BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 8967962)

  • 1. Overlapping drug interaction sites of human butyrylcholinesterase dissected by site-directed mutagenesis.
    Loewenstein-Lichtenstein Y; Glick D; Gluzman N; Sternfeld M; Zakut H; Soreq H
    Mol Pharmacol; 1996 Dec; 50(6):1423-31. PubMed ID: 8967962
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chimeric human cholinesterase. Identification of interaction sites responsible for recognition of acetyl- or butyrylcholinesterase-specific ligands.
    Loewenstein Y; Gnatt A; Neville LF; Soreq H
    J Mol Biol; 1993 Nov; 234(2):289-96. PubMed ID: 8230213
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histochemical demonstration of acetylcholinesterase activity in human Meibomian glands.
    Perra MT; Serra A; Sirigu P; Turno F
    Eur J Histochem; 1996; 40(1):39-44. PubMed ID: 8741098
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Does "butyrylization" of acetylcholinesterase through substitution of the six divergent aromatic amino acids in the active center gorge generate an enzyme mimic of butyrylcholinesterase?
    Kaplan D; Ordentlich A; Barak D; Ariel N; Kronman C; Velan B; Shafferman A
    Biochemistry; 2001 Jun; 40(25):7433-45. PubMed ID: 11412096
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors.
    Campiani G; Fattorusso C; Butini S; Gaeta A; Agnusdei M; Gemma S; Persico M; Catalanotti B; Savini L; Nacci V; Novellino E; Holloway HW; Greig NH; Belinskaya T; Fedorko JM; Saxena A
    J Med Chem; 2005 Mar; 48(6):1919-29. PubMed ID: 15771436
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The acetylcholinesterase inhibitor BW284c51 is a potent blocker of Torpedo nicotinic AchRs incorporated into the Xenopus oocyte membrane.
    Olivera-Bravo S; Ivorra I; Morales A
    Br J Pharmacol; 2005 Jan; 144(1):88-97. PubMed ID: 15644872
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Acetylcholinesterase and butyrylcholinesterase activity in the atria of the heart of adult albino rats.
    Slavíková J; Vlk J; Hlavicková V
    Physiol Bohemoslov; 1982; 31(5):407-14. PubMed ID: 6217470
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aspartate-70 to glycine substitution confers resistance to naturally occurring and synthetic anionic-site ligands on in-ovo produced human butyrylcholinesterase.
    Neville LF; Gnatt A; Loewenstein Y; Soreq H
    J Neurosci Res; 1990 Dec; 27(4):452-60. PubMed ID: 2079709
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conversion of acetylcholinesterase to butyrylcholinesterase: modeling and mutagenesis.
    Harel M; Sussman JL; Krejci E; Bon S; Chanal P; Massoulié J; Silman I
    Proc Natl Acad Sci U S A; 1992 Nov; 89(22):10827-31. PubMed ID: 1438284
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment.
    Komloova M; Musilek K; Horova A; Holas O; Dohnal V; Gunn-Moore F; Kuca K
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2505-9. PubMed ID: 21397501
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase.
    Saxena A; Redman AM; Jiang X; Lockridge O; Doctor BP
    Biochemistry; 1997 Dec; 36(48):14642-51. PubMed ID: 9398183
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Peripheral site acetylcholinesterase blockade induces RACK1-associated neuronal remodeling.
    Farchi N; Ofek K; Podoly E; Dong H; Xiang YY; Diamant S; Livnah O; Li J; Hochner B; Lu WY; Soreq H
    Neurodegener Dis; 2007; 4(2-3):171-84. PubMed ID: 17596712
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reduced acetylcholine receptor density, morphological remodeling, and butyrylcholinesterase activity can sustain muscle function in acetylcholinesterase knockout mice.
    Adler M; Manley HA; Purcell AL; Deshpande SS; Hamilton TA; Kan RK; Oyler G; Lockridge O; Duysen EG; Sheridan RE
    Muscle Nerve; 2004 Sep; 30(3):317-27. PubMed ID: 15318343
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specific targeting of acetylcholinesterase and butyrylcholinesterase recognition sites. Rational design of novel, selective, and highly potent cholinesterase inhibitors.
    Savini L; Gaeta A; Fattorusso C; Catalanotti B; Campiani G; Chiasserini L; Pellerano C; Novellino E; McKissic D; Saxena A
    J Med Chem; 2003 Jan; 46(1):1-4. PubMed ID: 12502352
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Unmasking tandem site interaction in human acetylcholinesterase. Substrate activation with a cationic acetanilide substrate.
    Johnson JL; Cusack B; Davies MP; Fauq A; Rosenberry TL
    Biochemistry; 2003 May; 42(18):5438-52. PubMed ID: 12731886
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Butyrylcholinesterase and the control of synaptic responses in acetylcholinesterase knockout mice.
    Girard E; Bernard V; Minic J; Chatonnet A; Krejci E; Molgó J
    Life Sci; 2007 May; 80(24-25):2380-5. PubMed ID: 17467011
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The aryl acylamidase activity is much more sensitive to Alzheimer drugs than the esterase activity of acetylcholinesterase in chicken embryonic brain.
    Rajesh RV; Chitra L; Layer PG; Boopathy R
    Biochimie; 2009 Sep; 91(9):1087-94. PubMed ID: 19607873
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nippostrongylus brasiliensis: characterisation of a somatic amphiphilic acetylcholinesterase with properties distinct from the secreted enzymes.
    Hussein AS; Grigg ME; Selkirk ME
    Exp Parasitol; 1999 Feb; 91(2):144-50. PubMed ID: 9990342
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Acetylcholinesterase active centre and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates.
    Kovarik Z; Radić Z; Berman HA; Simeon-Rudolf V; Reiner E; Taylor P
    Biochem J; 2003 Jul; 373(Pt 1):33-40. PubMed ID: 12665427
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stabilization of Torpedo californica acetylcholinesterase by reversible inhibitors.
    Weiner L; Shnyrov VL; Konstantinovskii L; Roth E; Ashani Y; Silman I
    Biochemistry; 2009 Jan; 48(3):563-74. PubMed ID: 19115961
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.