BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

369 related articles for article (PubMed ID: 8973188)

  • 1. Effects of alpha-deuteration and of aza and thia analogs of L-tryptophan on formation of intermediates in the reaction of Escherichia coli tryptophan indole-lyase.
    Sloan MJ; Phillips RS
    Biochemistry; 1996 Dec; 35(50):16165-73. PubMed ID: 8973188
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential effects of temperature and hydrostatic pressure on the formation of quinonoid intermediates from L-Trp and L-Met by H463F mutant Escherichia coli tryptophan indole-lyase.
    Phillips RS; Holtermann G
    Biochemistry; 2005 Nov; 44(43):14289-97. PubMed ID: 16245945
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The mechanism of Escherichia coli tryptophan indole-lyase: substituent effects on steady-state and pre-steady-state kinetic parameters for aryl-substituted tryptophan derivatives.
    Lee M; Phillips RS
    Bioorg Med Chem; 1995 Feb; 3(2):195-205. PubMed ID: 7796054
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reaction of indole and analogues with amino acid complexes of Escherichia coli tryptophan indole-lyase: detection of a new reaction intermediate by rapid-scanning stopped-flow spectrophotometry.
    Phillips RS
    Biochemistry; 1991 Jun; 30(24):5927-34. PubMed ID: 2043633
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Benzimidazole analogs of (L)-tryptophan are substrates and inhibitors of tryptophan indole lyase from Escherichia coli.
    Harris AP; Phillips RS
    FEBS J; 2013 Apr; 280(8):1807-17. PubMed ID: 23438036
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of aspartate-133 and histidine-458 in the mechanism of tryptophan indole-lyase from Proteus vulgaris.
    Demidkina TV; Zakomirdina LN; Kulikova VV; Dementieva IS; Faleev NG; Ronda L; Mozzarelli A; Gollnick PD; Phillips RS
    Biochemistry; 2003 Sep; 42(38):11161-9. PubMed ID: 14503866
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Replacement of lysine 269 by arginine in Escherichia coli tryptophan indole-lyase affects the formation and breakdown of quinonoid complexes.
    Phillips RS; Richter I; Gollnick P; Brzovic P; Dunn MF
    J Biol Chem; 1991 Oct; 266(28):18642-8. PubMed ID: 1917987
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of tyrosine ring fluorination on rates and equilibria of formation of intermediates in the reactions of carbon-carbon lyases.
    Phillips RS; Von Tersch RL; Secundo F
    Eur J Biochem; 1997 Mar; 244(2):658-63. PubMed ID: 9119037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 2-Methyl-L-tryptophan is a substrate of tryptophanase.
    Faleev NG; Gogoleva OI; Dementieva IS; Zakomirdina LN; Belikov VM
    Biochem Mol Biol Int; 1995 Apr; 35(5):1037-40. PubMed ID: 7549921
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Interaction of tryptophanase with substrate analogs].
    Zakomyrdina LN; Sakharova IS; Torchinskiĭ IuM
    Mol Biol (Mosk); 1988; 22(1):187-94. PubMed ID: 3287134
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism of binding of substrate analogues to tryptophan indole-lyase: studies using rapid-scanning and single-wavelength stopped-flow spectrophotometry.
    Phillips RS; Bender SL; Brzovic P; Dunn MF
    Biochemistry; 1990 Sep; 29(37):8608-14. PubMed ID: 2271544
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Catalytic properties of E. coli tryptophanase in a 50% aqueous solution of methanol and dimethylformamide].
    Faleev NG; Saporovskaia MB; Belikov VM; Sakharova IS; Zakomyrdina LN; Torchinskiĭ IuM
    Bioorg Khim; 1990 Aug; 16(8):1019-23. PubMed ID: 2285420
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Formation in vitro of hybrid dimers of H463F and Y74F mutant Escherichia coli tryptophan indole-lyase rescues activity with L-tryptophan.
    Phillips RS; Johnson N; Kamath AV
    Biochemistry; 2002 Mar; 41(12):4012-9. PubMed ID: 11900544
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The reaction of indole with the aminoacrylate intermediate of Salmonella typhimurium tryptophan synthase: observation of a primary kinetic isotope effect with 3-[(2)H]indole.
    Cash MT; Miles EW; Phillips RS
    Arch Biochem Biophys; 2004 Dec; 432(2):233-43. PubMed ID: 15542062
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The crystal structure of Proteus vulgaris tryptophan indole-lyase complexed with oxindolyl-L-alanine: implications for the reaction mechanism.
    Phillips RS; Buisman AA; Choi S; Hussaini A; Wood ZA
    Acta Crystallogr D Struct Biol; 2018 Aug; 74(Pt 8):748-759. PubMed ID: 30082510
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reaction of Pseudomonas fluorescens kynureninase with beta-benzoyl-L-alanine: detection of a new reaction intermediate and a change in rate-determining step.
    Gawandi VB; Liskey D; Lima S; Phillips RS
    Biochemistry; 2004 Mar; 43(11):3230-7. PubMed ID: 15023073
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cleavage of Escherichia coli tryptophan indole-lyase by trypsin at Lys406 affects the transmission of conformational changes associated with monovalent cation activation.
    Phillips RS; Doshi KJ
    Eur J Biochem; 1998 Jul; 255(2):508-15. PubMed ID: 9716394
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Properties of tryptophan indole-lyase from a piezophilic bacterium, Photobacterium profundum SS9.
    Phillips RS; Ghaffari R; Dinh P; Lima S; Bartlett D
    Arch Biochem Biophys; 2011 Feb; 506(1):35-41. PubMed ID: 21081107
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evidence of preorganization in quinonoid intermediate formation from L-Trp in H463F mutant Escherichia coli tryptophan indole-lyase from effects of pressure and pH.
    Phillips RS; Kalu U; Hay S
    Biochemistry; 2012 Aug; 51(33):6527-33. PubMed ID: 22852771
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aminoacrylate intermediates in the reaction of Citrobacter freundii tyrosine phenol-lyase.
    Phillips RS; Chen HY; Faleev NG
    Biochemistry; 2006 Aug; 45(31):9575-83. PubMed ID: 16878992
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.