These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 8840988)

  • 1. Lack of glutathione conjugation of melphalan in the isolated in situ liver perfusion in humans.
    Vahrmeijer AL; Snel CA; Steenvoorden DP; Beijnen JH; Pang KS; Schutrups J; Tirona R; Keizer HJ; van Dierendonck JH; van de Velde CJ; Mulder GJ
    Cancer Res; 1996 Oct; 56(20):4709-14. PubMed ID: 8840988
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The fate of diastereomeric glutathione conjugates of alpha-bromoisovalerylurea in blood in the rat in vivo and in the perfused liver. Stereoselectivity in biliary and urinary excretion.
    Polhuijs M; Meijer DK; Mulder GJ
    J Pharmacol Exp Ther; 1991 Feb; 256(2):458-61. PubMed ID: 1993989
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolism of melphalan by rat liver microsomal glutathione S-transferase.
    Zhang J; Ye Z; Lou Y
    Chem Biol Interact; 2005 Apr; 152(2-3):101-6. PubMed ID: 15840383
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In-transit melanoma: the role of alkylating-agent resistance in regional therapy.
    Grubbs EG; Abdel-Wahab O; Cheng TY; Abdel-Wahab Z; Peterson B; Pruitt SK; Colvin OM; Friedman HS; Tyler DS
    J Am Coll Surg; 2004 Sep; 199(3):419-27. PubMed ID: 15325612
    [TBL] [Abstract][Full Text] [Related]  

  • 5. alpha-Bromoisovalerylurea as model substrate for studies on pharmacokinetics of glutathione conjugation in the rat. II. Pharmacokinetics and stereoselectivity of metabolism and excretion in vivo and in the perfused liver.
    te Koppele JM; Dogterom P; Vermeulen NP; Meijer DK; van der Gen A; Mulder GJ
    J Pharmacol Exp Ther; 1986 Dec; 239(3):905-14. PubMed ID: 3795049
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conjugation of glutathione with a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, catalyzed by rat hepatic glutathione-S-transferases.
    Tang W; Borel AG; Abbott FS
    Drug Metab Dispos; 1996 Apr; 24(4):436-46. PubMed ID: 8801059
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reduced liver uptake of arterially infused melphalan during retrograde rat liver perfusion with unaffected liver tumor uptake.
    Rothbarth J; Sparidans RW; Beijnen JH; Schultze-Kool LJ; Putter H; van de Velde CJ; Mulder GJ
    J Pharmacol Exp Ther; 2002 Nov; 303(2):736-40. PubMed ID: 12388659
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stereoselectivity of glutathione conjugation: blood elimination of alpha-bromoisovalerylurea enantiomers and biliary excretion of the conjugates in unanesthetized normal or congenitally jaundiced rats.
    Polhuijs M; Kuipers F; Vonk RJ; Mulder GJ
    J Pharmacol Exp Ther; 1989 Jun; 249(3):874-8. PubMed ID: 2732949
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bimolecular glutathione conjugation kinetics of ethacrynic acid in rat liver: in vitro and perfusion studies.
    Tirona RG; Pang KS
    J Pharmacol Exp Ther; 1999 Sep; 290(3):1230-41. PubMed ID: 10454499
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glutathione conjugation and pharmacokinetics of 2-bromo-3-phenylpropionic acid in vitro and in the rat in vivo.
    Snel CA; Mahadevan S; Polhuijs M; Mulder GJ
    Chirality; 1992; 4(7):407-14. PubMed ID: 1361150
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hepatic artery infusion of high-dose melphalan at reduced flow during isolated hepatic perfusion for the treatment of colorectal metastases confined to the liver: a clinical and pharmacologic evaluation.
    van Iersel LB; Verlaan MR; Vahrmeijer AL; van Persijn van Meerten EL; Tijl FG; Sparidans RW; Gelderblom H; Kuppen PJ; Tollenaar RA; van de Velde CJ
    Eur J Surg Oncol; 2007 Sep; 33(7):874-81. PubMed ID: 17400422
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification in rat bile of glutathione conjugates of fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether, a nephrotoxic degradate of the anesthetic agent sevoflurane.
    Jin L; Davis MR; Kharasch ED; Doss GA; Baillie TA
    Chem Res Toxicol; 1996 Mar; 9(2):555-61. PubMed ID: 8839062
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Increased local cytostatic drug exposure by isolated hepatic perfusion: a phase I clinical and pharmacologic evaluation of treatment with high dose melphalan in patients with colorectal cancer confined to the liver.
    Vahrmeijer AL; van Dierendonck JH; Keizer HJ; Beijnen JH; Tollenaar RA; Pijl ME; Marinelli A; Kuppen PJ; van Bockel JH; Mulder GJ; van de Velde CJ
    Br J Cancer; 2000 May; 82(9):1539-46. PubMed ID: 10789721
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The metabolism and excretion of styrene oxide-glutathione conjugates in the rat and by isolated perfused liver, lung and kidney preparations.
    Steele JW; Yagen B; Hernandez O; Cox RH; Smith BR; Bend JR
    J Pharmacol Exp Ther; 1981 Oct; 219(1):35-41. PubMed ID: 7288613
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Localization of glutathione conjugation activities toward bromosulfophthalein in perfused rat liver. Studies with the multiple indicator dilution technique.
    Zhao Y; Snel CA; Mulder GJ; Pang KS
    Drug Metab Dispos; 1993; 21(6):1070-8. PubMed ID: 7905386
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Melphalan antitumor efficacy and hepatotoxicity: the effect of variable infusion duration in the hepatic artery.
    Rothbarth J; Woutersen RA; Sparidans RW; van de Velde CJ; Mulder GJ
    J Pharmacol Exp Ther; 2003 Jun; 305(3):1098-103. PubMed ID: 12606622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Verlukast (MK-0679) conjugation with glutathione by rat liver and kidney cytosols and excretion in the bile.
    Nicoll-Griffith DA; Gupta N; Twa SP; Williams H; Trimble LA; Yergey JA
    Drug Metab Dispos; 1995 Oct; 23(10):1085-93. PubMed ID: 8654196
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Formation and biliary excretion of glutathione conjugates of bile acids in the rat as shown by liquid chromatography/electrospray ionization-linear ion trap mass spectrometry.
    Mitamura K; Watanabe S; Mitsumoto Y; Sakai T; Sogabe M; Wakamiya T; Ikegawa S
    Anal Biochem; 2009 Jan; 384(2):224-30. PubMed ID: 18938128
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biosynthesis and biliary excretion of S-conjugates of hexachlorobuta-1,3-diene in the perfused rat liver.
    Gietl YS; Anders MW
    Drug Metab Dispos; 1991; 19(1):274-7. PubMed ID: 1673413
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparison of sulfobromophthalein (BSP) and sulfobromophthalein glutathione (BSP-GSH) disposition under conditions of altered liver function and in the isolated perfused rat liver.
    Yam J; Reeves M; Roberts RJ
    J Lab Clin Med; 1976 Mar; 87(3):373-83. PubMed ID: 1249471
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.