BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

339 related articles for article (PubMed ID: 8860834)

  • 1. Correction of ornithine transcarbamylase deficiency in adult spf(ash) mice and in OTC-deficient human hepatocytes with recombinant adenoviruses bearing the CAG promoter.
    Kiwaki K; Kanegae Y; Saito I; Komaki S; Nakamura K; Miyazaki JI; Endo F; Matsuda I
    Hum Gene Ther; 1996 May; 7(7):821-30. PubMed ID: 8860834
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Efficient mitochondrial import of newly synthesized ornithine transcarbamylase (OTC) and correction of secondary metabolic alterations in spf(ash) mice following gene therapy of OTC deficiency.
    Zimmer KP; Bendiks M; Mori M; Kominami E; Robinson MB; Ye X; Wilson JM
    Mol Med; 1999 Apr; 5(4):244-53. PubMed ID: 10448647
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gene therapy for ornithine transcarbamylase deficiency.
    Kiwaki K; Matsuda I
    Acta Paediatr Jpn; 1996 Apr; 38(2):189-92. PubMed ID: 8677801
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phenotypic correction of ornithine transcarbamylase deficiency using low dose helper-dependent adenoviral vectors.
    Brunetti-Pierri N; Clarke C; Mane V; Palmer DJ; Lanpher B; Sun Q; O'Brien W; Lee B
    J Gene Med; 2008 Aug; 10(8):890-6. PubMed ID: 18563850
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Long-term correction of ammonia metabolism and prolonged survival in ornithine transcarbamylase-deficient mice following liver-directed treatment with adeno-associated viral vectors.
    Moscioni D; Morizono H; McCarter RJ; Stern A; Cabrera-Luque J; Hoang A; Sanmiguel J; Wu D; Bell P; Gao GP; Raper SE; Wilson JM; Batshaw ML
    Mol Ther; 2006 Jul; 14(1):25-33. PubMed ID: 16677864
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector.
    Stratford-Perricaudet LD; Levrero M; Chasse JF; Perricaudet M; Briand P
    Hum Gene Ther; 1990; 1(3):241-56. PubMed ID: 2081192
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prolonged metabolic correction in adult ornithine transcarbamylase-deficient mice with adenoviral vectors.
    Ye X; Robinson MB; Batshaw ML; Furth EE; Smith I; Wilson JM
    J Biol Chem; 1996 Feb; 271(7):3639-46. PubMed ID: 8631974
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Correction of mouse ornithine transcarbamylase deficiency by gene transfer into the germ line.
    Cavard C; Grimber G; Dubois N; Chasse JF; Bennoun M; Minet-Thuriaux M; Kamoun P; Briand P
    Nucleic Acids Res; 1988 Mar; 16(5):2099-110. PubMed ID: 3162766
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Preclinical evaluation of a clinical candidate AAV8 vector for ornithine transcarbamylase (OTC) deficiency reveals functional enzyme from each persisting vector genome.
    Wang L; Morizono H; Lin J; Bell P; Jones D; McMenamin D; Yu H; Batshaw ML; Wilson JM
    Mol Genet Metab; 2012 Feb; 105(2):203-11. PubMed ID: 22133298
    [TBL] [Abstract][Full Text] [Related]  

  • 10. AAV2/8-mediated correction of OTC deficiency is robust in adult but not neonatal Spf(ash) mice.
    Cunningham SC; Spinoulas A; Carpenter KH; Wilcken B; Kuchel PW; Alexander IE
    Mol Ther; 2009 Aug; 17(8):1340-6. PubMed ID: 19384294
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Retroviral-mediated gene transfer of human ornithine transcarbamylase into primary hepatocytes of spf and spf-ash mice.
    Grompe M; Jones SN; Loulseged H; Caskey CT
    Hum Gene Ther; 1992 Feb; 3(1):35-44. PubMed ID: 1562638
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AAV-encoded OTC activity persisting to adulthood following delivery to newborn spf(ash) mice is insufficient to prevent shRNA-induced hyperammonaemia.
    Cunningham SC; Kok CY; Spinoulas A; Carpenter KH; Alexander IE
    Gene Ther; 2013 Dec; 20(12):1184-7. PubMed ID: 24108150
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Importance of ornithine transcarbamylase (OTC) deficiency in small intestine for urinary orotic acid excretion: analysis of OTC-deficient spf-ash mice with OTC transgene.
    Saheki T; Mori K; Kobayashi K; Horiuchi M; Shige T; Obara T; Suzuki S; Mori M; Yamamura K
    Biochim Biophys Acta; 1995 Jan; 1270(1):87-93. PubMed ID: 7827141
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency.
    Raper SE; Yudkoff M; Chirmule N; Gao GP; Nunes F; Haskal ZJ; Furth EE; Propert KJ; Robinson MB; Magosin S; Simoes H; Speicher L; Hughes J; Tazelaar J; Wivel NA; Wilson JM; Batshaw ML
    Hum Gene Ther; 2002 Jan; 13(1):163-75. PubMed ID: 11779420
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes.
    Morsy MA; Alford EL; Bett A; Graham FL; Caskey CT
    J Clin Invest; 1993 Sep; 92(3):1580-6. PubMed ID: 8376608
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differences in the human and mouse amino-terminal leader peptides of ornithine transcarbamylase affect mitochondrial import and efficacy of adenoviral vectors.
    Ye X; Zimmer KP; Brown R; Pabin C; Batshaw ML; Wilson JM; Robinson MB
    Hum Gene Ther; 2001 Jun; 12(9):1035-46. PubMed ID: 11399226
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Long-term correction of ornithine transcarbamylase deficiency by WPRE-mediated overexpression using a helper-dependent adenovirus.
    Mian A; McCormack WM; Mane V; Kleppe S; Ng P; Finegold M; O'Brien WE; Rodgers JR; Beaudet AL; Lee B
    Mol Ther; 2004 Sep; 10(3):492-9. PubMed ID: 15336649
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Developing adenoviral-mediated in vivo gene therapy for ornithine transcarbamylase deficiency.
    Raper SE; Wilson JM; Yudkoff M; Robinson MB; Ye X; Batshaw ML
    J Inherit Metab Dis; 1998; 21 Suppl 1():119-37. PubMed ID: 9686350
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sustained correction of OTC deficiency in spf( ash) mice using optimized self-complementary AAV2/8 vectors.
    Wang L; Wang H; Morizono H; Bell P; Jones D; Lin J; McMenamin D; Yu H; Batshaw ML; Wilson JM
    Gene Ther; 2012 Apr; 19(4):404-10. PubMed ID: 21850052
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Normalization of hair growth in sparse fur-abnormal skin and hair (SPF-ASH) mice by introduction of the rat ornithine transcarbamylase (OTC) gene.
    Shimada T; Tashiro M; Kanzaki T; Noda T; Murakami T; Takiguchi M; Mori M; Yamamura K; Saheki T
    J Dermatol Sci; 1994 Jul; 7 Suppl():S27-32. PubMed ID: 7999674
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.