These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 8889848)

  • 1. Bisphosphonates induce apoptosis in mouse macrophage-like cells in vitro by a nitric oxide-independent mechanism.
    Rogers MJ; Chilton KM; Coxon FP; Lawry J; Smith MO; Suri S; Russell RG
    J Bone Miner Res; 1996 Oct; 11(10):1482-91. PubMed ID: 8889848
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heterocycle-containing bisphosphonates cause apoptosis and inhibit bone resorption by preventing protein prenylation: evidence from structure-activity relationships in J774 macrophages.
    Luckman SP; Coxon FP; Ebetino FH; Russell RG; Rogers MJ
    J Bone Miner Res; 1998 Nov; 13(11):1668-78. PubMed ID: 9797474
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antagonistic effects of different classes of bisphosphonates in osteoclasts and macrophages in vitro.
    Frith JC; Rogers MJ
    J Bone Miner Res; 2003 Feb; 18(2):204-12. PubMed ID: 12568397
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.
    Luckman SP; Hughes DE; Coxon FP; Graham R; Russell G; Rogers MJ
    J Bone Miner Res; 1998 Apr; 13(4):581-9. PubMed ID: 9556058
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparative effects of five bisphosphonates on apoptosis of macrophage cells in vitro.
    Moreau MF; Guillet C; Massin P; Chevalier S; Gascan H; Baslé MF; Chappard D
    Biochem Pharmacol; 2007 Mar; 73(5):718-23. PubMed ID: 17157266
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bisphosphonates: the first 40 years.
    Russell RG
    Bone; 2011 Jul; 49(1):2-19. PubMed ID: 21555003
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characteristics of clodronate-induced apoptosis in osteoclasts and macrophages.
    Selander KS; Mönkkönen J; Karhukorpi EK; Härkönen P; Hannuniemi R; Väänänen HK
    Mol Pharmacol; 1996 Nov; 50(5):1127-38. PubMed ID: 8913344
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein synthesis is required for caspase activation and induction of apoptosis by bisphosphonate drugs.
    Coxon FP; Benford HL; Russell RG; Rogers MJ
    Mol Pharmacol; 1998 Oct; 54(4):631-8. PubMed ID: 9765505
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298.
    Coxon FP; Helfrich MH; Van't Hof R; Sebti S; Ralston SH; Hamilton A; Rogers MJ
    J Bone Miner Res; 2000 Aug; 15(8):1467-76. PubMed ID: 10934645
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bisphosphonates: from the laboratory to the clinic and back again.
    Russell RG; Rogers MJ
    Bone; 1999 Jul; 25(1):97-106. PubMed ID: 10423031
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of pamidronate on the stimulation of macrophage TNF-alpha release by ultra-high-molecular-weight polyethylene particles: a role for apoptosis.
    Huk OL; Zukor DJ; Antoniou J; Petit A
    J Orthop Res; 2003 Jan; 21(1):81-7. PubMed ID: 12507583
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Relative binding affinities of bisphosphonates for human bone and relationship to antiresorptive efficacy.
    Leu CT; Luegmayr E; Freedman LP; Rodan GA; Reszka AA
    Bone; 2006 May; 38(5):628-36. PubMed ID: 16185944
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bisphosphonates act directly on the osteoclast to induce caspase cleavage of mst1 kinase during apoptosis. A link between inhibition of the mevalonate pathway and regulation of an apoptosis-promoting kinase.
    Reszka AA; Halasy-Nagy JM; Masarachia PJ; Rodan GA
    J Biol Chem; 1999 Dec; 274(49):34967-73. PubMed ID: 10574973
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of protein prenylation by bisphosphonates causes sustained activation of Rac, Cdc42, and Rho GTPases.
    Dunford JE; Rogers MJ; Ebetino FH; Phipps RJ; Coxon FP
    J Bone Miner Res; 2006 May; 21(5):684-94. PubMed ID: 16734383
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bisphosphonates induce apoptosis of stromal tumor cells in giant cell tumor of bone.
    Cheng YY; Huang L; Lee KM; Xu JK; Zheng MH; Kumta SM
    Calcif Tissue Int; 2004 Jul; 75(1):71-7. PubMed ID: 15037971
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antitumor effects of bisphosphonates.
    Green JR
    Cancer; 2003 Feb; 97(3 Suppl):840-7. PubMed ID: 12548584
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Breast cancer cells inhibit spontaneous and bisphosphonate-induced osteoclast apoptosis.
    Hussein O; Tiedemann K; Komarova SV
    Bone; 2011 Feb; 48(2):202-11. PubMed ID: 20849994
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis.
    Frith JC; Mönkkönen J; Auriola S; Mönkkönen H; Rogers MJ
    Arthritis Rheum; 2001 Sep; 44(9):2201-10. PubMed ID: 11592386
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo.
    Hughes DE; Wright KR; Uy HL; Sasaki A; Yoneda T; Roodman GD; Mundy GR; Boyce BF
    J Bone Miner Res; 1995 Oct; 10(10):1478-87. PubMed ID: 8686503
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro.
    Frith JC; Mönkkönen J; Blackburn GM; Russell RG; Rogers MJ
    J Bone Miner Res; 1997 Sep; 12(9):1358-67. PubMed ID: 9286751
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.