131 related articles for article (PubMed ID: 8869746)
1. rTS gene expression is associated with altered cell sensitivity to thymidylate synthase inhibitors.
Dolnick BJ; Black AR; Winkler PM; Schindler K; Hsueh CT
Adv Enzyme Regul; 1996; 36():165-80. PubMed ID: 8869746
[TBL] [Abstract][Full Text] [Related]
2. Recent advances in the study of rTS proteins. rTS expression during growth and in response to thymidylate synthase inhibitors in human tumor cells.
Dolnick BJ; Lu K; Yin MB; Rustum YM
Adv Enzyme Regul; 1997; 37():95-109. PubMed ID: 9381988
[TBL] [Abstract][Full Text] [Related]
3. The means to an end of tumor cell resistance to chemotherapeutic drugs targeting thymidylate synthase: shoot the messenger.
Berg RW; Ferguso PJ; DeMoor JM; Vincen MD; Koropatnick J
Curr Drug Targets; 2002 Aug; 3(4):297-309. PubMed ID: 12102601
[TBL] [Abstract][Full Text] [Related]
4. The rTS signaling pathway as a target for drug development.
Dolnick BJ
Clin Colorectal Cancer; 2005 May; 5(1):57-60. PubMed ID: 15929807
[TBL] [Abstract][Full Text] [Related]
5. Isolation and expression of rat thymidylate synthase cDNA: phylogenetic comparison with human and mouse thymidylate synthases.
Cieśla J; Weiner KX; Weiner RS; Reston JT; Maley GF; Maley F
Biochim Biophys Acta; 1995 Apr; 1261(2):233-42. PubMed ID: 7711067
[TBL] [Abstract][Full Text] [Related]
6. Pharmacogenomic dissection of resistance to thymidylate synthase inhibitors.
Wang W; Marsh S; Cassidy J; McLeod HL
Cancer Res; 2001 Jul; 61(14):5505-10. PubMed ID: 11454699
[TBL] [Abstract][Full Text] [Related]
7. Alternate splicing of the rTS gene product and its overexpression in a 5-fluorouracil-resistant cell line.
Dolnick BJ; Black AR
Cancer Res; 1996 Jul; 56(14):3207-10. PubMed ID: 8764108
[TBL] [Abstract][Full Text] [Related]
8. Natural antisense (rTSalpha) RNA induces site-specific cleavage of thymidylate synthase mRNA.
Chu J; Dolnick BJ
Biochim Biophys Acta; 2002 Jul; 1587(2-3):183-93. PubMed ID: 12084460
[TBL] [Abstract][Full Text] [Related]
9. Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.
Banerjee D; Mayer-Kuckuk P; Capiaux G; Budak-Alpdogan T; Gorlick R; Bertino JR
Biochim Biophys Acta; 2002 Jul; 1587(2-3):164-73. PubMed ID: 12084458
[TBL] [Abstract][Full Text] [Related]
10. Determinants of trifluorothymidine sensitivity and metabolism in colon and lung cancer cells.
Temmink OH; de Bruin M; Comijn EM; Fukushima M; Peters GJ
Anticancer Drugs; 2005 Mar; 16(3):285-92. PubMed ID: 15711180
[TBL] [Abstract][Full Text] [Related]
11. A novel function for the rTS gene.
Dolnick BJ; Angelino NJ; Dolnick R; Sufrin JR
Cancer Biol Ther; 2003; 2(4):364-9. PubMed ID: 14508106
[TBL] [Abstract][Full Text] [Related]
12. Mechanisms of acquired resistance to thymidylate synthase inhibitors: the role of enzyme stability.
Kitchens ME; Forsthoefel AM; Barbour KW; Spencer HT; Berger FG
Mol Pharmacol; 1999 Nov; 56(5):1063-70. PubMed ID: 10531414
[TBL] [Abstract][Full Text] [Related]
13. Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels.
Giovannetti E; Backus HH; Wouters D; Ferreira CG; van Houten VM; Brakenhoff RH; Poupon MF; Azzarello A; Pinedo HM; Peters GJ
Br J Cancer; 2007 Mar; 96(5):769-75. PubMed ID: 17339891
[TBL] [Abstract][Full Text] [Related]
14. The role of thymidylate synthase in cellular regulation.
Chu E; Allegra CJ
Adv Enzyme Regul; 1996; 36():143-63. PubMed ID: 8869745
[TBL] [Abstract][Full Text] [Related]
15. Cloning and characterization of a naturally occurring antisense RNA to human thymidylate synthase mRNA.
Dolnick BJ
Nucleic Acids Res; 1993 Apr; 21(8):1747-52. PubMed ID: 8493092
[TBL] [Abstract][Full Text] [Related]
16. Mechanisms of action of FdUMP[10]: metabolite activation and thymidylate synthase inhibition.
Bijnsdorp IV; Comijn EM; Padron JM; Gmeiner WH; Peters GJ
Oncol Rep; 2007 Jul; 18(1):287-91. PubMed ID: 17549381
[TBL] [Abstract][Full Text] [Related]
17. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
[TBL] [Abstract][Full Text] [Related]
18. Trifluorothymidine resistance is associated with decreased thymidine kinase and equilibrative nucleoside transporter expression or increased secretory phospholipase A2.
Temmink OH; Bijnsdorp IV; Prins HJ; Losekoot N; Adema AD; Smid K; Honeywell RJ; Ylstra B; Eijk PP; Fukushima M; Peters GJ
Mol Cancer Ther; 2010 Apr; 9(4):1047-57. PubMed ID: 20371715
[TBL] [Abstract][Full Text] [Related]
19. Antisense targeting of thymidylate synthase (TS) mRNA increases TS gene transcription and TS protein: effects on human tumor cell sensitivity to TS enzyme-inhibiting drugs.
Jason TL; Berg RW; Vincent MD; Koropatnick J
Gene Expr; 2007; 13(4-5):227-39. PubMed ID: 17605297
[TBL] [Abstract][Full Text] [Related]
20. Effect of hammerhead ribozyme against human thymidylate synthase on the cytotoxicity of thymidylate synthase inhibitors.
Kobayashi H; Takemura Y; Miyachi H; Skelton L; Jackman AL
Jpn J Cancer Res; 1995 Nov; 86(11):1014-8. PubMed ID: 8567390
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]