245 related articles for article (PubMed ID: 8863803)
1. Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives.
Berardi F; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1996 Oct; 39(21):4255-60. PubMed ID: 8863803
[TBL] [Abstract][Full Text] [Related]
2. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
Berardi F; Colabufo NA; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1996 Jan; 39(1):176-82. PubMed ID: 8568804
[TBL] [Abstract][Full Text] [Related]
3. N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands.
Berardi F; Santoro S; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1998 Oct; 41(21):3940-7. PubMed ID: 9767631
[TBL] [Abstract][Full Text] [Related]
4. 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity.
Berardi F; Ferorelli S; Abate C; Colabufo NA; Contino M; Perrone R; Tortorella V
J Med Chem; 2004 Apr; 47(9):2308-17. PubMed ID: 15084129
[TBL] [Abstract][Full Text] [Related]
5. Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma(1) receptor.
Berardi F; Ferorelli S; Abate C; Pedone MP; Colabufo NA; Contino M; Perrone R
J Med Chem; 2005 Dec; 48(26):8237-44. PubMed ID: 16366605
[TBL] [Abstract][Full Text] [Related]
6. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
Leopoldo M; Berardi F; Colabufo NA; Contino M; Lacivita E; Niso M; Perrone R; Tortorella V
J Med Chem; 2004 Dec; 47(26):6616-24. PubMed ID: 15588097
[TBL] [Abstract][Full Text] [Related]
7. 1-aryl-4-[(5-methoxy-1,2,3, 4-tetrahydronaphthalen-1-yl)alkyl]piperazines and their analogues: influence of the stereochemistry of the tetrahydronaphthalen-1-yl nucleus on 5-HT1A receptor affinity and selectivity versus alpha1 and D2 receptors. 5.
Perrone R; Berardi F; Colabufo NA; Leopoldo M; Tortorella V
J Med Chem; 1999 Feb; 42(3):490-6. PubMed ID: 9986719
[TBL] [Abstract][Full Text] [Related]
8. [[(Arylpiperazinyl)alkyl]thio]thieno[2,3-d]pyrimidinone derivatives as high-affinity, selective 5-HT1A receptor ligands.
Modica M; Santagati M; Russo F; Parotti L; De Gioia L; Selvaggini C; Salmona M; Mennini T
J Med Chem; 1997 Feb; 40(4):574-85. PubMed ID: 9046348
[TBL] [Abstract][Full Text] [Related]
9. [3H]RS-23597-190, a potent 5-hydroxytryptamine4 antagonist labels sigma-1 but not sigma-2 binding sites in guinea pig brain.
Bonhaus DW; Loury DN; Jakeman LB; Hsu SA; To ZP; Leung E; Zeitung KD; Eglen RM; Wong EH
J Pharmacol Exp Ther; 1994 Oct; 271(1):484-93. PubMed ID: 7965749
[TBL] [Abstract][Full Text] [Related]
10. Pharmacological and autoradiographic discrimination of sigma and phencyclidine receptor binding sites in brain with (+)-[3H]SKF 10,047, (+)-[3H]-3-[3-hydroxyphenyl]-N-(1-propyl)piperidine and [3H]-1-[1-(2-thienyl)cyclohexyl]piperidine.
Largent BL; Gundlach AL; Snyder SH
J Pharmacol Exp Ther; 1986 Aug; 238(2):739-48. PubMed ID: 3016248
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and quantitative structure-activity relationships of N-(1-benzylpiperidin-4-yl)phenylacetamides and related analogues as potent and selective sigma1 receptor ligands.
Huang Y; Hammond PS; Whirrett BR; Kuhner RJ; Wu L; Childers SR; Mach RH
J Med Chem; 1998 Jun; 41(13):2361-70. PubMed ID: 9632369
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and structure-activity relationships of a new model of arylpiperazines. 4. 1-[omega-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene) - 2, 5-pyrrolidinediones and -3-(9H-fluoren-9-ylidene)-2, 5-pyrrolidinediones: study of the steric requirements of the terminal amide fragment on 5-HT1A affinity/selectivity.
López-Rodríguez ML; Morcillo MJ; Rovat TK; Fernández E; Vicente B; Sanz AM; Hernández M; Orensanz L
J Med Chem; 1999 Jan; 42(1):36-49. PubMed ID: 9888831
[TBL] [Abstract][Full Text] [Related]
13. DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'-oxoethyl)- piperidine HBr], a sigma and 5-hydroxytryptamine2 receptor antagonist: receptor-binding, electrophysiological and neuropharmacological profiles.
Tam SW; Steinfels GF; Gilligan PJ; Schmidt WK; Cook L
J Pharmacol Exp Ther; 1992 Dec; 263(3):1167-74. PubMed ID: 1361572
[TBL] [Abstract][Full Text] [Related]
14. Novel derivatives of 2-pyridinemethylamine as selective, potent, and orally active agonists at 5-HT1A receptors.
Vacher B; Bonnaud B; Funes P; Jubault N; Koek W; Assié MB; Cosi C; Kleven M
J Med Chem; 1999 May; 42(9):1648-60. PubMed ID: 10229633
[TBL] [Abstract][Full Text] [Related]
15. A multireceptorial binding reinvestigation on an extended class of sigma ligands: N-[omega-(indan-1-yl and tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine reveal high affinities towards sigma1 and EBP sites.
Berardi F; Ferorelli S; Colabufo NA; Leopoldo M; Perrone R; Tortorella V
Bioorg Med Chem; 2001 May; 9(5):1325-35. PubMed ID: 11377189
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, configuration, and activity of isomeric 2-phenyl-2-(N-piperidinyl)bicyclo[3.1.0]hexanes at phencyclidine and sigma binding sites.
de Costa BR; Mattson MV; George C; Linders JT
J Med Chem; 1992 Dec; 35(25):4704-12. PubMed ID: 1469699
[TBL] [Abstract][Full Text] [Related]
17. Novel (4-phenylpiperidinyl)- and (4-phenylpiperazinyl)alkyl-spaced esters of 1-phenylcyclopentanecarboxylic acids as potent sigma-selective compounds.
Hudkins RL; Mailman RB; DeHaven-Hudkins DL
J Med Chem; 1994 Jun; 37(13):1964-70. PubMed ID: 8027978
[TBL] [Abstract][Full Text] [Related]
18. Rigid phencyclidine analogues. Binding to the phencyclidine and sigma 1 receptors.
Moriarty RM; Enache LA; Zhao L; Gilardi R; Mattson MV; Prakash O
J Med Chem; 1998 Feb; 41(4):468-77. PubMed ID: 9484497
[TBL] [Abstract][Full Text] [Related]
19. Investigation of σ receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines.
Niso M; Abate C; Ferorelli S; Cassano G; Gasparre G; Perrone R; Berardi F
Bioorg Med Chem; 2013 Apr; 21(7):1865-9. PubMed ID: 23415062
[TBL] [Abstract][Full Text] [Related]
20. Synthesis of chiral 1-[omega-(4-chlorophenoxy)alkyl]-4-methylpiperidines and their biological evaluation at sigma1, sigma2, and sterol delta8-delta7 isomerase sites.
Berardi F; Loiodice F; Fracchiolla G; Colabufo NA; Perrone R; Tortorella V
J Med Chem; 2003 May; 46(11):2117-24. PubMed ID: 12747784
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]