410 related articles for article (PubMed ID: 8918938)
1. Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site.
Schier R; McCall A; Adams GP; Marshall KW; Merritt H; Yim M; Crawford RS; Weiner LM; Marks C; Marks JD
J Mol Biol; 1996 Nov; 263(4):551-67. PubMed ID: 8918938
[TBL] [Abstract][Full Text] [Related]
2. Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection.
Schier R; Bye J; Apell G; McCall A; Adams GP; Malmqvist M; Weiner LM; Marks JD
J Mol Biol; 1996 Jan; 255(1):28-43. PubMed ID: 8568873
[TBL] [Abstract][Full Text] [Related]
3. Targeting of bivalent anti-ErbB2 diabody antibody fragments to tumor cells is independent of the intrinsic antibody affinity.
Nielsen UB; Adams GP; Weiner LM; Marks JD
Cancer Res; 2000 Nov; 60(22):6434-40. PubMed ID: 11103810
[TBL] [Abstract][Full Text] [Related]
4. Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.
Finlay WJ; Cunningham O; Lambert MA; Darmanin-Sheehan A; Liu X; Fennell BJ; Mahon CM; Cummins E; Wade JM; O'Sullivan CM; Tan XY; Piche N; Pittman DD; Paulsen J; Tchistiakova L; Kodangattil S; Gill D; Hufton SE
J Mol Biol; 2009 May; 388(3):541-58. PubMed ID: 19285987
[TBL] [Abstract][Full Text] [Related]
5. Anti-estradiol-17beta single-chain Fv fragments: Generation, characterization, gene randomization, and optimized phage display.
Kobayashi N; Kato Y; Oyama H; Taga S; Niwa T; Sun P; Ohtoyo M; Goto J
Steroids; 2008 Dec; 73(14):1485-99. PubMed ID: 18824188
[TBL] [Abstract][Full Text] [Related]
6. Efficient in vitro affinity maturation of phage antibodies using BIAcore guided selections.
Schier R; Marks JD
Hum Antibodies Hybridomas; 1996; 7(3):97-105. PubMed ID: 9057057
[TBL] [Abstract][Full Text] [Related]
7. Selection, characterization and x-ray structure of anti-ampicillin single-chain Fv fragments from phage-displayed murine antibody libraries.
Burmester J; Spinelli S; Pugliese L; Krebber A; Honegger A; Jung S; Schimmele B; Cambillau C; Plückthun A
J Mol Biol; 2001 Jun; 309(3):671-85. PubMed ID: 11397088
[TBL] [Abstract][Full Text] [Related]
8. Humanization of a highly stable single-chain antibody by structure-based antigen-binding site grafting.
Villani ME; Morea V; Consalvi V; Chiaraluce R; Desiderio A; Benvenuto E; Donini M
Mol Immunol; 2008 May; 45(9):2474-85. PubMed ID: 18313757
[TBL] [Abstract][Full Text] [Related]
9. Critical interactions in binding antibody NC41 to influenza N9 neuraminidase: amino acid contacts on the antibody heavy chain.
Pruett PS; Air GM
Biochemistry; 1998 Jul; 37(30):10660-70. PubMed ID: 9692956
[TBL] [Abstract][Full Text] [Related]
10. Improvement of anti-Burkholderia mouse monoclonal antibody from various phage-displayed single-chain antibody libraries.
Kim HS; Lo SC; Wear DJ; Stojadinovic A; Weina PJ; Izadjoo MJ
J Immunol Methods; 2011 Sep; 372(1-2):146-61. PubMed ID: 21787781
[TBL] [Abstract][Full Text] [Related]
11. Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent.
Beiboer SH; Reurs A; Roovers RC; Arends JW; Whitelegg NR; Rees AR; Hoogenboom HR
J Mol Biol; 2000 Feb; 296(3):833-49. PubMed ID: 10677285
[TBL] [Abstract][Full Text] [Related]
12. Human immunoglobulin repertoires against tetanus toxoid contain a large and diverse fraction of high-affinity promiscuous V(H) genes.
de Kruif J; Kramer A; Visser T; Clements C; Nijhuis R; Cox F; van der Zande V; Smit R; Pinto D; Throsby M; Logtenberg T
J Mol Biol; 2009 Apr; 387(3):548-58. PubMed ID: 19361421
[TBL] [Abstract][Full Text] [Related]
13. Enhancement of scFv fragment reactivity with target antigens in binding assays following mixing with anti-tag monoclonal antibodies.
Wang X; Campoli M; Ko E; Luo W; Ferrone S
J Immunol Methods; 2004 Nov; 294(1-2):23-35. PubMed ID: 15604013
[TBL] [Abstract][Full Text] [Related]
14. A semi-synthetic repertoire of intrinsically stable antibody fragments derived from a single-framework scaffold.
Desiderio A; Franconi R; Lopez M; Villani ME; Viti F; Chiaraluce R; Consalvi V; Neri D; Benvenuto E
J Mol Biol; 2001 Jul; 310(3):603-15. PubMed ID: 11439027
[TBL] [Abstract][Full Text] [Related]
15. Two-step in vitro antibody affinity maturation enables estradiol-17beta assays with more than 10-fold higher sensitivity.
Kobayashi N; Oyama H; Kato Y; Goto J; Söderlind E; Borrebaeck CA
Anal Chem; 2010 Feb; 82(3):1027-38. PubMed ID: 20047279
[TBL] [Abstract][Full Text] [Related]
16. Critical binding site amino acids of anti-Z-DNA single chain Fv molecules. Role of heavy and light chain CDR3 and relationship to autoantibody activity.
Polymenis M; Stollar BD
J Immunol; 1994 Jun; 152(11):5318-29. PubMed ID: 8189049
[TBL] [Abstract][Full Text] [Related]
17. Directed evolution, phage display and combination of evolved mutants: a strategy to recover the neutralization properties of the scFv version of BCF2 a neutralizing monoclonal antibody specific to scorpion toxin Cn2.
Juárez-González VR; Riaño-Umbarila L; Quintero-Hernández V; Olamendi-Portugal T; Ortiz-León M; Ortíz E; Possani LD; Becerril B
J Mol Biol; 2005 Mar; 346(5):1287-97. PubMed ID: 15713481
[TBL] [Abstract][Full Text] [Related]
18. A general method for greatly improving the affinity of antibodies by using combinatorial libraries.
Rajpal A; Beyaz N; Haber L; Cappuccilli G; Yee H; Bhatt RR; Takeuchi T; Lerner RA; Crea R
Proc Natl Acad Sci U S A; 2005 Jun; 102(24):8466-71. PubMed ID: 15939870
[TBL] [Abstract][Full Text] [Related]
19. High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules.
Adams GP; Schier R; McCall AM; Simmons HH; Horak EM; Alpaugh RK; Marks JD; Weiner LM
Cancer Res; 2001 Jun; 61(12):4750-5. PubMed ID: 11406547
[TBL] [Abstract][Full Text] [Related]
20. Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies.
Daugherty PS; Chen G; Iverson BL; Georgiou G
Proc Natl Acad Sci U S A; 2000 Feb; 97(5):2029-34. PubMed ID: 10688877
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]