These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 8978833)

  • 1. Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. CI-1011: an acyl sulfamate with unique cholesterol-lowering activity in animals fed noncholesterol-supplemented diets.
    Lee HT; Sliskovic DR; Picard JA; Roth BD; Wierenga W; Hicks JL; Bousley RF; Hamelehle KL; Homan R; Speyer C; Stanfield RL; Krause BR
    J Med Chem; 1996 Dec; 39(26):5031-4. PubMed ID: 8978833
    [No Abstract]   [Full Text] [Related]  

  • 2. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. synthesis and pharmacological activity of (+/-)-2-dodecyl-alpha-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5- acetamide and structurally related tetrazole amide derivatives.
    O'Brien PM; Sliskovic DR; Picard JA; Lee HT; Purchase CF; Roth BD; White AD; Anderson M; Mueller SB; Bocan T; Bousley R; Hamelehle KL; Homan R; Lee P; Krause BR; Reindel JF; Stanfield RL; Turluck D
    J Med Chem; 1996 Jun; 39(12):2354-66. PubMed ID: 8691430
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacology of the ACAT inhibitor avasimibe (CI-1011).
    Llaverías G; Laguna JC; Alegret M
    Cardiovasc Drug Rev; 2003; 21(1):33-50. PubMed ID: 12595916
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heterocyclic amides: inhibitors of acyl-CoA:cholesterol O-acyl transferase with hypocholesterolemic activity in several species and antiatherosclerotic activity in the rabbit.
    White AD; Purchase CF; Picard JA; Anderson MK; Mueller SB; Bocan TM; Bousley RF; Hamelehle KL; Krause BR; Lee P; Stanfield RL; Reindel JF
    J Med Chem; 1996 Sep; 39(20):3908-19. PubMed ID: 8831757
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacological profile of SMP-797, a novel acyl-coenzyme a: cholesterol acyltransferase inhibitor with inducible effect on the expression of low-density lipoprotein receptor.
    Ioriya K; Kino K; Horisawa S; Nishimura T; Muraoka M; Noguchi T; Ohashi N
    J Cardiovasc Pharmacol; 2006 Feb; 47(2):322-9. PubMed ID: 16495773
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Relationships between lipophilicity and biological activities in a series of indoline-based anti-oxidative acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors.
    Takahashi K; Kunishiro K; Kasai M; Miike T; Kurahashi K; Shirahase H
    Arzneimittelforschung; 2008; 58(12):666-72. PubMed ID: 19202739
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7alpha-hydroxylase in cultured rat hepatocytes and in vivo in the rat.
    Post SM; Zoeteweij JP; Bos MH; de Wit EC; Havinga R; Kuipers F; Princen HM
    Hepatology; 1999 Aug; 30(2):491-500. PubMed ID: 10421659
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT) as hypocholesterolemic agents: synthesis and structure-activity relationships of novel series of sulfonamides, acylphosphonamides and acylphosphoramidates.
    Lee HT; Roark WH; Picard JA; Sliskovic DR; Roth BD; Stanfield RL; Hamelehle KL; Bousley RF; Krause BR
    Bioorg Med Chem Lett; 1998 Feb; 8(3):289-94. PubMed ID: 9871672
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Divergent pharmacologic activities of PD 132301-2 and CL 277,082, urea inhibitors of acyl-CoA:cholesterol acyltransferase.
    Krause BR; Black A; Bousley R; Essenburg A; Cornicelli J; Holmes A; Homan R; Kieft K; Sekerke C; Shaw-Hes MK
    J Pharmacol Exp Ther; 1993 Nov; 267(2):734-43. PubMed ID: 8246149
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heterocyclic ureas: inhibitors of acyl-CoA:cholesterol O-acyltransferase as hypocholesterolemic agents.
    White AD; Creswell MW; Chucholowski AW; Blankley CJ; Wilson MW; Bousley RF; Essenburg AD; Hamelehle KL; Krause BR; Stanfield RL; Dominick MA; Neub M
    J Med Chem; 1996 Oct; 39(22):4382-95. PubMed ID: 8893833
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The ACAT inhibitor avasimibe reduces macrophages and matrix metalloproteinase expression in atherosclerotic lesions of hypercholesterolemic rabbits.
