249 related articles for article (PubMed ID: 8955349)
1. Coexpression of a human P450 (CYP3A4) and P450 reductase generates a highly functional monooxygenase system in Escherichia coli.
Blake JA; Pritchard M; Ding S; Smith GC; Burchell B; Wolf CR; Friedberg T
FEBS Lett; 1996 Nov; 397(2-3):210-4. PubMed ID: 8955349
[TBL] [Abstract][Full Text] [Related]
2. Molecular characterization of specifically active recombinant fused enzymes consisting of CYP3A4, NADPH-cytochrome P450 oxidoreductase, and cytochrome b5.
Inui H; Maeda A; Ohkawa H
Biochemistry; 2007 Sep; 46(35):10213-21. PubMed ID: 17691855
[TBL] [Abstract][Full Text] [Related]
3. Coexpression of genetically engineered fused enzyme between yeast NADPH-P450 reductase and human cytochrome P450 3A4 and human cytochrome b5 in yeast.
Hayashi K; Sakaki T; Kominami S; Inouye K; Yabusaki Y
Arch Biochem Biophys; 2000 Sep; 381(1):164-70. PubMed ID: 11019832
[TBL] [Abstract][Full Text] [Related]
4. Enhancement of cytochrome P-450 3A4 catalytic activities by cytochrome b(5) in bacterial membranes.
Yamazaki H; Nakajima M; Nakamura M; Asahi S; Shimada N; Gillam EM; Guengerich FP; Shimada T; Yokoi T
Drug Metab Dispos; 1999 Sep; 27(9):999-1004. PubMed ID: 10460798
[TBL] [Abstract][Full Text] [Related]
5. Expression of cytochrome P450 3A7 in Escherichia coli: effects of 5' modification and catalytic characterization of recombinant enzyme expressed in bicistronic format with NADPH-cytochrome P450 reductase.
Gillam EM; Wunsch RM; Ueng YF; Shimada T; Reilly PE; Kamataki T; Guengerich FP
Arch Biochem Biophys; 1997 Oct; 346(1):81-90. PubMed ID: 9328287
[TBL] [Abstract][Full Text] [Related]
6. Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes.
Yamazaki H; Nakano M; Imai Y; Ueng YF; Guengerich FP; Shimada T
Arch Biochem Biophys; 1996 Jan; 325(2):174-82. PubMed ID: 8561495
[TBL] [Abstract][Full Text] [Related]
7. High rates of substrate hydroxylation by human cytochrome P450 3A4 in reconstituted membranous vesicles: influence of membrane charge.
Ingelman-Sundberg M; Hagbjörk AL; Ueng YF; Yamazaki H; Guengerich FP
Biochem Biophys Res Commun; 1996 Apr; 221(2):318-22. PubMed ID: 8619853
[TBL] [Abstract][Full Text] [Related]
8. High levels of recombinant CYP3A4 expression in Chinese hamster ovary cells are modulated by coexpressed human P450 reductase and hemin supplementation.
Ding S; Yao D; Burchell B; Wolf CR; Friedberg T
Arch Biochem Biophys; 1997 Dec; 348(2):403-10. PubMed ID: 9434754
[TBL] [Abstract][Full Text] [Related]
9. Effects of human cytochrome b5 on CYP3A4 activity and stability in vivo.
Voice MW; Zhang Y; Wolf CR; Burchell B; Friedberg T
Arch Biochem Biophys; 1999 Jun; 366(1):116-24. PubMed ID: 10334871
[TBL] [Abstract][Full Text] [Related]
10. Roles of divalent metal ions in oxidations catalyzed by recombinant cytochrome P450 3A4 and replacement of NADPH--cytochrome P450 reductase with other flavoproteins, ferredoxin, and oxygen surrogates.
Yamazaki H; Ueng YF; Shimada T; Guengerich FP
Biochemistry; 1995 Jul; 34(26):8380-9. PubMed ID: 7599128
[TBL] [Abstract][Full Text] [Related]
11. Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.
