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2. Development of a high-performance liquid chromatographic method for the analysis of enatiomer/enantiomer interaction in oxidative metabolism of bunitrolol in rat liver microsomes. Narimatsu S; Huang Y; Mizukami T; Masubuchi Y; Suzuki T Anal Biochem; 1994 Oct; 222(1):256-61. PubMed ID: 7856858 [TBL] [Abstract][Full Text] [Related]
3. Stereoselectivity in bunitrolol 4-hydroxylation in liver microsomes from marmosets and Japanese monkeys. Narimatsu S; Gotoh M; Masubuchi Y; Horie T; Ohmori S; Kitada M; Kageyama T; Asaoka K; Yamamoto I; Suzuki T Biol Pharm Bull; 1996 Nov; 19(11):1429-33. PubMed ID: 8951158 [TBL] [Abstract][Full Text] [Related]
4. Involvement of a cytochrome P4502D subfamily in human liver microsomal bunitrolol 4-hydroxylation. Narimatsu S; Masubuchi Y; Hosokawa S; Ohmori S; Kitada M; Suzuki T Biol Pharm Bull; 1994 Jun; 17(6):803-7. PubMed ID: 7951142 [TBL] [Abstract][Full Text] [Related]
5. Effect of 3-methylcholanthrene on bunitrolol metabolism. Kinetics and immunological studies on 4-hydroxylation of bunitrolol catalyzed by two species of cytochromes P450 in rat liver microsomes. Fujita S; Masuda M; Shimamoto Y; Hoshi H; Kariya S; Kazusaka A; Suzuki T Drug Metab Dispos; 1996 Feb; 24(2):254-9. PubMed ID: 8742239 [TBL] [Abstract][Full Text] [Related]
6. Oxidation of R(+)- and S(-)-carvedilol by rat liver microsomes. Evidence for stereoselective oxidation and characterization of the cytochrome P450 isozymes involved. Fujimaki M Drug Metab Dispos; 1994; 22(5):700-8. PubMed ID: 7835220 [TBL] [Abstract][Full Text] [Related]
7. Purification and characterization of a cytochrome P-450 isozyme catalyzing bunitrolol 4-hydroxylation in liver microsomes of male rats. Suzuki T; Narimatsu S; Fujita S; Masubuchi Y; Umeda S; Imaoka S; Funae Y Drug Metab Dispos; 1992; 20(3):367-73. PubMed ID: 1355709 [TBL] [Abstract][Full Text] [Related]
8. Involvement of CYP2D1 in the metabolism of carteolol by male rat liver microsomes. Umehara K; Kudo S; Odomi M Xenobiotica; 1997 Nov; 27(11):1121-9. PubMed ID: 9413916 [TBL] [Abstract][Full Text] [Related]
9. Bunitrolol metabolism and its inhibition by cimetidine. Ishida R; Fujita S; Suzuki T J Pharm Pharmacol; 1988 Jan; 40(1):64-5. PubMed ID: 2896780 [TBL] [Abstract][Full Text] [Related]
10. Inactivation of rat cytochrome P450 2D enzyme by a further metabolite of 4-hydroxypropranolol, the major and active metabolite of propranolol. Narimatsu S; Arai T; Masubuchi Y; Horie T; Hosokawa M; Ueno K; Kataoka H; Yamamoto S; Ishikawa T; Cho AK Biol Pharm Bull; 2001 Sep; 24(9):988-94. PubMed ID: 11558582 [TBL] [Abstract][Full Text] [Related]
11. Enantioselectivity of bunitrolol 4-hydroxylation is reversed by the change of an amino acid residue from valine to methionine at position 374 of cytochrome P450-2D6. Narimatsu S; Kato R; Horie T; Ono S; Tsutsui M; Yabusaki Y; Ohmori S; Kitada M; Ichioka T; Shimada N; Kato R; Ishikawa T Chirality; 1999; 11(1):1-9. PubMed ID: 9914647 [TBL] [Abstract][Full Text] [Related]
12. Differential roles of cytochromes P450 2D1, 2C11, and 1A1/2 in the hydroxylation of bufuralol by rat liver microsomes. Mimura M; Yamazaki H; Sugahara C; Hiroi T; Funae Y; Shimada T Biochem Pharmacol; 1994 Jun; 47(11):1957-63. PubMed ID: 7912070 [TBL] [Abstract][Full Text] [Related]
13. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes. Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340 [TBL] [Abstract][Full Text] [Related]
14. Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate. Masubuchi Y; Igarashi S; Suzuki T; Horie T; Narimatsu S J Pharmacol Exp Ther; 1996 Nov; 279(2):724-31. PubMed ID: 8930177 [TBL] [Abstract][Full Text] [Related]
15. Cytochrome P450 isozymes catalyzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroisoquinoline in rat liver microsomes. Suzuki T; Fujita S; Narimatsu S; Masubuchi Y; Tachibana M; Ohta S; Hirobe M FASEB J; 1992 Jan; 6(2):771-6. PubMed ID: 1537468 [TBL] [Abstract][Full Text] [Related]
16. Use of quinidine inhibition to define the role of the sparteine/debrisoquine cytochrome P450 in metoprolol oxidation by human liver microsomes. Otton SV; Crewe HK; Lennard MS; Tucker GT; Woods HF J Pharmacol Exp Ther; 1988 Oct; 247(1):242-7. PubMed ID: 3171974 [TBL] [Abstract][Full Text] [Related]
17. Metabolic kinetics of pseudoracemic propranolol in human liver microsomes. Enantioselectivity and quinidine inhibition. Marathe PH; Shen DD; Nelson WL Drug Metab Dispos; 1994; 22(2):237-47. PubMed ID: 8013280 [TBL] [Abstract][Full Text] [Related]
18. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A. Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860 [TBL] [Abstract][Full Text] [Related]
19. Substrate stereoselectivity and enantiomer/enantiomer interaction in propranolol metabolism in rat liver microsomes. Masubuchi Y; Yamamoto LA; Uesaka M; Fujita S; Narimatsu S; Suzuki T Biochem Pharmacol; 1993 Nov; 46(10):1759-65. PubMed ID: 8250961 [TBL] [Abstract][Full Text] [Related]
20. Stereoselectivity in the hydroxylation of propafenone enantiomers in mouse hepatic microsomes. Morita K; Mizuochi M; Yamaji A; Yokoyama T Biol Pharm Bull; 1994 Apr; 17(4):531-4. PubMed ID: 8069263 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]