BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

383 related articles for article (PubMed ID: 8955094)

  • 1. Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways.
    Mège D; Di Bartolo V; Germain V; Tuosto L; Michel F; Acuto O
    J Biol Chem; 1996 Dec; 271(51):32644-52. PubMed ID: 8955094
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.
    Williams BL; Irvin BJ; Sutor SL; Chini CC; Yacyshyn E; Bubeck Wardenburg J; Dalton M; Chan AC; Abraham RT
    EMBO J; 1999 Apr; 18(7):1832-44. PubMed ID: 10202147
    [TBL] [Abstract][Full Text] [Related]  

  • 3. T cell activation stimulates the association of enzymatically active tyrosine-phosphorylated ZAP-70 with the Crk adapter proteins.
    Gelkop S; Isakov N
    J Biol Chem; 1999 Jul; 274(31):21519-27. PubMed ID: 10419455
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk.
    Williams S; Couture C; Gilman J; Jascur T; Deckert M; Altman A; Mustelin T
    Eur J Biochem; 1997 Apr; 245(1):84-90. PubMed ID: 9128727
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tyrosine 474 of ZAP-70 is required for association with the Shc adaptor and for T-cell antigen receptor-dependent gene activation.
    Pacini S; Ulivieri C; Di Somma MM; Isacchi A; Lanfrancone L; Pelicci PG; Telford JL; Baldari CT
    J Biol Chem; 1998 Aug; 273(32):20487-93. PubMed ID: 9685404
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The oncogenic 70Z Cbl mutation blocks the phosphotyrosine binding domain-dependent negative regulation of ZAP-70 by c-Cbl in Jurkat T cells.
    van Leeuwen JE; Paik PK; Samelson LE
    Mol Cell Biol; 1999 Oct; 19(10):6652-64. PubMed ID: 10490604
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc.
    Walk SF; March ME; Ravichandran KS
    Eur J Immunol; 1998 Aug; 28(8):2265-75. PubMed ID: 9710204
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction.
    Straus DB; Chan AC; Patai B; Weiss A
    J Biol Chem; 1996 Apr; 271(17):9976-81. PubMed ID: 8626636
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A dual participation of ZAP-70 and scr protein tyrosine kinases is required for TCR-induced tyrosine phosphorylation of Sam68 in Jurkat T cells.
    Lang V; Mège D; Semichon M; Gary-Gouy H; Bismuth G
    Eur J Immunol; 1997 Dec; 27(12):3360-7. PubMed ID: 9464824
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rosmarinic acid inhibits Ca2+-dependent pathways of T-cell antigen receptor-mediated signaling by inhibiting the PLC-gamma 1 and Itk activity.
    Kang MA; Yun SY; Won J
    Blood; 2003 May; 101(9):3534-42. PubMed ID: 12511421
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling.
    Qian D; Mollenauer MN; Weiss A
    J Exp Med; 1996 Feb; 183(2):611-20. PubMed ID: 8627172
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation: a potential role for tyrosine phosphatases.
    Guntermann C; Alexander DR
    J Immunol; 2002 May; 168(9):4420-9. PubMed ID: 11970985
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling.
    Denny MF; Kaufman HC; Chan AC; Straus DB
    J Biol Chem; 1999 Feb; 274(8):5146-52. PubMed ID: 9988764
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential T-cell antigen receptor signaling mediated by the Src family kinases Lck and Fyn.
    Denny MF; Patai B; Straus DB
    Mol Cell Biol; 2000 Feb; 20(4):1426-35. PubMed ID: 10648627
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A direct interaction between the adaptor protein Cbl-b and the kinase zap-70 induces a positive signal in T cells.
    Zhang Z; Elly C; Qiu L; Altman A; Liu YC
    Curr Biol; 1999 Feb; 9(4):203-6. PubMed ID: 10074432
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dephosphorylation of ZAP-70 and inhibition of T cell activation by activated SHP1.
    Brockdorff J; Williams S; Couture C; Mustelin T
    Eur J Immunol; 1999 Aug; 29(8):2539-50. PubMed ID: 10458769
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex.
    Thome M; Duplay P; Guttinger M; Acuto O
    J Exp Med; 1995 Jun; 181(6):1997-2006. PubMed ID: 7539035
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phospho-LAT-independent activation of the ras-mitogen-activated protein kinase pathway: a differential recruitment model of TCR partial agonist signaling.
    Chau LA; Madrenas J
    J Immunol; 1999 Aug; 163(4):1853-8. PubMed ID: 10438919
    [TBL] [Abstract][Full Text] [Related]  

  • 19. p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation.
    Raab M; Cai YC; Bunnell SC; Heyeck SD; Berg LJ; Rudd CE
    Proc Natl Acad Sci U S A; 1995 Sep; 92(19):8891-5. PubMed ID: 7568038
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphorylation of the Grb2- and phosphatidylinositol 3-kinase p85-binding p36/38 by Syk in Lck-negative T cells.
    von Willebrand M; Williams S; Tailor P; Mustelin T
    Cell Signal; 1998 Jun; 10(6):407-13. PubMed ID: 9720763
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.