141 related articles for article (PubMed ID: 8895494)
1. Benzo[c]phenanthrene is activated to DNA-binding diol epoxides in the human mammary carcinoma cell line MCF-7 but only limited activation occurs in mouse skin.
Einolf HJ; Amin S; Yagi H; Jerina DM; Baird WM
Carcinogenesis; 1996 Oct; 17(10):2237-44. PubMed ID: 8895494
[TBL] [Abstract][Full Text] [Related]
2. Role of cytochrome P450 enzyme induction in the metabolic activation of benzo[c]phenanthrene in human cell lines and mouse epidermis.
Einolf HJ; Story WT; Marcus CB; Larsen MC; Jefcoate CR; Greenlee WF; Yagi H; Jerina DM; Amin S; Park SS; Gelboin HV; Baird WM
Chem Res Toxicol; 1997 May; 10(5):609-17. PubMed ID: 9168260
[TBL] [Abstract][Full Text] [Related]
3. Stereochemical specificity in the metabolic activation of benzo(c)phenanthrene to metabolites that covalently bind to DNA in rodent embryo cell cultures.
Pruess-Schwartz D; Baird WM; Yagi H; Jerina DM; Pigott MA; Dipple A
Cancer Res; 1987 Aug; 47(15):4032-7. PubMed ID: 3607748
[TBL] [Abstract][Full Text] [Related]
4. Covalent DNA adducts formed by benzo[c]chrysene in mouse epidermis and by benzo[c]chrysene fjord-region diol epoxides reacted with DNA and polynucleotides.
Giles AS; Seidel A; Phillips DH
Chem Res Toxicol; 1997 Nov; 10(11):1275-84. PubMed ID: 9403182
[TBL] [Abstract][Full Text] [Related]
5. Reactivity and tumorigenicity of bay-region diol epoxides derived from polycyclic aromatic hydrocarbons.
Jerina DM; Sayer JM; Agarwal SK; Yagi H; Levin W; Wood AW; Conney AH; Pruess-Schwartz D; Baird WM; Pigott MA
Adv Exp Med Biol; 1986; 197():11-30. PubMed ID: 3490131
[TBL] [Abstract][Full Text] [Related]
6. Dose-dependent differences in the mutational profiles of (-)-(1R,2S,3S,4R)-3,4-dihydroxy-1, 2-epoxy-1,2,3,4-tetrahydrobenzo[c]phenanthrene and its less carcinogenic enantiomer.
Wei SJ; Chang RL; Cui XX; Merkler KA; Wong CQ; Yagi H; Jerina DM; Conney AH
Cancer Res; 1996 Aug; 56(16):3695-703. PubMed ID: 8706010
[TBL] [Abstract][Full Text] [Related]
7. High selectivity of polyclonal antibodies against DNA modified by diastereomeric benzo[c]phenanthrene-3,4-diol-1,2-epoxides.
Butch ER; Lau HH; Shaw KL; Smolarek TA; Schmerold I; Anderson JN; Baird WM; Yagi H; Jerina DM
Carcinogenesis; 1992 May; 13(5):895-9. PubMed ID: 1587005
[TBL] [Abstract][Full Text] [Related]
8. Stereoselective activation of dibenzo[a,l]pyrene to (-)-anti (11R,12S,13S,14R)- and (+)-syn(11S,12R,13S,14R)-11,12-diol-13,14-epoxides which bind extensively to deoxyadenosine residues of DNA in the human mammary carcinoma cell line MCF-7.
Ralston SL; Seidel A; Luch A; Platt KL; Baird WM
Carcinogenesis; 1995 Dec; 16(12):2899-907. PubMed ID: 8603462
[TBL] [Abstract][Full Text] [Related]
9. Cyclohexene ring and Fjord region twist inversion in stereoisomeric DNA adducts of enantiomeric benzo[c]phenanthrene diol epoxides.
Wu M; Yan S; Patel DJ; Geacintov NE; Broyde S
Chem Res Toxicol; 2001 Dec; 14(12):1629-42. PubMed ID: 11743746
[TBL] [Abstract][Full Text] [Related]
10. Metabolic activation of 4H-cyclopenta[def]chrysene in human mammary carcinoma MCF-7 cell cultures.
Agarwal R; Coffing SL; Baird WM; Harvey RG; Dipple A
Chem Res Toxicol; 1999 May; 12(5):437-41. PubMed ID: 10328754
[TBL] [Abstract][Full Text] [Related]
11. Covalent DNA adducts formed in mouse epidermis by benzo[g]chrysene.
Giles AS; Seidel A; Phillips DH
Carcinogenesis; 1996 Jun; 17(6):1331-6. PubMed ID: 8681451
[TBL] [Abstract][Full Text] [Related]
12. Tumorigenicity of four optically active bay-region 3,4-diol 1, 2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine on mouse skin and in newborn mice.
