BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

280 related articles for article (PubMed ID: 8887457)

  • 1. Validation of precision-cut liver slices in dynamic organ culture as an in vitro model for studying CYP1A1 and CYP1A2 induction.
    Drahushuk AT; McGarrigle BP; Tai HL; Kitareewan S; Goldstein JA; Olson JR
    Toxicol Appl Pharmacol; 1996 Oct; 140(2):393-403. PubMed ID: 8887457
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Time- and concentration-dependent induction of CYP1A1 and CYP1A2 in precision-cut rat liver slices incubated in dynamic organ culture in the presence of 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Drahushuk AT; McGarrigle BP; Slezak BP; Stegeman JJ; Olson JR
    Toxicol Appl Pharmacol; 1999 Mar; 155(2):127-38. PubMed ID: 10053167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of the dose-response of CYP1B1, CYP1A1, and CYP1A2 in the liver of female Sprague-Dawley rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Walker NJ; Portier CJ; Lax SF; Crofts FG; Li Y; Lucier GW; Sutter TR
    Toxicol Appl Pharmacol; 1999 Feb; 154(3):279-86. PubMed ID: 9931287
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tissue specific induction of cytochrome P450 (CYP) 1A1 and 1B1 in rat liver and lung following in vitro (tissue slice) and in vivo exposure to benzo(a)pyrene.
    Harrigan JA; McGarrigle BP; Sutter TR; Olson JR
    Toxicol In Vitro; 2006 Jun; 20(4):426-38. PubMed ID: 16198082
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regional hepatic CYP1A1 and CYP1A2 induction with 2,3,7,8-tetrachlorodibenzo-p-dioxin evaluated with a multicompartment geometric model of hepatic zonation.
    Andersen ME; Birnbaum LS; Barton HA; Eklund CR
    Toxicol Appl Pharmacol; 1997 May; 144(1):145-55. PubMed ID: 9169078
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dose-response relationships for chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver.
    Tritscher AM; Goldstein JA; Portier CJ; McCoy Z; Clark GC; Lucier GW
    Cancer Res; 1992 Jun; 52(12):3436-42. PubMed ID: 1596902
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential time-course and dose-response relationships of TCDD-induced CYP1B1, CYP1A1, and CYP1A2 proteins in rats.
    Santostefano MJ; Ross DG; Savas U; Jefcoate CR; Birnbaum LS
    Biochem Biophys Res Commun; 1997 Apr; 233(1):20-4. PubMed ID: 9144388
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2,3,7,8 Tetrachlorodibenzo-p-dioxin induction of cytochrome P4501A in cultured rat and human hepatocytes.
    Xu L; Li AP; Kaminski DL; Ruh MF
    Chem Biol Interact; 2000 Feb; 124(3):173-89. PubMed ID: 10728777
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dose-response relationships of tissue distribution and induction of CYP1A1 and CYP1A2 enzymatic activities following acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice.
    Diliberto JJ; Akubue PI; Luebke RW; Birnbaum LS
    Toxicol Appl Pharmacol; 1995 Feb; 130(2):197-208. PubMed ID: 7871533
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytochrome P450 1A1 induction in rat lymphoid tissues following in vivo and in vitro exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin requires protein kinase C.
    Stephen FD; Drahushuk AT; Olson JR
    Toxicology; 1997 Dec; 124(1):39-51. PubMed ID: 9392454
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of subchronic 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on immune system and target gene responses in mice: calculation of benchmark doses for CYP1A1 and CYP1A2 related enzyme activities.
    Vogel C; Donat S; Döhr O; Kremer J; Esser C; Roller M; Abel J
    Arch Toxicol; 1997; 71(6):372-82. PubMed ID: 9195019
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene.
    Harrigan JA; Vezina CM; McGarrigle BP; Ersing N; Box HC; Maccubbin AE; Olson JR
    Toxicol Sci; 2004 Feb; 77(2):307-14. PubMed ID: 14691214
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Relationship between CYP1A enzyme activities and protein levels in rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    DeVito MJ; Beebe LE; Menache M; Birnbaum LS
    J Toxicol Environ Health; 1996 Mar; 47(4):379-94. PubMed ID: 8600290
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dioxin-responsive genes: examination of dose-response relationships using quantitative reverse transcriptase-polymerase chain reaction.
    Vanden Heuvel JP; Clark GC; Kohn MC; Tritscher AM; Greenlee WF; Lucier GW; Bell DA
    Cancer Res; 1994 Jan; 54(1):62-8. PubMed ID: 8261464
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Repeated dose toxicity and relative potency of 1,2,3,4,6,7-hexachloronaphthalene (PCN 66) 1,2,3,5,6,7-hexachloronaphthalene (PCN 67) compared to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for induction of CYP1A1, CYP1A2 and thymic atrophy in female Harlan Sprague-Dawley rats.
    Hooth MJ; Nyska A; Fomby LM; Vasconcelos DY; Vallant M; DeVito MJ; Walker NJ
    Toxicology; 2012 Nov; 301(1-3):85-93. PubMed ID: 22813907
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcriptional activation of avian CYP1A4 and CYP1A5 by 2,3,7, 8-tetrachlorodibenzo-p-dioxin: differences in gene expression and regulation compared to mammalian CYP1A1 and CYP1A2.
    Mahajan SS; Rifkind AB
    Toxicol Appl Pharmacol; 1999 Feb; 155(1):96-106. PubMed ID: 10036222
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A pharmacodynamic analysis of TCDD-induced cytochrome P450 gene expression in multiple tissues: dose- and time-dependent effects.
    Santostefano MJ; Wang X; Richardson VM; Ross DG; DeVito MJ; Birnbaum LS
    Toxicol Appl Pharmacol; 1998 Aug; 151(2):294-310. PubMed ID: 9707506
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Detection of CYP1A1 protein in human liver and induction by TCDD in precision-cut liver slices incubated in dynamic organ culture.
    Drahushuk AT; McGarrigle BP; Larsen KE; Stegeman JJ; Olson JR
    Carcinogenesis; 1998 Aug; 19(8):1361-8. PubMed ID: 9744530
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of chlorinated hydrocarbons on expression of cytochrome P450 1A1, 1A2 and 1B1 and 2- and 4-hydroxylation of 17beta-estradiol in female Sprague-Dawley rats.
    Badawi AF; Cavalieri EL; Rogan EG
    Carcinogenesis; 2000 Aug; 21(8):1593-9. PubMed ID: 10910964
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Toxicology and carcinogenesis studies of a binary mixture of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (Cas No. 57465-28-8) and 2,3',4,4',5-pentachlorobiphenyl (PCB 118) (Cas No. 31508-00-6) in female Harlan Sprague-Dawley rats (gavage studies).
    National Toxicology Program
    Natl Toxicol Program Tech Rep Ser; 2006 Nov; (531):1-218. PubMed ID: 17342196
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.