112 related articles for article (PubMed ID: 8869645)
21. Enhancement of diphtheria toxin potency by replacement of the receptor binding domain with tetanus toxin C-fragment: a potential vector for delivering heterologous proteins to neurons.
Francis JW; Brown RH; Figueiredo D; Remington MP; Castillo O; Schwarzschild MA; Fishman PS; Murphy JR; vanderSpek JC
J Neurochem; 2000 Jun; 74(6):2528-36. PubMed ID: 10820215
[TBL] [Abstract][Full Text] [Related]
22. Diphtheria-related peptide hormone gene fusions: a molecular genetic approach to chimeric toxin development.
Murphy JR
Cancer Treat Res; 1988; 37():123-40. PubMed ID: 2908622
[TBL] [Abstract][Full Text] [Related]
23. The effects of helix breaking mutations in the diphtheria toxin transmembrane domain helix layers of the fusion toxin DAB389IL-2.
Hu HY; Huynh PD; Murphy JR; vanderSpek JC
Protein Eng; 1998 Sep; 11(9):811-7. PubMed ID: 9796831
[TBL] [Abstract][Full Text] [Related]
24. Synthesis and cytotoxic profile of a diphtheria toxin-neurotrophin-4 chimera.
Negro A; Skaper SD
J Neurochem; 1997 Feb; 68(2):554-63. PubMed ID: 9003040
[TBL] [Abstract][Full Text] [Related]
25. [Design and expression of a diphtheria toxin hybrid protein and human interleukin-2 gene in Escherichia coli].
Shemiakin IG; Anisimova VA; Mitrofanova GN
Mol Biol (Mosk); 1992; 26(5):1088-98. PubMed ID: 1470175
[TBL] [Abstract][Full Text] [Related]
26. Cellular processing of the interleukin-2 fusion toxin DAB486-IL-2 and efficient delivery of diphtheria fragment A to the cytosol of target cells requires Arg194.
Williams DP; Wen Z; Watson RS; Boyd J; Strom TB; Murphy JR
J Biol Chem; 1990 Nov; 265(33):20673-7. PubMed ID: 2243114
[TBL] [Abstract][Full Text] [Related]
27. Diphtheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein.
Williams DP; Parker K; Bacha P; Bishai W; Borowski M; Genbauffe F; Strom TB; Murphy JR
Protein Eng; 1987 Dec; 1(6):493-8. PubMed ID: 3334101
[TBL] [Abstract][Full Text] [Related]
28. Maintenance of the hydrophobic face of the diphtheria toxin amphipathic transmembrane helix 1 is essential for the efficient delivery of the catalytic domain to the cytosol of target cells.
vanderSpek JC; Howland K; Friedman T; Murphy JR
Protein Eng; 1994 Aug; 7(8):985-9. PubMed ID: 7809038
[TBL] [Abstract][Full Text] [Related]
29. Expression and purification of the recombinant diphtheria fusion toxin DT388IL3 for phase I clinical trials.
Urieto JO; Liu T; Black JH; Cohen KA; Hall PD; Willingham MC; Pennell LK; Hogge DE; Kreitman RJ; Frankel AE
Protein Expr Purif; 2004 Jan; 33(1):123-33. PubMed ID: 14680969
[TBL] [Abstract][Full Text] [Related]
30. Characterization of diphtheria fusion proteins targeted to the human interleukin-3 receptor.
Frankel AE; Ramage J; Kiser M; Alexander R; Kucera G; Miller MS
Protein Eng; 2000 Aug; 13(8):575-81. PubMed ID: 10964987
[TBL] [Abstract][Full Text] [Related]
31. Genetic construction and properties of a diphtheria toxin-related substance P fusion protein: in vitro destruction of cells bearing substance P receptors.
Fisher CE; Sutherland JA; Krause JE; Murphy JR; Leeman SE; vanderSpek JC
Proc Natl Acad Sci U S A; 1996 Jul; 93(14):7341-5. PubMed ID: 8692995
[TBL] [Abstract][Full Text] [Related]
32. An intact transmembrane helix 9 is essential for the efficient delivery of the diphtheria toxin catalytic domain to the cytosol of target cells.
vanderSpek J; Cassidy D; Genbauffe F; Huynh PD; Murphy JR
J Biol Chem; 1994 Aug; 269(34):21455-9. PubMed ID: 8063778
[TBL] [Abstract][Full Text] [Related]
33. Targeting diphtheria toxin to growth factor receptors.
Murphy JR; vanderSpek JC
Semin Cancer Biol; 1995 Oct; 6(5):259-67. PubMed ID: 8562903
[TBL] [Abstract][Full Text] [Related]
34. Interaction of an alpha-melanocyte-stimulating hormone-diphtheria toxin fusion protein with melanotropin receptors in human melanoma metastases.
Tatro JB; Wen Z; Entwistle ML; Atkins MB; Smith TJ; Reichlin S; Murphy JR
Cancer Res; 1992 May; 52(9):2545-8. PubMed ID: 1314697
[TBL] [Abstract][Full Text] [Related]
35. Diphtheria toxin-based receptor-specific chimaeric toxins as targeted therapies.
Sweeney EB; Murphy JR
Essays Biochem; 1995; 30():119-31. PubMed ID: 8822152
[TBL] [Abstract][Full Text] [Related]
36. [Construction and expression of the fusion protein DT389-hIL-13 and its cytotoxicity to glioma cell lines].
Tuo HZ; Wang JW; Wang DX; Li JM; Ouyang J; Hong T
Zhonghua Yi Xue Za Zhi; 2004 Jun; 84(12):1024-8. PubMed ID: 15312540
[TBL] [Abstract][Full Text] [Related]
37. Diphtheria toxin-related cytokine fusion proteins: elongation factor 2 as a target for the treatment of neoplastic disease.
vanderSpek J; Cosenza L; Woodworth T; Nichols JC; Murphy JR
Mol Cell Biochem; 1994 Sep; 138(1-2):151-6. PubMed ID: 7898459
[TBL] [Abstract][Full Text] [Related]
38. Diphtheria toxin-based recombinant murine IL-2 fusion toxin for depleting murine regulatory T cells in vivo.
Wei M; Marino J; Trowell A; Zhang H; Stromp Peraino J; Rajasekera PV; Madsen JC; Sachs DH; Huang CA; Benichou G; Wang Z
Protein Eng Des Sel; 2014 Sep; 27(9):289-95. PubMed ID: 25147093
[TBL] [Abstract][Full Text] [Related]
39. IL-4R expression in AIDS-KS cells and response to rhIL-4 and IL-4 toxin (DAB389-IL-4).
Cai J; Zheng T; Murphy J; Waters CA; Lin GY; Gill PS
Invest New Drugs; 1997; 15(4):279-87. PubMed ID: 9547670
[TBL] [Abstract][Full Text] [Related]
40. DAB(389)IL-2 (denileukin diftitox, ONTAK): a new fusion protein technology.
Foss FM
Clin Lymphoma; 2000 Nov; 1 Suppl 1():S27-31. PubMed ID: 11707860
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
