155 related articles for article (PubMed ID: 8958187)
21. Role of folylpolygutamate synthetase (FPGS) in antifolate chemotherapy; a biochemical and clinical update.
Synold TW; Willits EM; Barredo JC
Leuk Lymphoma; 1996 Mar; 21(1-2):9-15. PubMed ID: 8907263
[TBL] [Abstract][Full Text] [Related]
22. Regulation of folate and one-carbon metabolism in mammalian cells. II. Effect of folylpoly-gamma-glutamate synthetase substrate specificity and level on folate metabolism and folylpoly-gamma-glutamate specificity of metabolic cycles of one-carbon metabolism.
Lowe KE; Osborne CB; Lin BF; Kim JS; Hsu JC; Shane B
J Biol Chem; 1993 Oct; 268(29):21665-73. PubMed ID: 8408019
[TBL] [Abstract][Full Text] [Related]
23. Folate analogues as substrates of mammalian folylpolyglutamate synthetase.
Schoo MM; Pristupa ZB; Vickers PJ; Scrimgeour KG
Cancer Res; 1985 Jul; 45(7):3034-41. PubMed ID: 3873989
[TBL] [Abstract][Full Text] [Related]
24. Biosynthesis of polyglutamates of folates.
Scrimgeour KG
Biochem Cell Biol; 1986 Jul; 64(7):667-74. PubMed ID: 3756000
[TBL] [Abstract][Full Text] [Related]
25. Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro.
Samuels LL; Moccio DM; Sirotnak FM
Cancer Res; 1985 Apr; 45(4):1488-95. PubMed ID: 3978616
[TBL] [Abstract][Full Text] [Related]
26. (6R,6S)-5,8,10-trideaza-5,6,7,8-tetrahydrofolate and 6(R,6S)-5,8,10-trideaza-5,6,7,8-tetrahydropteroyl-L-ornithine as potential antifolates and antitumor agents.
Rosowsky A; Forsch RA; Moran RG
J Med Chem; 1989 Mar; 32(3):709-15. PubMed ID: 2918520
[TBL] [Abstract][Full Text] [Related]
27. Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.
Westerhof GR; Schornagel JH; Kathmann I; Jackman AL; Rosowsky A; Forsch RA; Hynes JB; Boyle FT; Peters GJ; Pinedo HM
Mol Pharmacol; 1995 Sep; 48(3):459-71. PubMed ID: 7565626
[TBL] [Abstract][Full Text] [Related]
28. Inhibition of human liver folylpolyglutamate synthetase by non-gamma-glutamylatable antifolate analogs.
Clarke L; Rosowsky A; Waxman DJ
Mol Pharmacol; 1987 Jan; 31(1):122-7. PubMed ID: 3807889
[TBL] [Abstract][Full Text] [Related]
29. Synthetic polyglutamylation of dual-functional MTX ligands for enhanced combined cytotoxicity of poly(I:C) nanoplexes.
Lächelt U; Wittmann V; Müller K; Edinger D; Kos P; Höhn M; Wagner E
Mol Pharm; 2014 Aug; 11(8):2631-9. PubMed ID: 24754871
[TBL] [Abstract][Full Text] [Related]
30. Folylpoly-ɣ-glutamate synthetase association to the cytoskeleton: Implications to folate metabolon compartmentalization.
Stark M; Raz S; Assaraf YG
J Proteomics; 2021 May; 239():104169. PubMed ID: 33676037
[TBL] [Abstract][Full Text] [Related]
31. Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia.
Raz S; Stark M; Assaraf YG
Oncotarget; 2014 Oct; 5(19):9183-98. PubMed ID: 25229333
[TBL] [Abstract][Full Text] [Related]
32. Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate.
Sohn KJ; Smirnakis F; Moskovitz DN; Novakovic P; Yates Z; Lucock M; Croxford R; Kim YI
Gut; 2004 Dec; 53(12):1825-31. PubMed ID: 15542523
[TBL] [Abstract][Full Text] [Related]
33. Mechanism-based inhibitors of folylpoly-gamma-glutamate synthetase and gamma-glutamyl hydrolase: control of folylpoly-gamma-glutamate homeostasis as a drug target.
Coward JK; McGuire JJ
Vitam Horm; 2008; 79():347-73. PubMed ID: 18804701
[TBL] [Abstract][Full Text] [Related]
34. Recent advances in classical and non-classical antifolates as antitumor and antiopportunistic infection agents: Part II.
Gangjee A; Jain HD; Kurup S
Anticancer Agents Med Chem; 2008 Feb; 8(2):205-31. PubMed ID: 18288923
[TBL] [Abstract][Full Text] [Related]
35. The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis.
Assaraf YG
Drug Resist Updat; 2006; 9(4-5):227-46. PubMed ID: 17092765
[TBL] [Abstract][Full Text] [Related]
36. Design and synthesis of histidine analogues of folic acid and methotrexate as potential folylpolyglutamate synthetase inhibitors.
Mao Z; Pan J; Kalman TI
J Med Chem; 1996 Oct; 39(21):4340-4. PubMed ID: 8863812
[TBL] [Abstract][Full Text] [Related]
37. Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.
Jansen G; Mauritz RM; Assaraf YG; Sprecher H; Drori S; Kathmann I; Westerhof GR; Priest DG; Bunni M; Pinedo HM; Schornagel JH; Peters GJ
Adv Enzyme Regul; 1997; 37():59-76. PubMed ID: 9381986
[TBL] [Abstract][Full Text] [Related]
38. Roles of folylpoly-gamma-glutamate synthetase in therapeutics with tetrahydrofolate antimetabolites: an overview.
Moran RG
Semin Oncol; 1999 Apr; 26(2 Suppl 6):24-32. PubMed ID: 10598551
[TBL] [Abstract][Full Text] [Related]
39. Synthesis and biological activity of folic acid and methotrexate analogues containing L-threo-(2S,4S)-4-fluoroglutamic acid and DL-3,3-difluoroglutamic acid.
Hart BP; Haile WH; Licato NJ; Bolanowska WE; McGuire JJ; Coward JK
J Med Chem; 1996 Jan; 39(1):56-65. PubMed ID: 8568827
[TBL] [Abstract][Full Text] [Related]
40. Enzymatic synthesis of folate and antifolate polyglutamates with Escherichia coli folylpolyglutamate synthetase.
Hanlon MH; Ferone R; Weaver K; Ray P
Anal Biochem; 1994 Feb; 216(2):345-51. PubMed ID: 7513973
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