Yamazaki H; Gillam EM; Dong MS; Johnson WW; Guengerich FP; Shimada T
Arch Biochem Biophys; 1997 Jun; 342(2):329-37. PubMed ID: 9186495
[TBL] [Abstract][Full Text] [Related]
12. CYP3A4 expressed by insect cells infected with a recombinant baculovirus containing both CYP3A4 and human NADPH-cytochrome P450 reductase is catalytically similar to human liver microsomal CYP3A4.
Lee CA; Kadwell SH; Kost TA; Serabjit-Singh CJ
Arch Biochem Biophys; 1995 May; 319(1):157-67. PubMed ID: 7771780
[TBL] [Abstract][Full Text] [Related]
13. Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.
Yamazaki H; Johnson WW; Ueng YF; Shimada T; Guengerich FP
J Biol Chem; 1996 Nov; 271(44):27438-44. PubMed ID: 8910324
[TBL] [Abstract][Full Text] [Related]
14. High catalytic activity of human cytochrome P450 co-expressed with human NADPH-cytochrome P450 reductase in Escherichia coli.
Iwata H; Fujita K; Kushida H; Suzuki A; Konno Y; Nakamura K; Fujino A; Kamataki T
Biochem Pharmacol; 1998 Apr; 55(8):1315-25. PubMed ID: 9719488
[TBL] [Abstract][Full Text] [Related]
15. Influence of glutathione on the catalytic activity of reconstituted cytochrome P450 3A4.
Kim BR; Kim DH
Biochem Biophys Res Commun; 1998 Jan; 242(1):209-12. PubMed ID: 9439637
[TBL] [Abstract][Full Text] [Related]
16. Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme.
Gillam EM; Baba T; Kim BR; Ohmori S; Guengerich FP
Arch Biochem Biophys; 1993 Aug; 305(1):123-31. PubMed ID: 8342945
[TBL] [Abstract][Full Text] [Related]
17. Reconstitution premixes for assays using purified recombinant human cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b5.
Shaw PM; Hosea NA; Thompson DV; Lenius JM; Guengerich FP
Arch Biochem Biophys; 1997 Dec; 348(1):107-15. PubMed ID: 9390180
[TBL] [Abstract][Full Text] [Related]
18. Stable expression of human cytochrome P450 3A4 in conjunction with human NADPH-cytochrome P450 oxidoreductase in V79 Chinese hamster cells.
Schneider A; Schmalix WA; Siruguri V; de Groene EM; Horbach GJ; Kleingeist B; Lang D; Böcker R; Belloc C; Beaune P; Greim H; Doehmer J
Arch Biochem Biophys; 1996 Aug; 332(2):295-304. PubMed ID: 8806738
[TBL] [Abstract][Full Text] [Related]
19. Kinetics of testosterone 6beta-hydroxylation in the reconstituted system with similar ratios of purified CYP3A4, NADPH-cytochrome p450 oxidoreductase and cytochrome B5 to human liver microsomes.
Taguchi M; Imaoka S; Yoshii K; Kobayashi K; Hosokawa M; Shimada N; Funae Y; Chiba K
Res Commun Mol Pathol Pharmacol; 2001 Jul; 109(1-2):53-63. PubMed ID: 11458985
[TBL] [Abstract][Full Text] [Related]
20. Studies on the interactions between drugs and estrogen: analytical method for prediction system of gynecomastia induced by drugs on the inhibitory metabolism of estradiol using Escherichia coli coexpressing human CYP3A4 with human NADPH-cytochrome P450 reductase.
Satoh T; Fujita KI; Munakata H; Itoh S; Nakamura K; Kamataki T; Itoh S; Yoshizawa I
Anal Biochem; 2000 Nov; 286(2):179-86. PubMed ID: 11067738
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
