BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 8844833)

  • 1. Internalization and translocation of a new chimeric protein composed of Pseudomonas aeruginosa exotoxin A and mouse dihydrofolate reductase as a model system.
    Guidi-Rontani C
    Protein Eng; 1996 Jul; 9(7):611-6. PubMed ID: 8844833
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells.
    Arora N; Klimpel KR; Singh Y; Leppla SH
    J Biol Chem; 1992 Aug; 267(22):15542-8. PubMed ID: 1639793
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Anthrax toxin-mediated delivery of the Pseudomonas exotoxin A enzymatic domain to the cytosol of tumor cells via cleavable ubiquitin fusions.
    Bachran C; Morley T; Abdelazim S; Fattah RJ; Liu S; Leppla SH
    mBio; 2013 Apr; 4(3):e00201-13. PubMed ID: 23631917
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytotoxic activity of a recombinant chimaeric protein between Pseudomonas aeruginosa exotoxin A and Corynebacterium diphtheriae diphtheria toxin.
    Guidi-Rontani C
    Mol Microbiol; 1992 May; 6(10):1281-7. PubMed ID: 1640830
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Barnase toxin: a new chimeric toxin composed of pseudomonas exotoxin A and barnase.
    Prior TI; FitzGerald DJ; Pastan I
    Cell; 1991 Mar; 64(5):1017-23. PubMed ID: 1900455
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Translocation mediated by domain II of Pseudomonas exotoxin A: transport of barnase into the cytosol.
    Prior TI; FitzGerald DJ; Pastan I
    Biochemistry; 1992 Apr; 31(14):3555-9. PubMed ID: 1567815
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dexamethasone negatively regulates the activity of a chimeric dihydrofolate reductase/glucocorticoid receptor protein.
    Israel DI; Kaufman RJ
    Proc Natl Acad Sci U S A; 1993 May; 90(9):4290-4. PubMed ID: 8483945
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Systematic comparison of single-chain Fv antibody-fusion toxin constructs containing Pseudomonas Exotoxin A or saporin produced in different microbial expression systems.
    Della Cristina P; Castagna M; Lombardi A; Barison E; Tagliabue G; Ceriotti A; Koutris I; Di Leandro L; Giansanti F; Vago R; Ippoliti R; Flavell SU; Flavell DJ; Colombatti M; Fabbrini MS
    Microb Cell Fact; 2015 Feb; 14():19. PubMed ID: 25889802
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cellular uptake of Clostridium botulinum C2 toxin: membrane translocation of a fusion toxin requires unfolding of its dihydrofolate reductase domain.
    Haug G; Wilde C; Leemhuis J; Meyer DK; Aktories K; Barth H
    Biochemistry; 2003 Dec; 42(51):15284-91. PubMed ID: 14690438
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Pseudomonas aeruginosa exotoxin A translocation domain facilitates the routing of CPP-protein cargos to the cytosol of eukaryotic cells.
    Mohammed AF; Abdul-Wahid A; Huang EH; Bolewska-Pedyczak E; Cydzik M; Broad AE; Gariépy J
    J Control Release; 2012 Nov; 164(1):58-64. PubMed ID: 23075769
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A dominant-negative approach that prevents diphthamide formation confers resistance to Pseudomonas exotoxin A and diphtheria toxin.
    Roy V; Ghani K; Caruso M
    PLoS One; 2010 Dec; 5(12):e15753. PubMed ID: 21203470
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel fusion toxin derived from an EpCAM-specific designed ankyrin repeat protein has potent antitumor activity.
    Martin-Killias P; Stefan N; Rothschild S; Plückthun A; Zangemeister-Wittke U
    Clin Cancer Res; 2011 Jan; 17(1):100-10. PubMed ID: 21075824
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Basic fibroblast growth factor-Pseudomonas exotoxin chimeric proteins; comparison with acidic fibroblast growth factor-Pseudomonas exotoxin.
    Gawlak SL; Pastan I; Siegall CB
    Bioconjug Chem; 1993; 4(6):483-9. PubMed ID: 7508267
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Redirecting Pseudomonas exotoxin.
    FitzGerald D; Pastan I
    Semin Cell Biol; 1991 Feb; 2(1):31-7. PubMed ID: 1954341
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ability of methotrexate to inhibit translocation to the cytosol of dihydrofolate reductase fused to diphtheria toxin.
    Klingenberg O; Olsnes S
    Biochem J; 1996 Jan; 313 ( Pt 2)(Pt 2):647-53. PubMed ID: 8573105
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Furin activates Pseudomonas exotoxin A by specific cleavage in vivo and in vitro.
    Inocencio NM; Moehring JM; Moehring TJ
    J Biol Chem; 1994 Dec; 269(50):31831-5. PubMed ID: 7989356
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Drosophila dihydrofolate reductase mutations confer antifolate resistance to mammalian cells.
    Affleck JG; Al-Batayneh KM; Neumann K; Cole SP; Walker VK
    Eur J Pharmacol; 2006 Jan; 529(1-3):71-8. PubMed ID: 16325803
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Residues 1-254 of anthrax toxin lethal factor are sufficient to cause cellular uptake of fused polypeptides.
    Arora N; Leppla SH
    J Biol Chem; 1993 Feb; 268(5):3334-41. PubMed ID: 8429009
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The heparin-binding domain of heparin-binding EGF-like growth factor can target Pseudomonas exotoxin to kill cells exclusively through heparan sulfate proteoglycans.
    Mesri EA; Ono M; Kreitman RJ; Klagsbrun M; Pastan I
    J Cell Sci; 1994 Sep; 107 ( Pt 9)():2599-608. PubMed ID: 7844173
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transfection of a nonactive site mutant murine DHFR cDNA (the tryptophan 15 mutant) into Chinese hamster ovary and mouse marrow progenitor cells imparts MTX resistance in vitro.
    Banerjee D; Zhao SC; Tong Y; Steinherz J; Gritsman K; Bertino JR
    Cancer Gene Ther; 1994 Sep; 1(3):181-4. PubMed ID: 7621249
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.