These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

92 related articles for article (PubMed ID: 8935164)

  • 1. Synthesis and biological evaluation of 3-(prop-2-enyl)- and 3-(prop-2-ynyl)pyrrolidine-2,5-dione derivatives as potential aromatase inhibitors.
    Barrell KJ; Woo WL; Ahmadi M; Smith HJ; Nicholls PJ
    J Pharm Pharmacol; 1996 Feb; 48(2):154-9. PubMed ID: 8935164
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Some 1-, and 3-substituted 3-(4'-aminophenyl)pyrrolidine-2,5-diones as selective inhibitors of aromatase.
    Whomsley R; Smith HJ; Nicholls PJ; Nazareth W; Ahmadi M
    J Enzyme Inhib; 1992; 6(4):317-30. PubMed ID: 1284968
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biochemical evaluation of analogues of aminoglutethimide based on phenylpyrrolidine-2,5-dione.
    Daly MJ; Jones GW; Nicholls PJ; Smith HJ; Rowlands MG; Bunnett MA
    J Med Chem; 1986 Apr; 29(4):520-3. PubMed ID: 3754286
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analogues of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activity.
    Rowlands MG; Bunnett MA; Foster AB; Jarman M; Stanek J; Schweizer E
    J Med Chem; 1988 May; 31(5):971-6. PubMed ID: 3361583
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Analogues of 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione as selective inhibitors of aromatase: derivatives with variable 1-alkyl and 3-alkyl substituents.
    Leung CS; Rowlands MG; Jarman M; Foster AB; Griggs LJ; Wilman DE
    J Med Chem; 1987 Sep; 30(9):1550-4. PubMed ID: 3625703
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of novel pyrrolidine-2,5-dione inhibitors as potential anti-tumour agents.
    Ahmed S; Smith JH; Nicholls PJ; Whomsley R; Cariuk P
    Drug Des Discov; 1995 Apr; 12(4):275-87. PubMed ID: 9040988
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmacology of aminoglutethimide: structure/activity relationships and receptor interactions.
    Nicholls PJ; Daly MJ; Smith HJ
    Breast Cancer Res Treat; 1986; 7 Suppl():S55-67. PubMed ID: 3755630
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Analogues of aminoglutethimide: selective inhibition of cholesterol side-chain cleavage.
    Foster AB; Jarman M; Leung CS; Rowlands MG; Taylor GN
    J Med Chem; 1983 Jan; 26(1):50-4. PubMed ID: 6827528
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and aromatase inhibiting activity of aminoglutethimide analogs.
    Aboul-Enein HY
    Drug Des Deliv; 1988 Feb; 2(3):221-6. PubMed ID: 3255316
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and aromatase inhibitory activity of novel 1-(4-aminophenyl)-3-azabicyclo[3.1.0]hexane- and -[3.1.1]heptane-2,4- diones.
    Stanek J; Alder A; Bellus D; Bhatnagar AS; Häusler A; Schieweck K
    J Med Chem; 1991 Apr; 34(4):1329-34. PubMed ID: 2016706
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analogues of aminoglutethimide: selective inhibition of aromatase.
    Foster AB; Jarman M; Leung CS; Rowlands MG; Taylor GN; Plevey RG; Sampson P
    J Med Chem; 1985 Feb; 28(2):200-4. PubMed ID: 3968684
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Inhibitors of aromatase. Synthesis and pharmacologic action of potential mammary tumor-inhibiting 4-alkyl-3-(4-aminophenyl)-3-ethylpiperidine-2,6-diones].
    Batzl C; Hartmann RW
    Arch Pharm (Weinheim); 1987 Jan; 320(1):51-8. PubMed ID: 3566486
    [No Abstract]   [Full Text] [Related]  

  • 13. Crystallographic and molecular modeling studies on 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione and its butyl analogue, inhibitors of mammalian aromatase. Comparison with natural substrates: prediction of enantioselectivity for N-alkyl derivatives.
    Laughton CA; McKenna R; Neidle S; Jarman M; McCague R; Rowlands MG
    J Med Chem; 1990 Sep; 33(9):2673-9. PubMed ID: 2391706
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular modelling study of pyrrolidine-2,5-dione based aromatase inhibitors and other known inhibitors.
    Ahmed S
    Drug Des Discov; 1996 Mar; 14(1):77-89. PubMed ID: 8854046
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 6 beta-Propynyl-substituted steroids: mechanism-based enzyme-activated irreversible inhibitors of aromatase.
    Akkani A; Paterlini G; Gleason WB; Ojala WH; Abul-Hajj YJ
    J Med Chem; 1997 Sep; 40(20):3263-70. PubMed ID: 9379446
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and aromatase inhibition of 3-cycloalkyl-substituted 3-(4-aminophenyl)piperidine-2,6-diones.
    Hartmann RW; Batzl C; Pongratz TM; Mannschreck A
    J Med Chem; 1992 Jun; 35(12):2210-4. PubMed ID: 1613747
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biochemical evaluation of novel inhibitors of aromatase (AR) using an enhanced representation of the active site of AR derived from the consideration of the reaction mechanism.
    Ahmed S; Amanuel Y
    Biochem Biophys Res Commun; 2000 Jan; 267(1):356-61. PubMed ID: 10623624
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interactions of thiol-containing androgens with human placental aromatase.
    Bednarski PJ; Nelson SD
    J Med Chem; 1989 Jan; 32(1):203-13. PubMed ID: 2909733
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 1-Alkyl analogues of aminoglutethimide. Comparative inhibition of cholesterol side chain cleavage and aromatase and metabolism of the 1-propyl derivative, a highly selective inhibitor of aromatase.
    Seago A; Baker MH; Houghton J; Jarman M; Leung CS; Rowlands MG
    Biochem Pharmacol; 1988 Jun; 37(11):2167-72. PubMed ID: 3377817
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Racemisation of drug enantiomers by benzylic proton abstraction at physiological pH.
    Pepper C; Smith HJ; Barrell KJ; Nicholls PJ; Hewlins MJ
    Chirality; 1994; 6(5):400-4. PubMed ID: 8068499
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.