710 related articles for article (PubMed ID: 8839054)
1. Bioactivation of estrone and its catechol metabolites to quinoid-glutathione conjugates in rat liver microsomes.
Iverson SL; Shen L; Anlar N; Bolton JL
Chem Res Toxicol; 1996 Mar; 9(2):492-9. PubMed ID: 8839054
[TBL] [Abstract][Full Text] [Related]
2. p-Quinone methides are the major decomposition products of catechol estrogen o-quinones.
Bolton JL; Shen L
Carcinogenesis; 1996 May; 17(5):925-9. PubMed ID: 8640939
[TBL] [Abstract][Full Text] [Related]
3. The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone.
Zhang F; Chen Y; Pisha E; Shen L; Xiong Y; van Breemen RB; Bolton JL
Chem Res Toxicol; 1999 Feb; 12(2):204-13. PubMed ID: 10027800
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of glutathione S-transferase activity by the quinoid metabolites of equine estrogens.
Chang M; Zhang F; Shen L; Pauss N; Alam I; van Breemen RB; Blond SY; Bolton JL
Chem Res Toxicol; 1998 Jul; 11(7):758-65. PubMed ID: 9671538
[TBL] [Abstract][Full Text] [Related]
5. NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.
Zhao SX; Dalvie DK; Kelly JM; Soglia JR; Frederick KS; Smith EB; Obach RS; Kalgutkar AS
Chem Res Toxicol; 2007 Nov; 20(11):1649-57. PubMed ID: 17907785
[TBL] [Abstract][Full Text] [Related]
6. Covalent binding of catechol estrogens to glutathione catalyzed by horseradish peroxidase, lactoperoxidase, or rat liver microsomes.
Cao K; Devanesan PD; Ramanathan R; Gross ML; Rogan EG; Cavalieri EL
Chem Res Toxicol; 1998 Aug; 11(8):917-24. PubMed ID: 9705754
[TBL] [Abstract][Full Text] [Related]
7. The influence of the p-alkyl substituent on the isomerization of o-quinones to p-quinone methides: potential bioactivation mechanism for catechols.
Iverson SL; Hu LQ; Vukomanovic V; Bolton JL
Chem Res Toxicol; 1995 Jun; 8(4):537-44. PubMed ID: 7548733
[TBL] [Abstract][Full Text] [Related]
8. Bioactivation of the selective estrogen receptor modulator acolbifene to quinone methides.
Liu J; Liu H; van Breemen RB; Thatcher GR; Bolton JL
Chem Res Toxicol; 2005 Feb; 18(2):174-82. PubMed ID: 15720121
[TBL] [Abstract][Full Text] [Related]
9. Spectroscopic characterization of the 4-hydroxy catechol estrogen quinones-derived GSH and N-acetylated Cys conjugates.
Jankowiak R; Markushin Y; Cavalieri EL; Small GJ
Chem Res Toxicol; 2003 Mar; 16(3):304-11. PubMed ID: 12641430
[TBL] [Abstract][Full Text] [Related]
10. Cytochrome P450 isoforms catalyze formation of catechol estrogen quinones that react with DNA.
Zhang Y; Gaikwad NW; Olson K; Zahid M; Cavalieri EL; Rogan EG
Metabolism; 2007 Jul; 56(7):887-94. PubMed ID: 17570247
[TBL] [Abstract][Full Text] [Related]
11. Bioactivation of tamoxifen to metabolite E quinone methide: reaction with glutathione and DNA.
Fan PW; Bolton JL
Drug Metab Dispos; 2001 Jun; 29(6):891-6. PubMed ID: 11353759
[TBL] [Abstract][Full Text] [Related]
12. Mechanism of isomerization of 4-propyl-o-quinone to its tautomeric p-quinone methide.
Bolton JL; Wu HM; Hu LQ
Chem Res Toxicol; 1996; 9(1):109-113. PubMed ID: 8924578
[TBL] [Abstract][Full Text] [Related]
13. 17 beta-estradiol metabolism by hamster hepatic microsomes: comparison of catechol estrogen O-methylation with catechol estrogen oxidation and glutathione conjugation.
Butterworth M; Lau SS; Monks TJ
Chem Res Toxicol; 1996 Jun; 9(4):793-9. PubMed ID: 8831825
[TBL] [Abstract][Full Text] [Related]
14. Bioactivation of phencyclidine in rat and human liver microsomes and recombinant P450 2B enzymes: evidence for the formation of a novel quinone methide intermediate.
Driscoll JP; Kornecki K; Wolkowski JP; Chupak L; Kalgutkar AS; O'Donnell JP
Chem Res Toxicol; 2007 Oct; 20(10):1488-97. PubMed ID: 17892269
[TBL] [Abstract][Full Text] [Related]
15. Evidence that 4-allyl-o-quinones spontaneously rearrange to their more electrophilic quinone methides: potential bioactivation mechanism for the hepatocarcinogen safrole.
Bolton JL; Acay NM; Vukomanovic V
Chem Res Toxicol; 1994; 7(3):443-50. PubMed ID: 8075378
[TBL] [Abstract][Full Text] [Related]
16. The influence of 4-alkyl substituents on the formation and reactivity of 2-methoxy-quinone methides: evidence that extended pi-conjugation dramatically stabilizes the quinone methide formed from eugenol.
Bolton JL; Comeau E; Vukomanovic V
Chem Biol Interact; 1995 Apr; 95(3):279-90. PubMed ID: 7728898
[TBL] [Abstract][Full Text] [Related]
17. Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment.
Hissink AM; Oudshoorn MJ; Van Ommen B; Haenen GR; Van Bladeren PJ
Chem Res Toxicol; 1996 Dec; 9(8):1249-56. PubMed ID: 8951226
[TBL] [Abstract][Full Text] [Related]
18. Quenching of quercetin quinone/quinone methides by different thiolate scavengers: stability and reversibility of conjugate formation.
Awad HM; Boersma MG; Boeren S; Van Bladeren PJ; Vervoort J; Rietjens IM
Chem Res Toxicol; 2003 Jul; 16(7):822-31. PubMed ID: 12870884
[TBL] [Abstract][Full Text] [Related]
19. Development and evaluation of an electrochemical method for studying reactive phase-I metabolites: correlation to in vitro drug metabolism.
Madsen KG; Olsen J; Skonberg C; Hansen SH; Jurva U
Chem Res Toxicol; 2007 May; 20(5):821-31. PubMed ID: 17447796
[TBL] [Abstract][Full Text] [Related]
20. Oxo substituents markedly alter the phase II metabolism of alpha-hydroxybutenylbenzenes: models probing the bioactivation mechanisms of tamoxifen.
Ramakrishna KV; Fan PW; Boyer CS; Dalvie D; Bolton JL
Chem Res Toxicol; 1997 Aug; 10(8):887-94. PubMed ID: 9282838
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
