BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

494 related articles for article (PubMed ID: 8950270)

  • 1. Guided evolution of enzymes with new substrate specificities.
    el Hawrani AS; Sessions RB; Moreton KM; Holbrook JJ
    J Mol Biol; 1996 Nov; 264(1):97-110. PubMed ID: 8950270
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stringency of substrate specificity of Escherichia coli malate dehydrogenase.
    Boernke WE; Millard CS; Stevens PW; Kakar SN; Stevens FJ; Donnelly MI
    Arch Biochem Biophys; 1995 Sep; 322(1):43-52. PubMed ID: 7574693
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A double mutant of highly purified Geobacillus stearothermophilus lactate dehydrogenase recognises l-mandelic acid as a substrate.
    Binay B; Sessions RB; Karagüler NG
    Enzyme Microb Technol; 2013 May; 52(6-7):393-9. PubMed ID: 23608509
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases.
    Lee BI; Chang C; Cho SJ; Eom SH; Kim KK; Yu YG; Suh SW
    J Mol Biol; 2001 Apr; 307(5):1351-62. PubMed ID: 11292347
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Manipulation of the active site loops of D-hydantoinase, a (beta/alpha)8-barrel protein, for modulation of the substrate specificity.
    Cheon YH; Park HS; Kim JH; Kim Y; Kim HS
    Biochemistry; 2004 Jun; 43(23):7413-20. PubMed ID: 15182184
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evolution of lactate dehydrogenase-A homologs of barracuda fishes (genus Sphyraena) from different thermal environments: differences in kinetic properties and thermal stability are due to amino acid substitutions outside the active site.
    Holland LZ; McFall-Ngai M; Somero GN
    Biochemistry; 1997 Mar; 36(11):3207-15. PubMed ID: 9115998
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Allosteric activation in Bacillus stearothermophilus lactate dehydrogenase investigated by an X-ray crystallographic analysis of a mutant designed to prevent tetramerization of the enzyme.
    Cameron AD; Roper DI; Moreton KM; Muirhead H; Holbrook JJ; Wigley DB
    J Mol Biol; 1994 May; 238(4):615-25. PubMed ID: 8176749
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design of a specific phenyllactate dehydrogenase by peptide loop exchange on the Bacillus stearothermophilus lactate dehydrogenase framework.
    Wilks HM; Moreton KM; Halsall DJ; Hart KW; Sessions RD; Clarke AR; Holbrook JJ
    Biochemistry; 1992 Sep; 31(34):7802-6. PubMed ID: 1324721
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A modified consensus approach to mutagenesis inverts the cofactor specificity of Bacillus stearothermophilus lactate dehydrogenase.
    Flores H; Ellington AD
    Protein Eng Des Sel; 2005 Aug; 18(8):369-77. PubMed ID: 16012175
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutational analysis of the thermostable arginine repressor from Bacillus stearothermophilus: dissecting residues involved in DNA binding properties.
    Karaivanova IM; Weigel P; Takahashi M; Fort C; Versavaud A; Van Duyne G; Charlier D; Hallet JN; Glansdorff N; Sakanyan V
    J Mol Biol; 1999 Aug; 291(4):843-55. PubMed ID: 10452892
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Construction of a stable dimer of Bacillus stearothermophilus lactate dehydrogenase.
    Jackson RM; Gelpi JL; Cortes A; Emery DC; Wilks HM; Moreton KM; Halsall DJ; Sleigh RN; Behan-Martin M; Jones GR
    Biochemistry; 1992 Sep; 31(35):8307-14. PubMed ID: 1525168
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein engineering applications of industrially exploitable enzymes: Geobacillus stearothermophilus LDH and Candida methylica FDH.
    Karagüler NG; Sessions RB; Binay B; Ordu EB; Clarke AR
    Biochem Soc Trans; 2007 Dec; 35(Pt 6):1610-5. PubMed ID: 18031276
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substrate specificity determinants of the methanogen homoaconitase enzyme: structure and function of the small subunit.
    Jeyakanthan J; Drevland RM; Gayathri DR; Velmurugan D; Shinkai A; Kuramitsu S; Yokoyama S; Graham DE
    Biochemistry; 2010 Mar; 49(12):2687-96. PubMed ID: 20170198
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Determinants of substrate specificity in the superfamily of amino acid dehydrogenases.
    Baker PJ; Waugh ML; Wang XG; Stillman TJ; Turnbull AP; Engel PC; Rice DW
    Biochemistry; 1997 Dec; 36(51):16109-15. PubMed ID: 9405044
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Importance of the gamma-carboxyl group of glutamate-462 of the large alpha-subunit for the catalytic function and the stability of the multienzyme complex of fatty acid oxidation from Escherichia coli.
    He XY; Deng H; Yang SY
    Biochemistry; 1997 Jan; 36(1):261-8. PubMed ID: 8993342
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evolutionary convergence in adaptation of proteins to temperature: A4-lactate dehydrogenases of Pacific damselfishes (Chromis spp.).
    Johns GC; Somero GN
    Mol Biol Evol; 2004 Feb; 21(2):314-20. PubMed ID: 14660697
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Site-directed mutagenesis of histidine-90 in Escherichia coli L-threonine dehydrogenase alters its substrate specificity.
    Johnson AR; Dekker EE
    Arch Biochem Biophys; 1998 Mar; 351(1):8-16. PubMed ID: 9500838
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Semi-Rational Design of Geobacillus stearothermophilus L-Lactate Dehydrogenase to Access Various Chiral α-Hydroxy Acids.
    Aslan AS; Birmingham WR; Karagüler NG; Turner NJ; Binay B
    Appl Biochem Biotechnol; 2016 Jun; 179(3):474-84. PubMed ID: 26852025
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Investigation of a catalytic zinc binding site in Escherichia coli L-threonine dehydrogenase by site-directed mutagenesis of cysteine-38.
    Johnson AR; Chen YW; Dekker EE
    Arch Biochem Biophys; 1998 Oct; 358(2):211-21. PubMed ID: 9784233
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The crystal structure of d-glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaeon Methanothermus fervidus in the presence of NADP(+) at 2.1 A resolution.
    Charron C; Talfournier F; Isupov MN; Littlechild JA; Branlant G; Vitoux B; Aubry A
    J Mol Biol; 2000 Mar; 297(2):481-500. PubMed ID: 10715215
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.