154 related articles for article (PubMed ID: 8937460)
1. Dietary folate and folylpolyglutamate synthetase activity in normal and neoplastic murine tissues and human tumor xenografts.
Gates SB; Worzalla JF; Shih C; Grindey GB; Mendelsohn LG
Biochem Pharmacol; 1996 Nov; 52(9):1477-9. PubMed ID: 8937460
[TBL] [Abstract][Full Text] [Related]
2. The role of dietary folate in modulation of folate receptor expression, folylpolyglutamate synthetase activity and the efficacy and toxicity of lometrexol.
Mendelsohn LG; Gates SB; Habeck LL; Shackelford KA; Worzalla J; Shih C; Grindey GB
Adv Enzyme Regul; 1996; 36():365-81. PubMed ID: 8869756
[TBL] [Abstract][Full Text] [Related]
3. Whole-body disposition and polyglutamate distribution of the GAR formyltransferase inhibitors LY309887 and lometrexol in mice: effect of low-folate diet.
Habeck LL; Chay SH; Pohland RC; Worzalla JF; Shih C; Mendelsohn LG
Cancer Chemother Pharmacol; 1998; 41(3):201-9. PubMed ID: 9443636
[TBL] [Abstract][Full Text] [Related]
4. Folylpoly-γ-glutamate synthetase: A key determinant of folate homeostasis and antifolate resistance in cancer.
Raz S; Stark M; Assaraf YG
Drug Resist Updat; 2016 Sep; 28():43-64. PubMed ID: 27620954
[TBL] [Abstract][Full Text] [Related]
5. Structural requirements for the activity of antifolates as substrates for mammalian folylpolyglutamate synthetase.
Moran RG; Colman PD; Rosowsky A
NCI Monogr; 1987; (5):133-8. PubMed ID: 2448651
[TBL] [Abstract][Full Text] [Related]
6. Relevance of tumoral folylpolyglutamate synthetase and reduced folates for optimal 5-fluorouracil efficacy: experimental data.
Chéradame S; Etienne MC; Chazal M; Guillot T; Fischel JL; Formento P; Milano G
Eur J Cancer; 1997 May; 33(6):950-9. PubMed ID: 9291820
[TBL] [Abstract][Full Text] [Related]
7. Screening of colon tumor cells and tissues for folylpolyglutamate synthetase activity.
van der Wilt CL; Cloos J; de Jong M; Pinedo HM; Peters GJ
Oncol Res; 1995; 7(6):317-21. PubMed ID: 8527866
[TBL] [Abstract][Full Text] [Related]
8. Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis.
Mendelsohn LG; Shih C; Chen VJ; Habeck LL; Gates SB; Shackelford KA
Semin Oncol; 1999 Apr; 26(2 Suppl 6):42-7. PubMed ID: 10598554
[TBL] [Abstract][Full Text] [Related]
9. Augmentation of the therapeutic activity of lometrexol -(6-R)5,10-dideazatetrahydrofolate- by oral folic acid.
Alati T; Worzalla JF; Shih C; Bewley JR; Lewis S; Moran RG; Grindey GB
Cancer Res; 1996 May; 56(10):2331-5. PubMed ID: 8625328
[TBL] [Abstract][Full Text] [Related]
10. Loss of folylpoly-gamma-glutamate synthetase activity is a dominant mechanism of resistance to polyglutamylation-dependent novel antifolates in multiple human leukemia sublines.
Liani E; Rothem L; Bunni MA; Smith CA; Jansen G; Assaraf YG
Int J Cancer; 2003 Feb; 103(5):587-99. PubMed ID: 12494465
[TBL] [Abstract][Full Text] [Related]
11. Biochemistry and pharmacology of glycinamide ribonucleotide formyltransferase inhibitors: LY309887 and lometrexol.
Mendelsohn LG; Shih C; Schultz RM; Worzalla JF
Invest New Drugs; 1996; 14(3):287-94. PubMed ID: 8958184
[TBL] [Abstract][Full Text] [Related]
12. In vivo evidence for a significant role of folylpolyglutamate synthase in combined chemotherapy with oral fluoropyrimidine, UFT or S-1, and leucovorin.
Tsukioka S; Sakamoto E; Tsujimoto H; Nakagawa F; Saito H; Uchida J; Kiniwa M; Fukushima M
Oncol Rep; 2011 May; 25(5):1407-12. PubMed ID: 21380490
[TBL] [Abstract][Full Text] [Related]
13. Regulation of folate and one-carbon metabolism in mammalian cells. I. Folate metabolism in Chinese hamster ovary cells expressing Escherichia coli or human folylpoly-gamma-glutamate synthetase activity.
Osborne CB; Lowe KE; Shane B
J Biol Chem; 1993 Oct; 268(29):21657-64. PubMed ID: 8408018
[TBL] [Abstract][Full Text] [Related]
14. Marked suppression of the activity of some, but not all, antifolate compounds by augmentation of folate cofactor pools within tumor cells.
Zhao R; Gao F; Goldman ID
Biochem Pharmacol; 2001 Apr; 61(7):857-65. PubMed ID: 11274972
[TBL] [Abstract][Full Text] [Related]
15. Human liver folylpolyglutamate synthetase: biochemical characterization and interactions with folates and folate antagonists.
Clarke L; Waxman DJ
Arch Biochem Biophys; 1987 Aug; 256(2):585-96. PubMed ID: 3619447
[TBL] [Abstract][Full Text] [Related]
16. In vitro uptake, anabolism, and cellular retention of 1843U89 and other benzoquinazoline inhibitors of thymidylate synthase.
Hanlon MH; Ferone R
Cancer Res; 1996 Jul; 56(14):3301-6. PubMed ID: 8764125
[TBL] [Abstract][Full Text] [Related]
17. Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.
Westerhof GR; Schornagel JH; Kathmann I; Jackman AL; Rosowsky A; Forsch RA; Hynes JB; Boyle FT; Peters GJ; Pinedo HM
Mol Pharmacol; 1995 Sep; 48(3):459-71. PubMed ID: 7565626
[TBL] [Abstract][Full Text] [Related]
18. Folylpoly-gamma-glutamate synthetase: generation of isozymes and the role in one carbon metabolism and antifolate cytotoxicity.
Qi H; Atkinson I; Xiao S; Choi YJ; Tobimatsu T; Shane B
Adv Enzyme Regul; 1999; 39():263-73. PubMed ID: 10470377
[TBL] [Abstract][Full Text] [Related]
19. Effect of polyglutamylation of methotrexate on its accumulation and the development of resistance in the protozoan parasite Leishmania.
El-Fadili A; Richard D; Kündig C; Ouellette M
Biochem Pharmacol; 2003 Sep; 66(6):999-1008. PubMed ID: 12963486
[TBL] [Abstract][Full Text] [Related]
20. Humanizing mouse folate metabolism: conversion of the dual-promoter mouse folylpolyglutamate synthetase gene to the human single-promoter structure.
Yang C; Xie LY; Windle JJ; Taylor SM; Moran RG
FASEB J; 2014 May; 28(5):1998-2008. PubMed ID: 24532667
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]