BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

95 related articles for article (PubMed ID: 8874137)

  • 21. (-)U50,488H [(trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide] induces internalization and down-regulation of the human, but not the rat, kappa-opioid receptor: structural basis for the differential regulation.
    Zhang F; Li J; Li JG; Liu-Chen LY
    J Pharmacol Exp Ther; 2002 Sep; 302(3):1184-92. PubMed ID: 12183679
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mu antagonist properties of kappa agonists in a model of rat urinary bladder motility in vivo.
    Sheldon RJ; Nunan L; Porreca F
    J Pharmacol Exp Ther; 1987 Oct; 243(1):234-40. PubMed ID: 2822899
    [TBL] [Abstract][Full Text] [Related]  

  • 23. kappa -opioid receptor stimulation induces arrhythmia in the isolated rat heart via the protein kinase C/Na(+)-H(+)exchange pathway.
    Bian JS; Pei JM; Cheung CS; Zhang WM; Wong TM
    J Mol Cell Cardiol; 2000 Aug; 32(8):1415-27. PubMed ID: 10900168
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Differential regulation of the human kappa opioid receptor by agonists: etorphine and levorphanol reduced dynorphin A- and U50,488H-induced internalization and phosphorylation.
    Li JG; Zhang F; Jin XL; Liu-Chen LY
    J Pharmacol Exp Ther; 2003 May; 305(2):531-40. PubMed ID: 12606694
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Kappa-opioid receptor agonist U50,488H modulates cocaine and morphine self-administration in drug-naive rats and mice.
    Kuzmin AV; Semenova S; Gerrits MA; Zvartau EE; Van Ree JM
    Eur J Pharmacol; 1997 Mar; 321(3):265-71. PubMed ID: 9085036
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The kappa-opioid receptor agonist U50,488H induces acute physical dependence in guinea-pigs.
    Brent PJ; Chahl LA; Cantarell PA; Kavanagh C
    Eur J Pharmacol; 1993 Sep; 241(2-3):149-56. PubMed ID: 7902288
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Effects of U50,488H on hypoxia pulmonary hypertension and its underlying mechanism.
    Li J; Zhang P; Zhang QY; Zhang SM; Guo HT; Bi H; Wang YM; Sun X; Liu JC; Cheng L; Cui Q; Yu SQ; Kaye AD; Yi DH; Pei JM
    Vascul Pharmacol; 2009; 51(2-3):72-7. PubMed ID: 19351568
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Activation of κ-opioid receptor by U50,488H improves vascular dysfunction in streptozotocin-induced diabetic rats.
    Zhou X; Wang D; Zhang Y; Zhang J; Xiang D; Wang H
    BMC Endocr Disord; 2015 Feb; 15():7. PubMed ID: 25887435
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inhibition of interleukin-1 and tumor necrosis factor-alpha synthesis following treatment of macrophages with the kappa opioid agonist U50, 488H.
    Belkowski SM; Alicea C; Eisenstein TK; Adler MW; Rogers TJ
    J Pharmacol Exp Ther; 1995 Jun; 273(3):1491-6. PubMed ID: 7791124
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Intrathecal administration of dynorphin A and its fragments increase heart rate and arterial pressure in the urethane anesthetized rat: mediation by a nonopioid mechanism.
    Rochford J; Godin C; Henry JL
    Brain Res; 1991 Nov; 565(1):67-77. PubMed ID: 1685349
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Effects of ACEA-1328, a NMDA receptor/glycine site antagonist, on U50,488H-induced antinociception and tolerance.
    Lutfy K; Doan P; Nguyen M; Weber E
    Eur J Pharmacol; 1999 Nov; 384(1):1-5. PubMed ID: 10611412
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Role of protein kinase C-epsilon in the development of kappa-opioid receptor tolerance to U50,488H in rat ventricular myocytes.
    Zhou JJ; Bian JS; Pei JM; Wu S; Li HY; Wong TM
    Br J Pharmacol; 2002 Apr; 135(7):1675-84. PubMed ID: 11934807
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Determination of sites of U50,488H-promoted phosphorylation of the mouse κ opioid receptor (KOPR): disconnect between KOPR phosphorylation and internalization.
    Chen C; Chiu YT; Wu W; Huang P; Mann A; Schulz S; Liu-Chen LY
    Biochem J; 2016 Feb; 473(4):497-508. PubMed ID: 26635353
    [TBL] [Abstract][Full Text] [Related]  

  • 34. κ-opioid receptor activation prevents against arrhythmias by preserving Cx43 protein via alleviation of intracellular calcium.
    Shi QX; Zhang LJ; Yao Y; Zhang QY; Wang W; Li J; Shang YL; Bi H; Zhang SM; Guo HT; Wang YM; Yu SQ; Yi DH; Bueno FR; Kaye AD; Pei JM
    Am J Ther; 2013; 20(5):493-501. PubMed ID: 23011166
    [TBL] [Abstract][Full Text] [Related]  

  • 35. [The study of effects and mechanism of U50, 488H on electrical coupling during ischemia in the perfused isolated rat heart].
    Mao HJ; Chen BP; Wang HP; Gao YF; Xia Q
    Zhongguo Ying Yong Sheng Li Xue Za Zhi; 2010 Aug; 26(3):261-5. PubMed ID: 21038665
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Dexamethasone modulates hypotension induced by opioids in anaesthetised rats.
    Sorrentino R; Capasso A; d'Emmanuele di Villa Bianca R; Pinto A
    Eur J Pharmacol; 2001 Oct; 430(1):79-85. PubMed ID: 11698066
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Cross-talk between cardiac kappa-opioid and beta-adrenergic receptors in developing hypertensive rats.
    Yu XC; Wang HX; Zhang WM; Wong TM
    J Mol Cell Cardiol; 1999 Mar; 31(3):597-605. PubMed ID: 10198190
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Vasculoprotective effect of U50,488H in rats exposed to chronic hypoxia: role of Akt-stimulated NO production.
    Li J; Shi QX; Fan R; Zhang LJ; Zhang SM; Guo HT; Wang YM; Kaye AJ; Kaye AD; Bueno FR; Xu XZ; Yu SQ; Yi DH; Pei JM
    J Appl Physiol (1985); 2013 Jan; 114(2):238-44. PubMed ID: 23139366
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Kappa-opioid receptor stimulation inhibits growth of neonatal rat ventricular myocytes.
    Wang G; Wang H; Yang Y; Wong TM
    Eur J Pharmacol; 2004 Sep; 498(1-3):53-8. PubMed ID: 15363975
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Chronic U50,488H abolishes inositol 1,4,5-trisphosphate and intracellular Ca2+ elevations evoked by kappa-opioid receptor in rat myocytes.
    Sheng JZ; Wong TM
    Eur J Pharmacol; 1996 Jul; 307(3):323-9. PubMed ID: 8836621
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.