BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 8971830)

  • 1. Intrathecal ciliary neurotrophic factor delivery for treatment of amyotrophic lateral sclerosis (phase I trial).
    Penn RD; Kroin JS; York MM; Cedarbaum JM
    Neurosurgery; 1997 Jan; 40(1):94-9; discussion 99-100. PubMed ID: 8971830
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. ALS CNTF Treatment Study Group.
    Neurology; 1996 May; 46(5):1244-9. PubMed ID: 8628460
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. rhCNTF ALS Study Group.
    Miller RG; Petajan JH; Bryan WW; Armon C; Barohn RJ; Goodpasture JC; Hoagland RJ; Parry GJ; Ross MA; Stromatt SC
    Ann Neurol; 1996 Feb; 39(2):256-60. PubMed ID: 8967757
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients.
    Aebischer P; Schluep M; Déglon N; Joseph JM; Hirt L; Heyd B; Goddard M; Hammang JP; Zurn AD; Kato AC; Regli F; Baetge EE
    Nat Med; 1996 Jun; 2(6):696-9. PubMed ID: 8640564
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The pharmacokinetics of subcutaneously administered recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis: relation to parameters of the acute-phase response. The ALS CNTF Treatment Study (ACTS) Phase I-II Study Group.
    Clin Neuropharmacol; 1995 Dec; 18(6):500-14. PubMed ID: 8681311
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A phase I study of recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis. The ALS CNTF Treatment Study (ACTS) Phase I-II Study Group.
    Clin Neuropharmacol; 1995 Dec; 18(6):515-32. PubMed ID: 8681312
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Toxicity and tolerability of recombinant human ciliary neurotrophic factor in patients with amyotrophic lateral sclerosis.
    Miller RG; Bryan WW; Dietz MA; Munsat TL; Petajan JH; Smith SA; Goodpasture JC
    Neurology; 1996 Nov; 47(5):1329-31. PubMed ID: 8909453
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis.
    Ochs G; Penn RD; York M; Giess R; Beck M; Tonn J; Haigh J; Malta E; Traub M; Sendtner M; Toyka KV
    Amyotroph Lateral Scler Other Motor Neuron Disord; 2000 Jun; 1(3):201-6. PubMed ID: 11464953
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Safety, Tolerability, and Pharmacodynamics of Intrathecal Injection of Recombinant Human HGF (KP-100) in Subjects With Amyotrophic Lateral Sclerosis: A Phase I Trial.
    Warita H; Kato M; Asada R; Yamashita A; Hayata D; Adachi K; Aoki M
    J Clin Pharmacol; 2019 May; 59(5):677-687. PubMed ID: 30536581
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ciliary neurotrophic factor fused to a protein transduction domain retains full neuroprotective activity in the absence of cytokine-like side effects.
    Rezende AC; Peroni D; Vieira AS; Rogerio F; Talaisys RL; Costa FT; Langone F; Skaper SD; Negro A
    J Neurochem; 2009 Jun; 109(6):1680-90. PubMed ID: 19457136
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Therapeutic benefit of ciliary neurotrophic factor in progressive motor neuronopathy depends on the route of delivery.
    Haase G; Pettmann B; Bordet T; Villa P; Vigne E; Schmalbruch H; Kahn A
    Ann Neurol; 1999 Mar; 45(3):296-304. PubMed ID: 10072043
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis/motor neuron disease.
    Bongioanni P; Reali C; Sogos V
    Cochrane Database Syst Rev; 2004; 2004(3):CD004302. PubMed ID: 15266526
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ciliary neurotrophic factor: pharmacokinetics and acute-phase response in rat.
    Dittrich F; Thoenen H; Sendtner M
    Ann Neurol; 1994 Feb; 35(2):151-63. PubMed ID: 8109896
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ciliary neurotrophic factor infused intracerebroventricularly shows reduced catabolic effects when linked to the TAT protein transduction domain.
    Vieira AS; Rezende AC; Grigoletto J; Rogério F; Velloso LA; Skaper SD; Negro A; Langone F
    J Neurochem; 2009 Sep; 110(5):1557-66. PubMed ID: 19573019
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of an intrathecal immune response in amyotrophic lateral sclerosis patients implanted with encapsulated genetically engineered xenogeneic cells.
    Zurn AD; Henry H; Schluep M; Aubert V; Winkel L; Eilers B; Bachmann C; Aebischer P
    Cell Transplant; 2000; 9(4):471-84. PubMed ID: 11038064
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study.
    Miller TM; Pestronk A; David W; Rothstein J; Simpson E; Appel SH; Andres PL; Mahoney K; Allred P; Alexander K; Ostrow LW; Schoenfeld D; Macklin EA; Norris DA; Manousakis G; Crisp M; Smith R; Bennett CF; Bishop KM; Cudkowicz ME
    Lancet Neurol; 2013 May; 12(5):435-42. PubMed ID: 23541756
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The distribution of medication along the spinal canal after chronic intrathecal administration.
    Kroin JS; Ali A; York M; Penn RD
    Neurosurgery; 1993 Aug; 33(2):226-30; discussion 230. PubMed ID: 7690122
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gene therapy for amyotrophic lateral sclerosis (ALS) using a polymer encapsulated xenogenic cell line engineered to secrete hCNTF.
    Aebischer P; Pochon NA; Heyd B; Deglon N; Joseph JM; Zurn AD; Baetge EE; Hammang JP; Goddard M; Lysaght M; Kaplan F; Kato AC; Schluep M; Hirt L; Regli F; Porchet F; De Tribolet N
    Hum Gene Ther; 1996 May; 7(7):851-60. PubMed ID: 8860837
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ciliary neurotrophic factor inhibits brain and peripheral tumor necrosis factor production and, when coadministered with its soluble receptor, protects mice from lipopolysaccharide toxicity.
    Benigni F; Villa P; Demitri MT; Sacco S; Sipe JD; Lagunowich L; Panayotatos N; Ghezzi P
    Mol Med; 1995 Jul; 1(5):568-75. PubMed ID: 8529123
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse.
    Sagot Y; Tan SA; Baetge E; Schmalbruch H; Kato AC; Aebischer P
    Eur J Neurosci; 1995 Jun; 7(6):1313-22. PubMed ID: 7582105
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.