These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 8952501)

  • 1. The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase.
    Komives EA; Lougheed JC; Zhang Z; Sugio S; Narayana N; Xuong NH; Petsko GA; Ringe D
    Biochemistry; 1996 Dec; 35(48):15474-84. PubMed ID: 8952501
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of water in the catalytic efficiency of triosephosphate isomerase.
    Zhang Z; Komives EA; Sugio S; Blacklow SC; Narayana N; Xuong NH; Stock AM; Petsko GA; Ringe D
    Biochemistry; 1999 Apr; 38(14):4389-97. PubMed ID: 10194358
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The structural basis for pseudoreversion of the E165D lesion by the secondary S96P mutation in triosephosphate isomerase depends on the positions of active site water molecules.
    Komives EA; Lougheed JC; Liu K; Sugio S; Zhang Z; Petsko GA; Ringe D
    Biochemistry; 1995 Oct; 34(41):13612-21. PubMed ID: 7577950
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NMR studies of the role of hydrogen bonding in the mechanism of triosephosphate isomerase.
    Harris TK; Abeygunawardana C; Mildvan AS
    Biochemistry; 1997 Dec; 36(48):14661-75. PubMed ID: 9398185
    [TBL] [Abstract][Full Text] [Related]  

  • 5. How can a catalytic lesion be offset? The energetics of two pseudorevertant triosephosphate isomerases.
    Blacklow SC; Knowles JR
    Biochemistry; 1990 May; 29(17):4099-108. PubMed ID: 2361134
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Atomic resolution crystallography of a complex of triosephosphate isomerase with a reaction-intermediate analog: new insight in the proton transfer reaction mechanism.
    Alahuhta M; Wierenga RK
    Proteins; 2010 Jun; 78(8):1878-88. PubMed ID: 20235230
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Active site properties of monomeric triosephosphate isomerase (monoTIM) as deduced from mutational and structural studies.
    Schliebs W; Thanki N; Eritja R; Wierenga R
    Protein Sci; 1996 Feb; 5(2):229-39. PubMed ID: 8745400
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric and monomeric TIM.
    Alahuhta M; Casteleijn MG; Neubauer P; Wierenga RK
    Acta Crystallogr D Biol Crystallogr; 2008 Feb; 64(Pt 2):178-88. PubMed ID: 18219118
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution.
    Zhang Z; Sugio S; Komives EA; Liu KD; Knowles JR; Petsko GA; Ringe D
    Biochemistry; 1994 Mar; 33(10):2830-7. PubMed ID: 8130195
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
    Noble ME; Wierenga RK; Lambeir AM; Opperdoes FR; Thunnissen AM; Kalk KH; Groendijk H; Hol WG
    Proteins; 1991; 10(1):50-69. PubMed ID: 2062828
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Proton transfer in the mechanism of triosephosphate isomerase.
    Harris TK; Cole RN; Comer FI; Mildvan AS
    Biochemistry; 1998 Nov; 37(47):16828-38. PubMed ID: 9843453
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Revisiting the mechanism of the triosephosphate isomerase reaction: the role of the fully conserved glutamic acid 97 residue.
    Samanta M; Murthy MR; Balaram H; Balaram P
    Chembiochem; 2011 Aug; 12(12):1886-96. PubMed ID: 21671330
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structures of the "open" and "closed" state of trypanosomal triosephosphate isomerase, as observed in a new crystal form: implications for the reaction mechanism.
    Noble ME; Zeelen JP; Wierenga RK
    Proteins; 1993 Aug; 16(4):311-26. PubMed ID: 8356028
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Solution-state NMR investigations of triosephosphate isomerase active site loop motion: ligand release in relation to active site loop dynamics.
    Rozovsky S; Jogl G; Tong L; McDermott AE
    J Mol Biol; 2001 Jun; 310(1):271-80. PubMed ID: 11419952
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanistic implications of methylglyoxal synthase complexed with phosphoglycolohydroxamic acid as observed by X-ray crystallography and NMR spectroscopy.
    Marks GT; Harris TK; Massiah MA; Mildvan AS; Harrison DH
    Biochemistry; 2001 Jun; 40(23):6805-18. PubMed ID: 11389594
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Electrophilic catalysis in triosephosphate isomerase: the role of histidine-95.
    Komives EA; Chang LC; Lolis E; Tilton RF; Petsko GA; Knowles JR
    Biochemistry; 1991 Mar; 30(12):3011-9. PubMed ID: 2007138
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinetic and structural properties of triosephosphate isomerase from Helicobacter pylori.
    Chu CH; Lai YJ; Huang H; Sun YJ
    Proteins; 2008 Apr; 71(1):396-406. PubMed ID: 17957775
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Computational modeling of the catalytic reaction in triosephosphate isomerase.
    Guallar V; Jacobson M; McDermott A; Friesner RA
    J Mol Biol; 2004 Mar; 337(1):227-39. PubMed ID: 15001364
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure of the triosephosphate isomerase-phosphoglycolohydroxamate complex: an analogue of the intermediate on the reaction pathway.
    Davenport RC; Bash PA; Seaton BA; Karplus M; Petsko GA; Ringe D
    Biochemistry; 1991 Jun; 30(24):5821-6. PubMed ID: 2043623
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-based protein engineering efforts with a monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties.
    Alahuhta M; Salin M; Casteleijn MG; Kemmer C; El-Sayed I; Augustyns K; Neubauer P; Wierenga RK
    Protein Eng Des Sel; 2008 Apr; 21(4):257-66. PubMed ID: 18239072
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.