244 related articles for article (PubMed ID: 8925840)
1. Functional expression of a fragment of human dihydroorotate dehydrogenase by means of the baculovirus expression vector system, and kinetic investigation of the purified recombinant enzyme.
Knecht W; Bergjohann U; Gonski S; Kirschbaum B; Löffler M
Eur J Biochem; 1996 Aug; 240(1):292-301. PubMed ID: 8925840
[TBL] [Abstract][Full Text] [Related]
2. Rat dihydroorotate dehydrogenase: isolation of the recombinant enzyme from mitochondria of insect cells.
Knecht W; Altekruse D; Rotgeri A; Gonski S; Löffler M
Protein Expr Purif; 1997 Jun; 10(1):89-99. PubMed ID: 9179295
[TBL] [Abstract][Full Text] [Related]
3. Species-related inhibition of human and rat dihydroorotate dehydrogenase by immunosuppressive isoxazol and cinchoninic acid derivatives.
Knecht W; Löffler M
Biochem Pharmacol; 1998 Nov; 56(9):1259-64. PubMed ID: 9802339
[TBL] [Abstract][Full Text] [Related]
4. Expression, purification, and characterization of histidine-tagged rat and human flavoenzyme dihydroorotate dehydrogenase.
Bader B; Knecht W; Fries M; Löffler M
Protein Expr Purif; 1998 Aug; 13(3):414-22. PubMed ID: 9693067
[TBL] [Abstract][Full Text] [Related]
5. Recombinant expression of N-terminal truncated mutants of the membrane bound mouse, rat and human flavoenzyme dihydroorotate dehydrogenase. A versatile tool to rate inhibitor effects?
Ullrich A; Knecht W; Fries M; Löffler M
Eur J Biochem; 2001 Mar; 268(6):1861-8. PubMed ID: 11248707
[TBL] [Abstract][Full Text] [Related]
6. Kinetics of inhibition of human and rat dihydroorotate dehydrogenase by atovaquone, lawsone derivatives, brequinar sodium and polyporic acid.
Knecht W; Henseling J; Löffler M
Chem Biol Interact; 2000 Jan; 124(1):61-76. PubMed ID: 10658902
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of dihydroorotate dehydrogenase by the immunosuppressive agent leflunomide.
Greene S; Watanabe K; Braatz-Trulson J; Lou L
Biochem Pharmacol; 1995 Sep; 50(6):861-7. PubMed ID: 7575649
[TBL] [Abstract][Full Text] [Related]
8. Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity.
Baldwin J; Farajallah AM; Malmquist NA; Rathod PK; Phillips MA
J Biol Chem; 2002 Nov; 277(44):41827-34. PubMed ID: 12189151
[TBL] [Abstract][Full Text] [Related]
9. Structural and functional comparison of agents interfering with dihydroorotate, succinate and NADH oxidation of rat liver mitochondria.
Jöckel J; Wendt B; Löffler M
Biochem Pharmacol; 1998 Oct; 56(8):1053-60. PubMed ID: 9776318
[TBL] [Abstract][Full Text] [Related]
10. Expression and characterization of E. coli-produced soluble, functional human dihydroorotate dehydrogenase: a potential target for immunosuppression.
Neidhardt EA; Punreddy SR; McLean JE; Hedstrom L; Grossman TH
J Mol Microbiol Biotechnol; 1999 Aug; 1(1):183-8. PubMed ID: 10941801
[TBL] [Abstract][Full Text] [Related]
11. Recombinant human dihydroorotate dehydrogenase: expression, purification, and characterization of a catalytically functional truncated enzyme.
Copeland RA; Davis JP; Dowling RL; Lombardo D; Murphy KB; Patterson TA
Arch Biochem Biophys; 1995 Oct; 323(1):79-86. PubMed ID: 7487077
[TBL] [Abstract][Full Text] [Related]
12. Purification, characterization and localization of mitochondrial dihydroorotate dehydrogenase in Plasmodium falciparum, human malaria parasite.
Krungkrai J
Biochim Biophys Acta; 1995 Apr; 1243(3):351-60. PubMed ID: 7727509
[TBL] [Abstract][Full Text] [Related]
13. Anti-peptide immunoglobulins from rabbit and chicken eggs recognise recombinant human dihydroorotate dehydrogenase and a 44-kDa protein from rat liver mitochondria.
Knecht W; Köhler R; Minét M; Löffler M
Eur J Biochem; 1996 Mar; 236(2):609-13. PubMed ID: 8612635
[TBL] [Abstract][Full Text] [Related]
14. A second dihydroorotate dehydrogenase (Type A) of the human pathogen Enterococcus faecalis: expression, purification, and steady-state kinetic mechanism.
Marcinkeviciene J; Jiang W; Locke G; Kopcho LM; Rogers MJ; Copeland RA
Arch Biochem Biophys; 2000 May; 377(1):178-86. PubMed ID: 10775458
[TBL] [Abstract][Full Text] [Related]
15. The activity of Escherichia coli dihydroorotate dehydrogenase is dependent on a conserved loop identified by sequence homology, mutagenesis, and limited proteolysis.
Björnberg O; Grüner AC; Roepstorff P; Jensen KF
Biochemistry; 1999 Mar; 38(10):2899-908. PubMed ID: 10074342
[TBL] [Abstract][Full Text] [Related]
16. Porcine recombinant dihydropyrimidine dehydrogenase: comparison of the spectroscopic and catalytic properties of the wild-type and C671A mutant enzymes.
Rosenbaum K; Jahnke K; Curti B; Hagen WR; Schnackerz KD; Vanoni MA
Biochemistry; 1998 Dec; 37(50):17598-609. PubMed ID: 9860876
[TBL] [Abstract][Full Text] [Related]
17. Plant dihydroorotate dehydrogenase differs significantly in substrate specificity and inhibition from the animal enzymes.
Ullrich A; Knecht W; Piskur J; Löffler M
FEBS Lett; 2002 Oct; 529(2-3):346-50. PubMed ID: 12372626
[TBL] [Abstract][Full Text] [Related]
18. Dihydroorotate dehydrogenase is a high affinity binding protein for A77 1726 and mediator of a range of biological effects of the immunomodulatory compound.
Williamson RA; Yea CM; Robson PA; Curnock AP; Gadher S; Hambleton AB; Woodward K; Bruneau JM; Hambleton P; Moss D; Thomson TA; Spinella-Jaegle S; Morand P; Courtin O; Sautés C; Westwood R; Hercend T; Kuo EA; Ruuth E
J Biol Chem; 1995 Sep; 270(38):22467-72. PubMed ID: 7673235
[TBL] [Abstract][Full Text] [Related]
19. Drosophila melanogaster dihydroorotate dehydrogenase: the N-terminus is important for biological function in vivo but not for catalytic properties in vitro.
Löffler M; Knecht W; Rawls J; Ullrich A; Dietz C
Insect Biochem Mol Biol; 2002 Sep; 32(9):1159-69. PubMed ID: 12213251
[TBL] [Abstract][Full Text] [Related]
20. The immunosuppressive metabolite of leflunomide is a potent inhibitor of human dihydroorotate dehydrogenase.
Davis JP; Cain GA; Pitts WJ; Magolda RL; Copeland RA
Biochemistry; 1996 Jan; 35(4):1270-3. PubMed ID: 8573583
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]