These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 8931726)

  • 1. Inhibitors of bacterial signal peptidase: a series of 6-(substituted oxyethyl)penems.
    Allsop A; Brooks G; Edwards PD; Kaura AC; Southgate R
    J Antibiot (Tokyo); 1996 Sep; 49(9):921-8. PubMed ID: 8931726
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Penems as research tools to investigate the activity of E.coli leader peptidase.
    Perry CR; Ashby MJ; Elsmere SA
    Biochem Soc Trans; 1995 Nov; 23(4):548S. PubMed ID: 8654733
    [No Abstract]   [Full Text] [Related]  

  • 3. Synthesis and structure-activity relationships of novel pyrrolocarbazole lactam analogs as potent and cell-permeable inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1).
    Wells GJ; Bihovsky R; Hudkins RL; Ator MA; Husten J
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1151-5. PubMed ID: 16359865
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A serine and a lysine residue implicated in the catalytic mechanism of the Escherichia coli leader peptidase.
    Tschantz WR; Sung M; Delgado-Partin VM; Dalbey RE
    J Biol Chem; 1993 Dec; 268(36):27349-54. PubMed ID: 8262975
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor.
    Paetzel M; Dalbey RE; Strynadka NC
    Nature; 1998 Nov; 396(6707):186-90. PubMed ID: 9823901
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Monosubstituted γ-lactam and conformationally constrained 1,3-diaminopropan-2-ol transition-state isostere inhibitors of β-secretase (BACE).
    Boy KM; Guernon JM; Shi J; Toyn JH; Meredith JE; Barten DM; Burton CR; Albright CF; Marcinkeviciene J; Good AC; Tebben AJ; Muckelbauer JK; Camac DM; Lentz KA; Bronson JJ; Olson RE; Macor JE; Thompson LA
    Bioorg Med Chem Lett; 2011 Nov; 21(22):6916-24. PubMed ID: 21782431
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and biological activity of potent and selective inhibitors of mast cell tryptase.
    Hopkins CR; Czekaj M; Kaye SS; Gao Z; Pribish J; Pauls H; Liang G; Sides K; Cramer D; Cairns J; Luo Y; Lim HK; Vaz R; Rebello S; Maignan S; Dupuy A; Mathieu M; Levell J
    Bioorg Med Chem Lett; 2005 Jun; 15(11):2734-7. PubMed ID: 15911249
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Boronic ester-linked macrocyclic lipopeptides as serine protease inhibitors targeting Escherichia coli type I signal peptidase.
    Szałaj N; Lu L; Benediktsdottir A; Zamaratski E; Cao S; Olanders G; Hedgecock C; Karlén A; Erdélyi M; Hughes D; Mowbray SL; Brandt P
    Eur J Med Chem; 2018 Sep; 157():1346-1360. PubMed ID: 30196059
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, characterization and antibacterial activities of some new ferrocene-containing penems.
    Long B; He C; Yang Y; Xiang J
    Eur J Med Chem; 2010 Mar; 45(3):1181-8. PubMed ID: 20053481
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Determination of the kinetic parameters of Escherichia coli leader peptidase activity using a continuous assay: the pH dependence and time-dependent inhibition by beta-lactams are consistent with a novel serine protease mechanism.
    Kuo D; Weidner J; Griffin P; Shah SK; Knight WB
    Biochemistry; 1994 Jul; 33(27):8347-54. PubMed ID: 8031768
    [TBL] [Abstract][Full Text] [Related]  

  • 11. On the absolute configuration in 1,4-dihydrothiazepine covalent complexes derived from inhibition of class A and C beta-lactamases with 6-methylidene penems.
    Mansour TS; Agarwal A; Venkatesan A; Abe T; Mihira A; Takasaki T; Sato K; Ushirogochi H; Yamamura I; Isoda T; Li Z; Yang Y; Kumagai T
    ChemMedChem; 2007 Dec; 2(12):1713-6. PubMed ID: 17868160
    [No Abstract]   [Full Text] [Related]  

  • 12. Total synthesis of the alpha-glucosidase inhibitors schulzeine A, B, and C and a structural revision of schulzeine A.
    Bowen EG; Wardrop DJ
    J Am Chem Soc; 2009 May; 131(17):6062-3. PubMed ID: 19361223
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Asp 280 residue is important in the activity of the Escherichia coli leader peptidase.
    Sung M; Park K
    Exp Mol Med; 1999 Jun; 31(2):64-9. PubMed ID: 10410304
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dibasic inhibitors of human mast cell tryptase. Part 3: identification of a series of potent and selective inhibitors containing the benzamidine functionality.
    Dener JM; Rice KD; Newcomb WS; Wang VR; Young WB; Gangloff AR; Kuo EY; Cregar L; Putnam D; Wong M
    Bioorg Med Chem Lett; 2001 Jul; 11(13):1629-33. PubMed ID: 11425524
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Spongolactams, farnesyl transferase inhibitors from a marine sponge: isolation through an LC/MS-guided assay, structures, and semisyntheses.
    Mori D; Kimura Y; Kitamura S; Sakagami Y; Yoshioka Y; Shintani T; Okamoto T; Ojika M
    J Org Chem; 2007 Sep; 72(19):7190-8. PubMed ID: 17713950
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Halogenated D-xylono-δ-lactams: synthesis and enzyme inhibition study.
    Bhuma N; Vangala M; Nair RJ; Sabharwal SG; Dhavale DD
    Carbohydr Res; 2015 Jan; 402():215-24. PubMed ID: 25498022
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of purified Escherichia coli leader peptidase by the leader (signal) peptide of bacteriophage M13 procoat.
    Wickner W; Moore K; Dibb N; Geissert D; Rice M
    J Bacteriol; 1987 Aug; 169(8):3821-2. PubMed ID: 3301818
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protamine: a unique and potent inhibitor of oligopeptidase B.
    Tsuji A; Yoshimoto T; Yuasa K; Matsuda Y
    J Pept Sci; 2006 Jan; 12(1):65-71. PubMed ID: 15948139
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of penem inhibitors of bacterial signal peptidase.
    Harris DA; Powers ME; Romesberg FE
    Bioorg Med Chem Lett; 2009 Jul; 19(14):3787-90. PubMed ID: 19427205
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pyrrolidine-5,5-trans-lactams. 2. The use of X-ray crystal structure data in the optimization of P3 and P4 substituents.
    Andrews DM; Chaignot H; Coomber BA; Good AC; Hind SL; Johnson MR; Jones PS; Mills G; Robinson JE; Skarzynski T; Slater MJ; Somers DO
    Org Lett; 2002 Dec; 4(25):4479-82. PubMed ID: 12465917
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.