BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 8901913)

  • 1. A physiological toxicokinetic model for 1,3-butadiene in rodents and man: blood concentrations of 1,3-butadiene, its metabolically formed epoxides, and of haemoglobin adducts--relevance of glutathione depletion.
    Csanády GA; Kreuzer PE; Baur C; Filser JG
    Toxicology; 1996 Oct; 113(1-3):300-5. PubMed ID: 8901913
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolation.
    Johanson G; Filser JG
    Arch Toxicol; 1993; 67(3):151-63. PubMed ID: 8494494
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation.
    Himmelstein MW; Turner MJ; Asgharian B; Bond JA
    Carcinogenesis; 1994 Aug; 15(8):1479-86. PubMed ID: 8055623
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice.
    Csanády GA; Guengerich FP; Bond JA
    Carcinogenesis; 1992 Jul; 13(7):1143-53. PubMed ID: 1638680
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Physiologically based pharmacokinetic modeling of 1,3-butadiene, 1,2-epoxy-3-butene, and 1,2:3,4-diepoxybutane toxicokinetics in mice and rats.
    Sweeney LM; Schlosser PM; Medinsky MA; Bond JA
    Carcinogenesis; 1997 Apr; 18(4):611-25. PubMed ID: 9111190
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PBPK model for butadiene metabolism to epoxides: quantitative species differences in metabolism.
    Johanson G; Filser JG
    Toxicology; 1996 Oct; 113(1-3):40-7. PubMed ID: 8901881
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolism of 1,3-butadiene: inhalation pharmacokinetics and tissue dosimetry of butadiene epoxides in rats and mice.
    Himmelstein MW; Turner MJ; Asgharian B; Bond JA
    Toxicology; 1996 Oct; 113(1-3):306-9. PubMed ID: 8901914
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glutathione conjugation of 1,2:3,4- diepoxybutane in human liver and rat and mouse liver and lung in vitro.
    Boogaard PJ; Sumner SC; Bond JA
    Toxicol Appl Pharmacol; 1996 Feb; 136(2):307-16. PubMed ID: 8619238
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Research strategy for assessing target tissue dosimetry of 1,3-butadiene in laboratory animals and humans.
    Bond JA; Csanády GA; Leavens T; Medinsky MA
    IARC Sci Publ; 1993; (127):45-55. PubMed ID: 8070886
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of the structure of a toxicokinetic model of butadiene inhalation exposure on computed production of carcinogenic intermediates.
    Kohn MC; Melnick RL
    Toxicology; 1996 Oct; 113(1-3):31-9. PubMed ID: 8901880
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High concentrations of butadiene epoxides in livers and lungs of mice compared to rats exposed to 1,3-butadiene.
    Himmelstein MW; Asgharian B; Bond JA
    Toxicol Appl Pharmacol; 1995 Jun; 132(2):281-8. PubMed ID: 7785055
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stereochemical aspects of the conjugation of epoxide metabolites of butadiene with glutathione in rat liver cytosol and freshly isolated rat hepatocytes.
    Nieusma JL; Claffey DJ; Ruth JA; Ross D
    Toxicol Sci; 1998 Jun; 43(2):102-9. PubMed ID: 9710951
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Disposition of butadiene epoxides in Sprague-Dawley rats.
    Valentine JL; Boogaard PJ; Sweeney LM; Turner MJ; Bond JA; Medinsky MA
    Chem Biol Interact; 1997 May; 104(2-3):103-15. PubMed ID: 9212778
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes.
    Seaton MJ; Follansbee MH; Bond JA
    Carcinogenesis; 1995 Oct; 16(10):2287-93. PubMed ID: 7586124
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach.
    Motwani HV; Törnqvist M
    Toxicol Appl Pharmacol; 2014 Dec; 281(3):276-84. PubMed ID: 25448046
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolism of butadiene by mice, rats, and humans: a comparison of physiologically based toxicokinetic model predictions and experimental data.
    Bond JA; Himmelstein MW; Seaton M; Boogaard P; Medinsky MA
    Toxicology; 1996 Oct; 113(1-3):48-54. PubMed ID: 8901882
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA adducts in rats and mice following exposure to [4-14C]-1,2-epoxy-3-butene and to [2,3-14C]-1,3-butadiene.
    Boogaard PJ; de Kloe KP; Booth ED; Watson WP
    Chem Biol Interact; 2004 Jun; 148(1-2):69-92. PubMed ID: 15223358
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genotoxicity of 1,3-butadiene and its epoxy intermediates.
    Walker VE; Walker DM; Meng Q; McDonald JD; Scott BR; Seilkop SK; Claffey DJ; Upton PB; Powley MW; Swenberg JA; Henderson RF;
    Res Rep Health Eff Inst; 2009 Aug; (144):3-79. PubMed ID: 20017413
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Haemoglobin adducts of epoxybutanediol from exposure to 1,3-butadiene or butadiene epoxides.
    Pérez HL; Lähdetie J; Landin H; Kilpeläinen I; Koivisto P; Peltonen K; Osterman-Golkar S
    Chem Biol Interact; 1997 Aug; 105(3):181-98. PubMed ID: 9291996
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 1,2:3,4-Diepoxybutane in blood of male B6C3F1 mice and male Sprague-Dawley rats exposed to 1,3-butadiene.
    Csanády GA; Steinhoff R; Riester MB; Semder B; Pütz C; Li Q; Richter N; Kessler W; Klein D; Filser JG
    Toxicol Lett; 2011 Dec; 207(3):286-90. PubMed ID: 21983653
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.