kim HP
    Phytother Res; 2002 Nov; 16(7):616-20. PubMed ID: 12410540
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparison of in vitro-activity of commonly used topical glucocorticoids on cytokine- and phospholipase inhibition.
    Juergens UR; Jäger F; Darlath W; Stöber M; Vetter H; Gillissen A
    Eur J Med Res; 2004 Aug; 9(8):383-90. PubMed ID: 15337628
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New cyclooxygenase-2/5-lipoxygenase inhibitors. 3. 7-tert-butyl-2, 3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: variations at the 5 position.
    Janusz JM; Young PA; Ridgeway JM; Scherz MW; Enzweiler K; Wu LI; Gan L; Chen J; Kellstein DE; Green SA; Tulich JL; Rosario-Jansen T; Magrisso IJ; Wehmeyer KR; Kuhlenbeck DL; Eichhold TH; Dobson RL
    J Med Chem; 1998 Aug; 41(18):3515-29. PubMed ID: 9719605
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibitory effects of black tea theaflavin derivatives on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and arachidonic acid metabolism in mouse ears.
    Huang MT; Liu Y; Ramji D; Lo CY; Ghai G; Dushenkov S; Ho CT
    Mol Nutr Food Res; 2006 Feb; 50(2):115-22. PubMed ID: 16404705
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.