177 related articles for article (PubMed ID: 8947461)
1. Proinsulin processing in the rat insulinoma cell line INS after overexpression of the endoproteases PC2 or PC3 by recombinant adenovirus.
Irminger JC; Meyer K; Halban P
Biochem J; 1996 Nov; 320 ( Pt 1)(Pt 1):11-5. PubMed ID: 8947461
[TBL] [Abstract][Full Text] [Related]
2. Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3.
Smeekens SP; Montag AG; Thomas G; Albiges-Rizo C; Carroll R; Benig M; Phillips LA; Martin S; Ohagi S; Gardner P
Proc Natl Acad Sci U S A; 1992 Sep; 89(18):8822-6. PubMed ID: 1528899
[TBL] [Abstract][Full Text] [Related]
3. Proinsulin conversion in GH3 cells after coexpression of human proinsulin with the endoproteases PC2 and/or PC3.
Kaufmann JE; Irminger JC; Mungall J; Halban PA
Diabetes; 1997 Jun; 46(6):978-82. PubMed ID: 9166668
[TBL] [Abstract][Full Text] [Related]
4. Processing of synthetic pro-islet amyloid polypeptide (proIAPP) 'amylin' by recombinant prohormone convertase enzymes, PC2 and PC3, in vitro.
Higham CE; Hull RL; Lawrie L; Shennan KI; Morris JF; Birch NP; Docherty K; Clark A
Eur J Biochem; 2000 Aug; 267(16):4998-5004. PubMed ID: 10931181
[TBL] [Abstract][Full Text] [Related]
5. Long-term elevation of free fatty acids leads to delayed processing of proinsulin and prohormone convertases 2 and 3 in the pancreatic beta-cell line MIN6.
Furukawa H; Carroll RJ; Swift HH; Steiner DF
Diabetes; 1999 Jul; 48(7):1395-401. PubMed ID: 10389844
[TBL] [Abstract][Full Text] [Related]
6. Processing of proinsulin by furin, PC2, and PC3 in (co) transfected COS (monkey kidney) cells.
Vollenweider F; Kaufmann J; Irminger JC; Halban PA
Diabetes; 1995 Sep; 44(9):1075-80. PubMed ID: 7657031
[TBL] [Abstract][Full Text] [Related]
7. Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2.
Furuta M; Carroll R; Martin S; Swift HH; Ravazzola M; Orci L; Steiner DF
J Biol Chem; 1998 Feb; 273(6):3431-7. PubMed ID: 9452465
[TBL] [Abstract][Full Text] [Related]
8. Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells.
Schuppin GT; Rhodes CJ
Biochem J; 1996 Jan; 313 ( Pt 1)(Pt 1):259-68. PubMed ID: 8546693
[TBL] [Abstract][Full Text] [Related]
9. Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line.
Skelly RH; Schuppin GT; Ishihara H; Oka Y; Rhodes CJ
Diabetes; 1996 Jan; 45(1):37-43. PubMed ID: 8522057
[TBL] [Abstract][Full Text] [Related]
10. Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus.
Alarcón C; Leahy JL; Schuppin GT; Rhodes CJ
J Clin Invest; 1995 Mar; 95(3):1032-9. PubMed ID: 7883951
[TBL] [Abstract][Full Text] [Related]
11. Levels of the conversion endoproteases PC1 (PC3) and PC2 distinguish between insulin-producing pancreatic islet beta cells and non-beta cells.
Neerman-Arbez M; Cirulli V; Halban PA
Biochem J; 1994 May; 300 ( Pt 1)(Pt 1):57-61. PubMed ID: 8198551
[TBL] [Abstract][Full Text] [Related]
12. Electron microscopic immunocytochemical evidence for the involvement of the convertases PC1 and PC2 in the processing of proinsulin in pancreatic beta-cells.
Malide D; Seidah NG; Chrétien M; Bendayan M
J Histochem Cytochem; 1995 Jan; 43(1):11-9. PubMed ID: 7822759
[TBL] [Abstract][Full Text] [Related]
13. Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3.
Zhu X; Orci L; Carroll R; Norrbom C; Ravazzola M; Steiner DF
Proc Natl Acad Sci U S A; 2002 Aug; 99(16):10299-304. PubMed ID: 12136131
[TBL] [Abstract][Full Text] [Related]
14. Sequence requirements for proinsulin processing at the B-chain/C-peptide junction.
Kaufmann JE; Irminger JC; Halban PA
Biochem J; 1995 Sep; 310 ( Pt 3)(Pt 3):869-74. PubMed ID: 7575420
[TBL] [Abstract][Full Text] [Related]
15. The biosynthesis of the subtilisin-related proprotein convertase PC3, but no that of the PC2 convertase, is regulated by glucose in parallel to proinsulin biosynthesis in rat pancreatic islets.
Alarcón C; Lincoln B; Rhodes CJ
J Biol Chem; 1993 Feb; 268(6):4276-80. PubMed ID: 8440711
[TBL] [Abstract][Full Text] [Related]
16. Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide.
Rouillé Y; Martin S; Steiner DF
J Biol Chem; 1995 Nov; 270(44):26488-96. PubMed ID: 7592866
[TBL] [Abstract][Full Text] [Related]
17. Role of prohormone convertases in pro-neuropeptide Y processing: coexpression and in vitro kinetic investigations.
Brakch N; Rist B; Beck-Sickinger AG; Goenaga J; Wittek R; Bürger E; Brunner HR; Grouzmann E
Biochemistry; 1997 Dec; 36(51):16309-20. PubMed ID: 9405066
[TBL] [Abstract][Full Text] [Related]
18. Role of the prohormone convertase PC3 in the processing of proglucagon to glucagon-like peptide 1.
Rouillé Y; Kantengwa S; Irminger JC; Halban PA
J Biol Chem; 1997 Dec; 272(52):32810-6. PubMed ID: 9407057
[TBL] [Abstract][Full Text] [Related]
19. Regulation by glucose of the biosynthesis of PC2, PC3 and proinsulin in (ob/ob) mouse islets of Langerhans.
Martin SK; Carroll R; Benig M; Steiner DF
FEBS Lett; 1994 Dec; 356(2-3):279-82. PubMed ID: 7805854
[TBL] [Abstract][Full Text] [Related]
20. Functioning human insulinomas. An immunohistochemical analysis of intracellular insulin processing.
Azzoni C; D'Adda T; Tamburrano G; Coscelli C; Madsen OD; Scopsi L; Bordi C
Virchows Arch; 1998 Dec; 433(6):495-504. PubMed ID: 9870681
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
