294 related articles for article (PubMed ID: 8837617)
1. The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.
Lemere CA; Lopera F; Kosik KS; Lendon CL; Ossa J; Saido TC; Yamaguchi H; Ruiz A; Martinez A; Madrigal L; Hincapie L; Arango JC; Anthony DC; Koo EH; Goate AM; Selkoe DJ; Arango JC
Nat Med; 1996 Oct; 2(10):1146-50. PubMed ID: 8837617
[TBL] [Abstract][Full Text] [Related]
2. The impact of different presenilin 1 andpresenilin 2 mutations on amyloid deposition, neurofibrillary changes and neuronal loss in the familial Alzheimer's disease brain: evidence for other phenotype-modifying factors.
Gómez-Isla T; Growdon WB; McNamara MJ; Nochlin D; Bird TD; Arango JC; Lopera F; Kosik KS; Lantos PL; Cairns NJ; Hyman BT
Brain; 1999 Sep; 122 ( Pt 9)():1709-19. PubMed ID: 10468510
[TBL] [Abstract][Full Text] [Related]
3. Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease.
Sepulveda-Falla D; Matschke J; Bernreuther C; Hagel C; Puig B; Villegas A; Garcia G; Zea J; Gomez-Mancilla B; Ferrer I; Lopera F; Glatzel M
Brain Pathol; 2011 Jul; 21(4):452-63. PubMed ID: 21159009
[TBL] [Abstract][Full Text] [Related]
4. Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis.
Sepulveda-Falla D; Barrera-Ocampo A; Hagel C; Korwitz A; Vinueza-Veloz MF; Zhou K; Schonewille M; Zhou H; Velazquez-Perez L; Rodriguez-Labrada R; Villegas A; Ferrer I; Lopera F; Langer T; De Zeeuw CI; Glatzel M
J Clin Invest; 2014 Apr; 124(4):1552-67. PubMed ID: 24569455
[TBL] [Abstract][Full Text] [Related]
5. Novel presenilin-1 mutation with widespread cortical amyloid deposition but limited cerebral amyloid angiopathy.
Yasuda M; Maeda S; Kawamata T; Tamaoka A; Yamamoto Y; Kuroda S; Maeda K; Tanaka C
J Neurol Neurosurg Psychiatry; 2000 Feb; 68(2):220-3. PubMed ID: 10644793
[TBL] [Abstract][Full Text] [Related]
6. Cell-type-specific enhancement of amyloid-beta deposition in a novel presenilin-1 mutation (P117L).
Wegiel J; Wisniewski HM; Kuchna I; Tarnawski M; Badmajew E; Popovitch E; Kulczycki J; Dowjat WK; Wisniewski T
J Neuropathol Exp Neurol; 1998 Sep; 57(9):831-8. PubMed ID: 9737546
[TBL] [Abstract][Full Text] [Related]
7. A pathogenic presenilin-1 deletion causes abberrant Abeta 42 production in the absence of congophilic amyloid plaques.
Steiner H; Revesz T; Neumann M; Romig H; Grim MG; Pesold B; Kretzschmar HA; Hardy J; Holton JL; Baumeister R; Houlden H; Haass C
J Biol Chem; 2001 Mar; 276(10):7233-9. PubMed ID: 11084029
[TBL] [Abstract][Full Text] [Related]
8. Cytoskeletal alterations differentiate presenilin-1 and sporadic Alzheimer's disease.
Woodhouse A; Shepherd CE; Sokolova A; Carroll VL; King AE; Halliday GM; Dickson TC; Vickers JC
Acta Neuropathol; 2009 Jan; 117(1):19-29. PubMed ID: 19015863
[TBL] [Abstract][Full Text] [Related]
9. A novel highly pathogenic Alzheimer presenilin-1 mutation in codon 117 (Pro117Ser): Comparison of clinical, neuropathological and cell culture phenotypes of Pro117Leu and Pro117Ser mutations.
Dowjat WK; Kuchna I; Wisniewski T; Wegiel J
J Alzheimers Dis; 2004 Feb; 6(1):31-43. PubMed ID: 15004326
[TBL] [Abstract][Full Text] [Related]
10. [Neuropathological findings in early-onset Alzheimer's disease (E280a-PS1 mutation)].
