BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1183 related articles for article (PubMed ID: 8913503)

  • 1. In vitro and in vivo antitumor activity of a novel nucleoside, 4'-thio-2'-deoxy-2'-methylidenecytidine.
    Miura S; Tanaka M; Yoshimura Y; Satoh H; Sakata S; Machida H; Matsuda A; Sasaki T
    Biol Pharm Bull; 1996 Oct; 19(10):1311-5. PubMed ID: 8913503
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High susceptibility of human cancer xenografts with higher levels of cytidine deaminase to a 2'-deoxycytidine antimetabolite, 2'-deoxy-2'-methylidenecytidine.
    Miwa M; Eda H; Ura M; Ouchi KF; Keith DD; Foley LH; Ishitsuka H
    Clin Cancer Res; 1998 Feb; 4(2):493-7. PubMed ID: 9516941
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antitumor activity of 2'-deoxy-2'-methylidenecytidine, a new 2'-deoxycytidine derivative.
    Yamagami K; Fujii A; Arita M; Okumoto T; Sakata S; Matsuda A; Ueda T; Sasaki T
    Cancer Res; 1991 May; 51(9):2319-23. PubMed ID: 2015596
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The antiproliferative activity of DMDC is modulated by inhibition of cytidine deaminase.
    Eda H; Ura M; F-Ouchi K; Tanaka Y; Miwa M; Ishitsuka H
    Cancer Res; 1998 Mar; 58(6):1165-9. PubMed ID: 9515801
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nucleosides and nucleotides. 97. Synthesis of new broad spectrum antineoplastic nucleosides, 2'-deoxy-2'-methylidenecytidine (DMDC) and its derivatives.
    Matsuda A; Takenuki K; Tanaka M; Sasaki T; Ueda T
    J Med Chem; 1991 Feb; 34(2):812-9. PubMed ID: 1995905
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antitumor activity of a novel orally effective nucleoside, 1-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)cytosine.
    Miura S; Yoshimura Y; Endo M; Machida H; Matsuda A; Tanaka M; Sasaki T
    Cancer Lett; 1998 Jul; 129(1):103-10. PubMed ID: 9714341
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The relationship between the antitumor activity and the ribonucleotide reductase inhibitory activity of (E)-2'-deoxy-2'-(fluoromethylene) cytidine, MDL 101,731.
    Kanazawa J; Takahashi T; Akinaga S; Tamaoki T; Okabe M
    Anticancer Drugs; 1998 Aug; 9(7):653-7. PubMed ID: 9773810
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolism of 4'-thio-beta-D-arabinofuranosylcytosine in CEM cells.
    Parker WB; Shaddix SC; Rose LM; Waud WR; Shewach DS; Tiwari KN; Secrist JA
    Biochem Pharmacol; 2000 Dec; 60(12):1925-32. PubMed ID: 11108809
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of differentiation of acute promyelocytic leukemia cells by a cytidine deaminase-resistant analogue of 1-beta-D-arabinofuranosylcytosine, 1-(2-deoxy-2-methylene-beta-D-erythro-pentofuranosyl)cytidine.
    Niitsu N; Ishii Y; Matsuda A; Honma Y
    Cancer Res; 2001 Jan; 61(1):178-85. PubMed ID: 11196157
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of 1-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)cytosine with gemcitabine in its antitumor activity.
    Miura S; Yoshimura Y; Endo M; Satoh H; Machida H; Sasaki T
    Cancer Lett; 1999 Oct; 144(2):177-82. PubMed ID: 10529018
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel DNA methyltransferase-1 (DNMT1) depleting anticancer nucleosides, 4'-thio-2'-deoxycytidine and 5-aza-4'-thio-2'-deoxycytidine.
    Thottassery JV; Sambandam V; Allan PW; Maddry JA; Maxuitenko YY; Tiwari K; Hollingshead M; Parker WB
    Cancer Chemother Pharmacol; 2014 Aug; 74(2):291-302. PubMed ID: 24908436
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and anticancer and antiviral activities of various 2'- and 3'-methylidene-substituted nucleoside analogues and crystal structure of 2'-deoxy-2'-methylidenecytidine hydrochloride.
    Lin TS; Luo MZ; Liu MC; Clarke-Katzenburg RH; Cheng YC; Prusoff WH; Mancini WR; Birnbaum GI; Gabe EJ; Giziewicz J
    J Med Chem; 1991 Aug; 34(8):2607-15. PubMed ID: 1652024
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nucleosides and nucleotides. 176. 2'-Deoxy-2'-hydroxylaminocytidine: a new antitumor nucleoside that inhibits DNA synthesis although it has a ribonucleoside structure.
    Ogawa A; Shuto S; Inanami O; Kuwabara M; Tanaka M; Sasaki T; Matsuda A
    Bioorg Med Chem Lett; 1998 Jul; 8(14):1913-8. PubMed ID: 9873458
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clinical pharmacokinetics of 2'-deoxy-2'-methylidenecytidine (DMDC), a deoxycytidine analogue antineoplastic agent.
    Brindley CJ; Morrison R; Gordon RJ; Devlin AJ; van der Gaast A; Verweij L; Funaki T
    Clin Pharmacokinet; 2000 Jun; 38(6):475-91. PubMed ID: 10885585
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of 4'-Thionucleosides as Antitumor and Antiviral Agents.
    Yoshimura Y; Saito Y; Natori Y; Wakamatsu H
    Chem Pharm Bull (Tokyo); 2018; 66(2):139-146. PubMed ID: 29386464
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antitumor activity of a novel nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine (CNDAC) against murine and human tumors.
    Tanaka M; Matsuda A; Terao T; Sasaki T
    Cancer Lett; 1992 May; 64(1):67-74. PubMed ID: 1596880
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nucleosides and nucleotides. 180. Synthesis and antitumor activity of nucleosides that have a hydroxylamino group instead of a hydroxyl group at the 2'- or 3'-position of the sugar moiety.
    Ogawa A; Tanaka M; Sasaki T; Matsuda A
    J Med Chem; 1998 Dec; 41(25):5094-107. PubMed ID: 9836625
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phase I trial of oral 2'-deoxy-2'-methylidenecytidine: on a daily x 14-day schedule.
    Masuda N; Matsui K; Yamamoto N; Nogami T; Nakagawa K; Negoro S; Takeda K; Takifuji N; Yamada M; Kudoh S; Okuda T; Nemoto S; Ogawa K; Myobudani H; Nihira S; Fukuoka M
    Clin Cancer Res; 2000 Jun; 6(6):2288-94. PubMed ID: 10873079
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and antineoplastic activity of 2'-deoxy-2'-methylidenecytidine.
    Takenuki K; Matsuda A; Ueda T; Sasaki T; Fujii A; Yamagami K
    J Med Chem; 1988 Jun; 31(6):1063-4. PubMed ID: 3373480
    [No Abstract]   [Full Text] [Related]  

  • 20. A novel synthesis of antineoplastic 4'-thionucleosides using D-glucose as a chiral synthon.
    Yoshimura Y; Satoh H; Watanabe M; Sakata S; Miura S; Tanaka M; Sasaki T; Matsuda A
    Nucleic Acids Symp Ser; 1995; (34):161-2. PubMed ID: 8841602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 60.