BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

889 related articles for article (PubMed ID: 8886607)

  • 21. An inhibitory monoclonal antibody to human cytochrome P450 2A6 defines its role in the metabolism of coumarin, 7-ethoxycoumarin and 4-nitroanisole in human liver.
    Sai Y; Yang TJ; Krausz KW; Gonzalez FJ; Gelboin HV
    Pharmacogenetics; 1999 Apr; 9(2):229-37. PubMed ID: 10376770
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor.
    Chiba M; Hensleigh M; Nishime JA; Balani SK; Lin JH
    Drug Metab Dispos; 1996 Mar; 24(3):307-14. PubMed ID: 8820421
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Human cytochrome P450 isozymes in metabolism and health effects of gasoline ethers.
    Hong JY; Wang YY; Mohr SN; Bondoc FY; Deng C
    Res Rep Health Eff Inst; 2001 May; (102):7-27; discussion 95-109. PubMed ID: 11504148
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Modulation of the reductive metabolism of halothane by microsomal cytochrome b5 in rat liver.
    Tamura S; Kawata S; Sugiyama T; Tarui S
    Biochim Biophys Acta; 1987 Dec; 926(3):231-8. PubMed ID: 3689822
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Identification of the human liver microsomal cytochrome P450s involved in the metabolism of N-nitrosodi-n-propylamine.
    Teiber JF; Hollenberg PF
    Carcinogenesis; 2000 Aug; 21(8):1559-66. PubMed ID: 10910959
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM; Murray M
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Reductive halothane metabolite formation and halothane binding in rat hepatic microsomes.
    Baker MT; Van Dyke RA
    Chem Biol Interact; 1984 Apr; 49(1-2):121-32. PubMed ID: 6722932
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The mechanism of reductive dehalogenation of halothane by liver cytochrome P450.
    Ahr HJ; King LJ; Nastainczyk W; Ullrich V
    Biochem Pharmacol; 1982 Feb; 31(3):383-90. PubMed ID: 7073765
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Metabolic activation of the halothane metabolite, [14C]2-chloro-1,1-difluoroethene, in hepatic microsomes.
    Baker MT; Bates JN
    Drug Metab Dispos; 1988; 16(2):169-72. PubMed ID: 2898328
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Ropivacaine, a new amide-type local anesthetic agent, is metabolized by cytochromes P450 1A and 3A in human liver microsomes.
    Ekström G; Gunnarsson UB
    Drug Metab Dispos; 1996 Sep; 24(9):955-61. PubMed ID: 8886604
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Halofantrine metabolism in microsomes in man: major role of CYP 3A4 and CYP 3A5.
    Baune B; Flinois JP; Furlan V; Gimenez F; Taburet AM; Becquemont L; Farinotti R
    J Pharm Pharmacol; 1999 Apr; 51(4):419-26. PubMed ID: 10385214
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Identification of cytochrome P4503A4 as the major enzyme responsible for the metabolism of ivermectin by human liver microsomes.
    Zeng Z; Andrew NW; Arison BH; Luffer-Atlas D; Wang RW
    Xenobiotica; 1998 Mar; 28(3):313-21. PubMed ID: 9574819
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Evaluation of the selectivity of In vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities.
    Hickman D; Wang JP; Wang Y; Unadkat JD
    Drug Metab Dispos; 1998 Mar; 26(3):207-15. PubMed ID: 9492382
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450.
    Zhao XJ; Yokoyama H; Chiba K; Wanwimolruk S; Ishizaki T
    J Pharmacol Exp Ther; 1996 Dec; 279(3):1327-34. PubMed ID: 8968357
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Competitive interactions between cytochromes P450 2A6 and 2E1 for NADPH-cytochrome P450 oxidoreductase in the microsomal membranes produced by a baculovirus expression system.
    Tan Y; Patten CJ; Smith T; Yang CS
    Arch Biochem Biophys; 1997 Jun; 342(1):82-91. PubMed ID: 9185616
    [TBL] [Abstract][Full Text] [Related]  

  • 36. In vitro metabolism and drug interaction potential of a new highly potent anti-cytomegalovirus molecule, CMV423 (2-chloro 3-pyridine 3-yl 5,6,7,8-tetrahydroindolizine I-carboxamide).
    Bournique B; Lambert N; Boukaiba R; Martinet M
    Br J Clin Pharmacol; 2001 Jul; 52(1):53-63. PubMed ID: 11453890
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.
    Yoshimoto K; Echizen H; Chiba K; Tani M; Ishizaki T
    Br J Clin Pharmacol; 1995 Apr; 39(4):421-31. PubMed ID: 7640150
    [TBL] [Abstract][Full Text] [Related]  

  • 38. High-throughput cytochrome P450 (CYP) inhibition screening via a cassette probe-dosing strategy. VI. Simultaneous evaluation of inhibition potential of drugs on human hepatic isozymes CYP2A6, 3A4, 2C9, 2D6 and 2E1.
    Bu HZ; Magis L; Knuth K; Teitelbaum P
    Rapid Commun Mass Spectrom; 2001; 15(10):741-8. PubMed ID: 11344532
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Evidence for the stability and cytochrome P450 specificity of the phenobarbital-induced reductive halothane-cytochrome P450 complex formed in rat hepatic microsomes.
    Baker MT; Vasquez MT; Chiang CK
    Biochem Pharmacol; 1991 Jun; 41(11):1691-9. PubMed ID: 2043158
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Identification of CYP3A4 as the predominant isoform responsible for the metabolism of ambroxol in human liver microsomes.
    Ishiguro N; Senda C; Kishimoto W; Sakai K; Funae Y; Igarashi T
    Xenobiotica; 2000 Jan; 30(1):71-80. PubMed ID: 10659952
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 45.