Duque-Castaño A; Roldán MI; Arango-Viana JC; Arcos-Burgos M; Cubillo H; Lopera F
Rev Neurol; 1999 Jul 1-15; 29(1):1-6. PubMed ID: 10528300
[TBL] [Abstract][Full Text] [Related]
11. Adverse effect of a presenilin-1 mutation in microglia results in enhanced nitric oxide and inflammatory cytokine responses to immune challenge in the brain.
Lee J; Chan SL; Mattson MP
Neuromolecular Med; 2002; 2(1):29-45. PubMed ID: 12230303
[TBL] [Abstract][Full Text] [Related]
12. Protein markers for Alzheimer disease in the frontal cortex and cerebellum.
Verdile G; Gnjec A; Miklossy J; Fonte J; Veurink G; Bates K; Kakulas B; Mehta PD; Milward EA; Tan N; Lareu R; Lim D; Dharmarajan A; Martins RN
Neurology; 2004 Oct; 63(8):1385-92. PubMed ID: 15505153
[TBL] [Abstract][Full Text] [Related]
13. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease.
Scheuner D; Eckman C; Jensen M; Song X; Citron M; Suzuki N; Bird TD; Hardy J; Hutton M; Kukull W; Larson E; Levy-Lahad E; Viitanen M; Peskind E; Poorkaj P; Schellenberg G; Tanzi R; Wasco W; Lannfelt L; Selkoe D; Younkin S
Nat Med; 1996 Aug; 2(8):864-70. PubMed ID: 8705854
[TBL] [Abstract][Full Text] [Related]
14. Formation of tau inclusions in knock-in mice with familial Alzheimer disease (FAD) mutation of presenilin 1 (PS1).
Tanemura K; Chui DH; Fukuda T; Murayama M; Park JM; Akagi T; Tatebayashi Y; Miyasaka T; Kimura T; Hashikawa T; Nakano Y; Kudo T; Takeda M; Takashima A
J Biol Chem; 2006 Feb; 281(8):5037-41. PubMed ID: 16377636
[TBL] [Abstract][Full Text] [Related]
15. Enhancement of amyloid beta 42 secretion by 28 different presenilin 1 mutations of familial Alzheimer's disease.
Murayama O; Tomita T; Nihonmatsu N; Murayama M; Sun X; Honda T; Iwatsubo T; Takashima A
Neurosci Lett; 1999 Apr; 265(1):61-3. PubMed ID: 10327206
[TBL] [Abstract][Full Text] [Related]
16. CA1 hippocampal neuronal loss in familial Alzheimer's disease presenilin-1 E280A mutation is related to epilepsy.
Velez-Pardo C; Arellano JI; Cardona-Gomez P; Jimenez Del Rio M; Lopera F; De Felipe J
Epilepsia; 2004 Jul; 45(7):751-6. PubMed ID: 15230697
[TBL] [Abstract][Full Text] [Related]
17. A novel presenilin-1 mutation: increased beta-amyloid and neurofibrillary changes.
Gómez-Isla T; Wasco W; Pettingell WP; Gurubhagavatula S; Schmidt SD; Jondro PD; McNamara M; Rodes LA; DiBlasi T; Growdon WB; Seubert P; Schenk D; Growdon JH; Hyman BT; Tanzi RE
Ann Neurol; 1997 Jun; 41(6):809-13. PubMed ID: 9189043
[TBL] [Abstract][Full Text] [Related]
18. Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease.
Mathews PM; Cataldo AM; Kao BH; Rudnicki AG; Qin X; Yang JL; Jiang Y; Picciano M; Hulette C; Lippa CF; Bird TD; Nochlin D; Walter J; Haass C; Lévesque L; Fraser PE; Andreadis A; Nixon RA
Mol Med; 2000 Oct; 6(10):878-91. PubMed ID: 11126202
[TBL] [Abstract][Full Text] [Related]
19. Increased A beta 42(43)-plaque deposition in early-onset familial Alzheimer's disease brains with the deletion of exon 9 and the missense point mutation (H163R) in the PS-1 gene.
Ishii K; Ii K; Hasegawa T; Shoji S; Doi A; Mori H
Neurosci Lett; 1997 May; 228(1):17-20. PubMed ID: 9197277
[TBL] [Abstract][Full Text] [Related]
20. The gene defects responsible for familial Alzheimer's disease.
Tanzi RE; Kovacs DM; Kim TW; Moir RD; Guenette SY; Wasco W
Neurobiol Dis; 1996; 3(3):159-68. PubMed ID: 8980016
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
