BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 8841395)

  • 1. Substitutions at C2' of daunosamine in the anticancer drug daunorubicin alter its DNA-binding sequence specificity.
    Gao YG; Priebe W; Wang AH
    Eur J Biochem; 1996 Sep; 240(2):331-5. PubMed ID: 8841395
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes.
    Dutta R; Gao YG; Priebe W; Wang AH
    Nucleic Acids Res; 1998 Jun; 26(12):3001-5. PubMed ID: 9611247
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Simultaneous incorporations of two anticancer drugs into DNA. The structures of formaldehyde-cross-linked adducts of daunorubicin-d(CG(araC)GCG) and doxorubicin-d(CA(araC)GTG) complexes at high resolution.
    Zhang H; Gao YG; van der Marel GA; van Boom JH; Wang AH
    J Biol Chem; 1993 May; 268(14):10095-101. PubMed ID: 8486678
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adduct.
    Gao YG; Liaw YC; Li YK; van der Marel GA; van Boom JH; Wang AH
    Proc Natl Acad Sci U S A; 1991 Jun; 88(11):4845-9. PubMed ID: 2052564
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(CGTACG) and d(CGATCG): implications in drug-DNA crosslink.
    Gao YG; Wang AH
    J Biomol Struct Dyn; 1995 Aug; 13(1):103-17. PubMed ID: 8527023
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Formaldehyde cross-links daunorubicin and DNA efficiently: HPLC and X-ray diffraction studies.
    Wang AH; Gao YG; Liaw YC; Li YK
    Biochemistry; 1991 Apr; 30(16):3812-5. PubMed ID: 2018756
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Binding of two novel bisdaunorubicins to DNA studied by NMR spectroscopy.
    Robinson H; Priebe W; Chaires JB; Wang AH
    Biochemistry; 1997 Jul; 36(29):8663-70. PubMed ID: 9289011
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Influence of aglycone modifications on the binding of anthracycline drugs to DNA: the molecular structure of idarubicin and 4-O-demethyl-11-deoxydoxorubicin complexed to d(CGATCG).
    Gao YG; Wang AH
    Anticancer Drug Des; 1991 Jul; 6(3):137-49. PubMed ID: 1872945
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Release of the cyano moiety in the crystal structure of N-cyanomethyl-N-(2-methoxyethyl)-daunomycin complexed with d(CGATCG).
    Saminadin P; Dautant A; Mondon M; Langlois D'estaintot B; Courseille C; Précigoux G
    Eur J Biochem; 2000 Jan; 267(2):457-64. PubMed ID: 10632715
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells.
    Podell ER; Harrington DJ; Taatjes DJ; Koch TH
    Acta Crystallogr D Biol Crystallogr; 1999 Sep; 55(Pt 9):1516-23. PubMed ID: 10489446
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-based design of a new bisintercalating anthracycline antibiotic.
    Chaires JB; Leng F; Przewloka T; Fokt I; Ling YH; Perez-Soler R; Priebe W
    J Med Chem; 1997 Jan; 40(3):261-6. PubMed ID: 9022792
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interactions between an anthracycline antibiotic and DNA: molecular structure of daunomycin complexed to d(CpGpTpApCpG) at 1.2-A resolution.
    Wang AH; Ughetto G; Quigley GJ; Rich A
    Biochemistry; 1987 Feb; 26(4):1152-63. PubMed ID: 3567161
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Solution conformation of the (-)-cis-anti-benzo[a]pyrenyl-dG adduct opposite dC in a DNA duplex: intercalation of the covalently attached BP ring into the helix with base displacement of the modified deoxyguanosine into the major groove.
    Cosman M; Hingerty BE; Luneva N; Amin S; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1996 Jul; 35(30):9850-63. PubMed ID: 8703959
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Degradation of the morpholino ring in the crystal structure of cyanomorpholinodoxorubicin complexed with d(CGATCG).
    Ettorre A; Cirilli M; Ughetto G
    Eur J Biochem; 1998 Dec; 258(2):350-4. PubMed ID: 9874199
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin.
    Taatjes DJ; Gaudiano G; Resing K; Koch TH
    J Med Chem; 1997 Apr; 40(8):1276-86. PubMed ID: 9111302
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate.
    Williams LD; Egli M; Ughetto G; van der Marel GA; van Boom JH; Quigley GJ; Wang AH; Rich A; Frederick CA
    J Mol Biol; 1990 Sep; 215(2):313-20. PubMed ID: 2152325
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure of a DNA-bisdaunomycin complex.
    Hu GG; Shui X; Leng F; Priebe W; Chaires JB; Williams LD
    Biochemistry; 1997 May; 36(20):5940-6. PubMed ID: 9166763
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin.
    Frederick CA; Williams LD; Ughetto G; van der Marel GA; van Boom JH; Rich A; Wang AH
    Biochemistry; 1990 Mar; 29(10):2538-49. PubMed ID: 2334681
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of the topoisomerase II poison 9-amino-[N-(2-dimethylamino)ethyl]acridine-4-carboxamide bound to the DNA hexanucleotide d(CGTACG)2.
    Adams A; Guss JM; Collyer CA; Denny WA; Wakelin LP
    Biochemistry; 1999 Jul; 38(29):9221-33. PubMed ID: 10413496
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sequence selective binding of bis-daunorubicin WP631 to DNA.
    Fox KR; Webster R; Phelps RJ; Fokt I; Priebe W
    Eur J Biochem; 2004 Sep; 271(17):3556-66. PubMed ID: 15317591
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.