    Bocan TM; Krause BR; Rosebury WS; Mueller SB; Lu X; Dagle C; Major T; Lathia C; Lee H
    Arterioscler Thromb Vasc Biol; 2000 Jan; 20(1):70-9. PubMed ID: 10634802
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibitors of acyl CoA:cholesterol acyltransferase.
    Vaccaro W; Amore C; Berger J; Burrier R; Clader J; Davis H; Domalski M; Fevig T; Salisbury B; Sher R
    J Med Chem; 1996 Apr; 39(8):1704-19. PubMed ID: 8648610
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological activity of novel 4-phenyl-1,8-naphthyridin-2(1H)-on-3-yl ureas: potent acyl-CoA:cholesterol acyltransferase inhibitor with improved aqueous solubility.
    Ban H; Muraoka M; Ioriya K; Ohashi N
    Bioorg Med Chem Lett; 2006 Jan; 16(1):44-8. PubMed ID: 16242323
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of SMP-500, a novel acyl-coA:cholesterol acyltransferase inhibitor, on the cholesterol esterification and its hypocholesterolemic properties.
    Ioriya K; Noguchi T; Muraoka M; Fujita K; Shimizu H; Ohashi N
    Pharmacology; 2002 May; 65(1):18-25. PubMed ID: 11901297
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Acyl-CoA: cholesterol acyltransferase inhibitory activity of ginseng sapogenins, produced from the ginseng saponins.
    Kwon BM; Kim MK; Baek NI; Kim DS; Park JD; Kim YK; Lee HK; Kim SI
    Bioorg Med Chem Lett; 1999 May; 9(10):1375-8. PubMed ID: 10360739
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Acyl-CoA:cholesterol O-acyl transferase (ACAT) inhibitors. 1. 2-(Alkylthio)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT.
    Harris NV; Smith C; Ashton MJ; Bridge AW; Bush RC; Coffee EC; Dron DI; Harper MF; Lythgoe DJ; Newton CG
    J Med Chem; 1992 Nov; 35(23):4384-92. PubMed ID: 1447739
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibitors of acyl-CoA: cholesterol acyltransferase. II. Preparation and hypocholesterolemic activity of optically active dibenz[b,e]oxepin-11-carboxanilides.
    Kumazawa T; Yanase M; Shirakura S; Ohishi E; Yamada K; Matsumiya S; Kono M
    Chem Pharm Bull (Tokyo); 1996 Jan; 44(1):222-5. PubMed ID: 8582041
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitors of acyl-CoA:cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. 8. Incorporation of amide or amine functionalities into a series of disubstituted ureas and carbamates. Effects on ACAT inhibition in vitro and efficacy in vivo.
    O'Brien PM; Sliskovic DR; Blankley CJ; Roth BD; Wilson MW; Hamelehle KL; Krause BR; Stanfield RL
    J Med Chem; 1994 Jun; 37(12):1810-22. PubMed ID: 8021920
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potent inhibitors of acyl-CoA:cholesterol acyltransferase. 2. Structure-activity relationships of novel N-(2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)amides.
    Kataoka K; Shiota T; Takeyasu T; Minoshima T; Watanabe K; Tanaka H; Mochizuki T; Taneda K; Ota M; Tanabe H; Yamaguchi H
    J Med Chem; 1996 Mar; 39(6):1262-70. PubMed ID: 8632433
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acyl-CoA:Cholesterol O-acyltransferase (ACAT) inhibitors. 2. 2-(1,3-Dioxan-2-yl)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT.
    Astles PC; Ashton MJ; Bridge AW; Harris NV; Hart TW; Parrott DP; Porter B; Riddell D; Smith C; Williams RJ
    J Med Chem; 1996 Mar; 39(7):1423-32. PubMed ID: 8691472
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.