These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 8935714)

  • 1. Tacrolimus (FK 506) biotransformation in primary rat hepatocytes depends on extracellular matrix geometry.
    Bader A; Knop E; Böker KH; Crome O; Frühauf N; Gonschior AK; Christians U; Esselmann H; Pichlmayr R; Sewing KF
    Naunyn Schmiedebergs Arch Pharmacol; 1996 Mar; 353(4):461-73. PubMed ID: 8935714
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Primary porcine enterocyte and hepatocyte cultures to study drug oxidation reactions.
    Bader A; Hansen T; Kirchner G; Allmeling C; Haverich A; Borlak JT
    Br J Pharmacol; 2000 Jan; 129(2):331-42. PubMed ID: 10694240
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of cytochrome P450 3A in the metabolism of mefloquine in human and animal hepatocytes.
    Fontaine F; de Sousa G; Burcham PC; Duchêne P; Rahmani R
    Life Sci; 2000 Apr; 66(22):2193-212. PubMed ID: 10834303
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat.
    Sattler M; Guengerich FP; Yun CH; Christians U; Sewing KF
    Drug Metab Dispos; 1992; 20(5):753-61. PubMed ID: 1385058
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolism and transport of the macrolide immunosuppressant sirolimus in the small intestine.
    Lampen A; Zhang Y; Hackbarth I; Benet LZ; Sewing KF; Christians U
    J Pharmacol Exp Ther; 1998 Jun; 285(3):1104-12. PubMed ID: 9618413
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Use of human organ slices to evaluate the biotransformation and drug-induced side-effects of pharmaceuticals.
    Vickers AE
    Cell Biol Toxicol; 1994 Dec; 10(5-6):407-14. PubMed ID: 7697504
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FK506 (Tacrolimus) decreases the cytotoxicity of cyclosporin A in rat hepatocytes in primary culture: implication of CYP3A induction.
    Ellouk-Achard S; Martin C; Duc HT; Dutertre-Catella H; Thevenin M; Warnet JM; Claude JR
    Arch Toxicol; 1998 Apr; 72(5):257-63. PubMed ID: 9630010
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Isolation from pig liver microsomes, identification by electrospray tandem mass spectrometry and in vitro immunosuppressive activity of a rapamycin tris-epoxide metabolite.
    Lhoëst G; Zey T; Verbeeck RK; Wallemacq P; Maton N; De Houx JP; Latinne D
    J Mass Spectrom; 1999 Jan; 34(1):28-32. PubMed ID: 10028689
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The effect of immunosuppressive agents (FK-506, rapamycin) on renal P450 systems in rat models.
    Yoshimura R; Yoshimura N; Ohyama A; Ohmachi T; Yamamoto K; Kishimoto T; Wada S
    J Pharm Pharmacol; 1999 Aug; 51(8):941-8. PubMed ID: 10504034
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolism of tacrolimus (FK 506) in rat liver microsomes. Effect of rifampin and dexamethasone.
    Prasad ; Tata NV; Subbotina N; Burckart G; Swaminathan A; Gusev AI; Hercules DM; Venkataramanan R
    Res Commun Mol Pathol Pharmacol; 1997 Apr; 96(1):107-10. PubMed ID: 9178371
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Viability and differentiation of human hepatocytes immunoprotected by macroencapsulation and transplanted in rats].
    Nicoluzzi JE; Barbu V; Baudrimont M; Lakehal F; Becquemont L; Chafaï N; Delelo R; Sarkis R; Honiger J; Housset C; Balladur P
    Gastroenterol Clin Biol; 2000 Mar; 24(3):342-8. PubMed ID: 10804344
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Influence of extracellular matrix overlay and medium formulation on the induction of cytochrome P-450 2B enzymes in primary cultures of rat hepatocytes.
    LeCluyse E; Bullock P; Madan A; Carroll K; Parkinson A
    Drug Metab Dispos; 1999 Aug; 27(8):909-15. PubMed ID: 10421618
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The multidrug resistance modulator valspodar (PSC 833) is metabolized by human cytochrome P450 3A. Implications for drug-drug interactions and pharmacological activity of the main metabolite.
    Fischer V; Rodríguez-Gascón A; Heitz F; Tynes R; Hauck C; Cohen D; Vickers AE
    Drug Metab Dispos; 1998 Aug; 26(8):802-11. PubMed ID: 9698296
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Amiodarone N-deethylation in human liver microsomes: involvement of cytochrome P450 3A enzymes (first report).
    Trivier JM; Libersa C; Belloc C; Lhermitte M
    Life Sci; 1993; 52(10):PL91-6. PubMed ID: 8445979
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro biotransformation of a novel antimalarial cysteine protease inhibitor in human liver microsomes.
    Zhang Y; Guo X; Lin ET; Benet LZ
    Pharmacology; 1999 Mar; 58(3):147-59. PubMed ID: 9925971
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Implication of CYP 3A in the toxicity of cyclosporin G (CsG), cyclosporin A (CsA) and FK506 on rat hepatocytes in primary culture.
    Ellouk-Achard S; Martin C; Pham-Huy C; Duc HT; Thevenin M; Dutertre-Catella H; Warnet JM; Claude JR
    Arch Toxicol; 1997; 71(7):437-42. PubMed ID: 9209689
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Clinically significant drug interactions with new immunosuppressive agents.
    Mignat C
    Drug Saf; 1997 Apr; 16(4):267-78. PubMed ID: 9113494
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Posttranscriptional elevation of cytochrome P450 3A expression.
    Zangar RC; Hernandez M; Novak RF
    Biochem Biophys Res Commun; 1997 Feb; 231(1):203-5. PubMed ID: 9070249
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Toxicity of the heterocyclic amine batracylin: investigation of rodent N-acetyltransferase activity and potential contribution of cytochrome P450 3A.
    Stevens GJ; Burkey JL; McQueen CA
    Cell Biol Toxicol; 2000; 16(1):31-9. PubMed ID: 10890504
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability.
    Lampen A; Christians U; Guengerich FP; Watkins PB; Kolars JC; Bader A; Gonschior AK; Dralle H; Hackbarth I; Sewing KF
    Drug Metab Dispos; 1995 Dec; 23(12):1315-24. PubMed ID: 8689938
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.