Chang RL; Wood AW; Kumar S; Lehr RE; Shirai N; Jerina DM; Conney AH
Carcinogenesis; 2000 Nov; 21(11):1997-2003. PubMed ID: 11062160
[TBL] [Abstract][Full Text] [Related]
13. Stereoselectivity of activation of 7,12-dimethylbenz[a]anthracene- 3,4-dihydrodiol to the anti-diol epoxide metabolite in a human mammary carcinoma MCF-7 cell-mediated V79 cell mutation assay.
Lau HH; Coffing SL; Lee H; Harvey RG; Baird WM
Chem Res Toxicol; 1995; 8(7):970-8. PubMed ID: 8555413
[TBL] [Abstract][Full Text] [Related]
14. Synthetic, crystallographic, computational, and biological studies of 1,4-difluorobenzo[c]phenanthrene and its metabolites.
Bae S; Mah H; Chaturvedi S; Jeknic TM; Baird WM; Katz AK; Carrell HL; Glusker JP; Okazaki T; Laali KK; Zajc B; Lakshman MK
J Org Chem; 2007 Sep; 72(20):7625-33. PubMed ID: 17764198
[TBL] [Abstract][Full Text] [Related]
15. In vitro reaction with DNA of the fjord-region diol epoxides of benzo[g]chrysene and benzo[c]phenanthrene as studied by 32P-postlabeling.
Giles AS; Seidel A; Phillips DH
Chem Res Toxicol; 1995 Jun; 8(4):591-9. PubMed ID: 7548740
[TBL] [Abstract][Full Text] [Related]
16. Enhancing effect of a bay region methyl group on tumorigenicity in newborn mice and mouse skin of enantiomeric bay region diol epoxides formed stereoselectively from methylchrysenes in mouse epidermis.
Hecht SS; Amin S; Huie K; Melikian AA; Harvey RG
Cancer Res; 1987 Oct; 47(20):5310-5. PubMed ID: 3652037
[TBL] [Abstract][Full Text] [Related]
17. 5-Methylchrysene metabolism in mouse epidermis in vivo, diol epoxide--DNA adduct persistence, and diol epoxide reactivity with DNA as potential factors influencing the predominance of 5-methylchrysene-1,2-diol-3,4-epoxide--DNA adducts in mouse epidermis.
Melikian AA; LaVoie EJ; Hecht SS; Hoffmann D
Carcinogenesis; 1983; 4(7):843-9. PubMed ID: 6872139
[TBL] [Abstract][Full Text] [Related]
18. Regio- and stereoselectivity in the metabolism of benzo[c]phenanthrene mediated by genetically engineered V79 Chinese hamster cells expressing rat and human cytochromes P450.
Seidel A; Soballa VJ; Raab G; Frank H; Greim H; Grimmer G; Jacob J; Doehmer J
Environ Toxicol Pharmacol; 1998 May; 5(3):179-96. PubMed ID: 21781864
[TBL] [Abstract][Full Text] [Related]
19. Stereoselective activation of dibenzo[a,l]pyrene and its trans-11,12-dihydrodiol to fjord region 11,12-diol 13,14-epoxides in a human mammary carcinoma MCF-7 cell-mediated V79 cell mutation assay.
Ralston SL; Coffing SL; Seidel A; Luch A; Platt KL; Baird WM
Chem Res Toxicol; 1997 Jun; 10(6):687-93. PubMed ID: 9208176
[TBL] [Abstract][Full Text] [Related]
20. Direct synthesis and characterization of site-specific adenosyl adducts derived from the binding of a 3,4-dihydroxy-1,2-epoxybenzo[c]phenanthrene stereoisomer to an 11-mer oligodeoxyribonucleotide.
Laryea A; Cosman M; Lin JM; Liu T; Agarwal R; Smirnov S; Amin S; Harvey RG; Dipple A; Geacintov NE
Chem Res Toxicol; 1995; 8(3):444-54. PubMed ID: 7578932
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
