BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 8917701)

  • 1. Comparative cytotoxicity of 14 novel selenocysteine se-conjugates in rat renal proximal tubular cells.
    Andreadou I; van de Water B; Commandeur JN; Nagelkerke FJ; Vermeulen NP
    Toxicol Appl Pharmacol; 1996 Nov; 141(1):278-87. PubMed ID: 8917701
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of novel Se-substituted selenocysteine derivatives as potential kidney selective prodrugs of biologically active selenol compounds: evaluation of kinetics of beta-elimination reactions in rat renal cytosol.
    Andreadou I; Menge WM; Commandeur JN; Worthington EA; Vermeulen NP
    J Med Chem; 1996 May; 39(10):2040-6. PubMed ID: 8642562
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bioactivation of selenocysteine Se-conjugates by a highly purified rat renal cysteine conjugate beta-lyase/glutamine transaminase K.
    Commandeur JN; Andreadou I; Rooseboom M; Out M; de Leur LJ; Groot E; Vermeulen NP
    J Pharmacol Exp Ther; 2000 Aug; 294(2):753-61. PubMed ID: 10900257
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of the kinetics of beta-elimination reactions of selenocysteine Se-conjugates in human renal cytosol: possible implications for the use as kidney selective prodrugs.
    Rooseboom M; Vermeulen NP; Andreadou I; Commandeur JN
    J Pharmacol Exp Ther; 2000 Aug; 294(2):762-9. PubMed ID: 10900258
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparative study on the bioactivation mechanisms and cytotoxicity of Te-phenyl-L-tellurocysteine, Se-phenyl-L-selenocysteine, and S-phenyl-L-cysteine.
    Rooseboom M; Vermeulen NP; Durgut F; Commandeur JN
    Chem Res Toxicol; 2002 Dec; 15(12):1610-8. PubMed ID: 12482244
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Roles of cysteine conjugate beta-lyase and S-oxidase in nephrotoxicity: studies with S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine sulfoxide.
    Lash LH; Sausen PJ; Duescher RJ; Cooley AJ; Elfarra AA
    J Pharmacol Exp Ther; 1994 Apr; 269(1):374-83. PubMed ID: 8169843
    [TBL] [Abstract][Full Text] [Related]  

  • 7. S-[(1 and 2)-phenyl-2-hydroxyethyl]-cysteine-induced cytotoxicity to rat renal proximal tubules.
    Chakrabarti SK; Denniel C
    Toxicol Appl Pharmacol; 1996 Apr; 137(2):285-94. PubMed ID: 8661354
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells.
    McGoldrick TA; Lock EA; Rodilla V; Hawksworth GM
    Arch Toxicol; 2003 Jul; 77(7):365-70. PubMed ID: 12700887
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Beta-lyase-dependent attenuation of cisplatin-mediated toxicity by selenocysteine Se-conjugates in renal tubular cell lines.
    Rooseboom M; Schaaf G; Commandeur JN; Vermeulen NP; Fink-Gremmels J
    J Pharmacol Exp Ther; 2002 Jun; 301(3):884-92. PubMed ID: 12023515
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Uptake of nephrotoxic S-conjugates by isolated rat renal proximal tubular cells.
    Lash LH; Anders MW
    J Pharmacol Exp Ther; 1989 Feb; 248(2):531-7. PubMed ID: 2918469
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine-induced apoptosis.
    Chen Y; Cai J; Anders MW; Stevens JL; Jones DP
    Toxicol Appl Pharmacol; 2001 Feb; 170(3):172-80. PubMed ID: 11162782
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alpha-ketoacids stimulate rat renal cysteine conjugate beta-lyase activity and potentiate the cytotoxicity of S-(1,2-dichlorovinyl)-L-cysteine.
    Elfarra AA; Lash LH; Anders MW
    Mol Pharmacol; 1987 Feb; 31(2):208-12. PubMed ID: 3807895
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative cytotoxicity of N-substituted N'-(4-imidazole-ethyl)thiourea in precision-cut rat liver slices.
    Onderwater RC; Commandeur JN; Vermeulen NP
    Toxicology; 2004 Apr; 197(2):81-91. PubMed ID: 15003319
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Atractyloside nephrotoxicity: in vitro studies with suspensions of rat renal fragments and precision-cut cortical slices.
    Obatomi DK; Bach PH
    In Vitr Mol Toxicol; 2000; 13(1):25-36. PubMed ID: 10900405
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Roles of necrosis, Apoptosis, and mitochondrial dysfunction in S-(1,2-dichlorovinyl)-L-cysteine sulfoxide-induced cytotoxicity in primary cultures of human renal proximal tubular cells.
    Lash LH; Putt DA; Hueni SE; Krause RJ; Elfarra AA
    J Pharmacol Exp Ther; 2003 Jun; 305(3):1163-72. PubMed ID: 12626654
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bioactivation of chemopreventive selenocysteine Se-conjugates and related amino acids by amino acid oxidases novel route of metabolism of selenoamino acids.
    Rooseboom M; Vermeulen NP; van Hemert N; Commandeur JN
    Chem Res Toxicol; 2001 Aug; 14(8):996-1005. PubMed ID: 11511173
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sulfoxidation of mercapturic acids derived from tri- and tetrachloroethene by cytochromes P450 3A: a bioactivation reaction in addition to deacetylation and cysteine conjugate beta-lyase mediated cleavage.
    Werner M; Birner G; Dekant W
    Chem Res Toxicol; 1996; 9(1):41-9. PubMed ID: 8924615
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pentachlorobutadienyl-L-cysteine (PCBC) toxicity: the importance of mitochondrial dysfunction.
    Groves CE; Schnellmann RG; Sokol PP; Steffens TG; Lock EA
    J Biochem Toxicol; 1991; 6(4):253-60. PubMed ID: 1774769
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tissue distribution of cytosolic beta-elimination reactions of selenocysteine Se-conjugates in rat and human.
    Rooseboom M; Vermeulen NP; Groot EJ; Commandeur JN
    Chem Biol Interact; 2002 Aug; 140(3):243-64. PubMed ID: 12204580
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cysteine conjugate beta-lyase-dependent biotransformation of the cysteine S-conjugates of the sevoflurane degradation product 2-(fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (compound A).
    Iyer RA; Anders MW
    Chem Res Toxicol; 1997 Jul; 10(7):811-9. PubMed ID: 9250416
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.