These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 8946477)

  • 41. Identification of human cytochrome P450 isoforms involved in the metabolism of S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid.
    Taguchi K; Konishi T; Nishikawa H; Kitamura S
    Xenobiotica; 1999 Sep; 29(9):899-907. PubMed ID: 10548450
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Role of CYP2D6 in the N-hydroxylation of procainamide.
    Lessard E; Fortin A; Bélanger PM; Beaune P; Hamelin BA; Turgeon J
    Pharmacogenetics; 1997 Oct; 7(5):381-90. PubMed ID: 9352574
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Identification of CYP3A4 as the principal enzyme catalyzing mifepristone (RU 486) oxidation in human liver microsomes.
    Jang GR; Wrighton SA; Benet LZ
    Biochem Pharmacol; 1996 Sep; 52(5):753-61. PubMed ID: 8765473
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
    Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
    [TBL] [Abstract][Full Text] [Related]  

  • 45. In vitro metabolism of the calmodulin antagonist DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) by human liver microsomes: involvement of cytochromes p450 in atypical kinetics and potential drug interactions.
    Tachibana S; Fujimaki Y; Yokoyama H; Okazaki O; Sudo K
    Drug Metab Dispos; 2005 Nov; 33(11):1628-36. PubMed ID: 16049129
    [TBL] [Abstract][Full Text] [Related]  

  • 46. CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver.
    Dehal SS; Kupfer D
    Cancer Res; 1997 Aug; 57(16):3402-6. PubMed ID: 9270005
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Regioselective hydroxylation of an antiarrhythmic drug, propafenone, mediated by rat liver cytochrome P450 2D2 differs from that catalyzed by human P450 2D6.
    Uehara S; Murayama N; Yamazaki H; Suemizu H
    Xenobiotica; 2019 Nov; 49(11):1323-1331. PubMed ID: 30596462
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Kinetic characteristics of norcocaine N-hydroxylation in mouse and human liver microsomes: involvement of CYP enzymes.
    Pellinen P; Kulmala L; Konttila J; Auriola S; Pasanen M; Juvonen R
    Arch Toxicol; 2000 Nov; 74(9):511-20. PubMed ID: 11131030
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Identification of cytochrome P450 isozymes involved in metabolism of the alpha1-adrenoceptor blocker tamsulosin in human liver microsomes.
    Kamimura H; Oishi S; Matsushima H; Watanabe T; Higuchi S; Hall M; Wood SG; Chasseaud LF
    Xenobiotica; 1998 Oct; 28(10):909-22. PubMed ID: 9849639
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Inhibitory effects of nicardipine to cytochrome P450 (CYP) in human liver microsomes.
    Nakamura K; Ariyoshi N; Iwatsubo T; Fukunaga Y; Higuchi S; Itoh K; Shimada N; Nagashima K; Yokoi T; Yamamoto K; Horiuchi R; Kamataki T
    Biol Pharm Bull; 2005 May; 28(5):882-5. PubMed ID: 15863898
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Metabolism of dexfenfluramine in human liver microsomes and by recombinant enzymes: role of CYP2D6 and 1A2.
    Haritos VS; Ching MS; Ghabrial H; Gross AS; Taavitsainen P; Pelkonen O; Battaglia SE; Smallwood RA; Ahokas JT
    Pharmacogenetics; 1998 Oct; 8(5):423-32. PubMed ID: 9825834
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6.
    Song M; Hong M; Lee MY; Jee JG; Lee YM; Bae JS; Jeong TC; Lee S
    Food Chem Toxicol; 2013 Sep; 59():549-53. PubMed ID: 23835282
    [TBL] [Abstract][Full Text] [Related]  

  • 53. The metabolism of aprindine in relation to the sparteine/debrisoquine polymorphism.
    Ebner T; Eichelbaum M
    Br J Clin Pharmacol; 1993 Apr; 35(4):426-30. PubMed ID: 8485023
    [TBL] [Abstract][Full Text] [Related]  

  • 54. The interactions of a selective protein kinase C beta inhibitor with the human cytochromes P450.
    Ring BJ; Gillespie JS; Binkley SN; Campanale KM; Wrighton SA
    Drug Metab Dispos; 2002 Sep; 30(9):957-61. PubMed ID: 12167559
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Cytochrome P450 3A-dependent metabolism of a potent and selective gamma-aminobutyric acid Aalpha2/3 receptor agonist in vitro: involvement of cytochrome P450 3A5 displaying biphasic kinetics.
    Ma B; Polsky-Fisher SL; Vickers S; Cui D; Rodrigues AD
    Drug Metab Dispos; 2007 Aug; 35(8):1301-7. PubMed ID: 17460031
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Stereoselective N-demethylation of chlorpheniramine by rat-liver microsomes and the involvement of cytochrome P450 isozymes.
    Nomura A; Sakurai E; Hikichi N
    J Pharm Pharmacol; 1997 Mar; 49(3):257-62. PubMed ID: 9231341
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Identification of cytochrome P450 enzymes involved in the metabolism of zotepine, an antipsychotic drug, in human liver microsomes.
    Shiraga T; Kaneko H; Iwasaki K; Tozuka Z; Suzuki A; Hata T
    Xenobiotica; 1999 Mar; 29(3):217-29. PubMed ID: 10219963
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Inhibitory effects of antiparasitic drugs on cytochrome P450 2D6.
    Masimirembwa CM; Hasler JA; Johansson I
    Eur J Clin Pharmacol; 1995; 48(1):35-8. PubMed ID: 7621845
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Inhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans.
    Mössner LD; Schmitz A; Theurillat R; Thormann W; Mevissen M
    Am J Vet Res; 2011 Nov; 72(11):1505-13. PubMed ID: 22023129
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.
    Lalovic B; Phillips B; Risler LL; Howald W; Shen DD
    Drug Metab Dispos; 2004 Apr; 32(4):447-54. PubMed ID: 15039299
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.