BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

291 related articles for article (PubMed ID: 8986763)

  • 1. Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells.
    Marshak S; Totary H; Cerasi E; Melloul D
    Proc Natl Acad Sci U S A; 1996 Dec; 93(26):15057-62. PubMed ID: 8986763
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site.
    Serup P; Petersen HV; Pedersen EE; Edlund H; Leonard J; Petersen JS; Larsson LI; Madsen OD
    Biochem J; 1995 Sep; 310 ( Pt 3)(Pt 3):997-1003. PubMed ID: 7575438
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transforming growth factor beta induction of insulin gene expression is mediated by pancreatic and duodenal homeobox gene-1 in rat insulinoma cells.
    Sayo Y; Hosokawa H; Imachi H; Murao K; Sato M; Wong NC; Ishida T; Takahara J
    Eur J Biochem; 2000 Feb; 267(4):971-8. PubMed ID: 10672004
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The PDX-1 activation domain provides specific functions necessary for transcriptional stimulation in pancreatic beta-cells.
    Peshavaria M; Cissell MA; Henderson E; Petersen HV; Stein R
    Mol Endocrinol; 2000 Dec; 14(12):1907-17. PubMed ID: 11117522
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes.
    Petersen HV; Serup P; Leonard J; Michelsen BK; Madsen OD
    Proc Natl Acad Sci U S A; 1994 Oct; 91(22):10465-9. PubMed ID: 7937976
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters.
    Melloul D; Ben-Neriah Y; Cerasi E
    Proc Natl Acad Sci U S A; 1993 May; 90(9):3865-9. PubMed ID: 8483904
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor.
    Waeber G; Thompson N; Nicod P; Bonny C
    Mol Endocrinol; 1996 Nov; 10(11):1327-34. PubMed ID: 8923459
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reconstitution of glucotoxic HIT-T15 cells with somatostatin transcription factor-1 partially restores insulin promoter activity.
    Harmon JS; Tanaka Y; Olson LK; Robertson RP
    Diabetes; 1998 Jun; 47(6):900-4. PubMed ID: 9604866
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional regions of the homeodomain protein IDX-1 required for transactivation of the rat somatostatin gene.
    Lu M; Miller C; Habener JF
    Endocrinology; 1996 Jul; 137(7):2959-67. PubMed ID: 8770920
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells.
    Watada H; Kajimoto Y; Umayahara Y; Matsuoka T; Kaneto H; Fujitani Y; Kamada T; Kawamori R; Yamasaki Y
    Diabetes; 1996 Nov; 45(11):1478-88. PubMed ID: 8866550
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene.
    Kataoka K; Han SI; Shioda S; Hirai M; Nishizawa M; Handa H
    J Biol Chem; 2002 Dec; 277(51):49903-10. PubMed ID: 12368292
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression.
    Olson LK; Sharma A; Peshavaria M; Wright CV; Towle HC; Rodertson RP; Stein R
    Proc Natl Acad Sci U S A; 1995 Sep; 92(20):9127-31. PubMed ID: 7568086
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of PCIF1, a POZ domain protein that inhibits PDX-1 (MODY4) transcriptional activity.
    Liu A; Desai BM; Stoffers DA
    Mol Cell Biol; 2004 May; 24(10):4372-83. PubMed ID: 15121856
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of the insulin gene by glucose: stimulation of trans-activation potency of human PDX-1 N-terminal domain.
    Shushan EB; Cerasi E; Melloul D
    DNA Cell Biol; 1999 Jun; 18(6):471-9. PubMed ID: 10390156
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hedgehog signaling regulation of homeodomain protein islet duodenum homeobox-1 expression in pancreatic beta-cells.
    Thomas MK; Lee JH; Rastalsky N; Habener JF
    Endocrinology; 2001 Mar; 142(3):1033-40. PubMed ID: 11181516
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glucose regulates islet amyloid polypeptide gene transcription in a PDX1- and calcium-dependent manner.
    Macfarlane WM; Campbell SC; Elrick LJ; Oates V; Bermano G; Lindley KJ; Aynsley-Green A; Dunne MJ; James RF; Docherty K
    J Biol Chem; 2000 May; 275(20):15330-5. PubMed ID: 10748090
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transfection of pancreatic-derived beta-cells with a minigene encoding for human glucagon-like peptide-1 regulates glucose-dependent insulin synthesis and secretion.
    Hui H; Yu R; Bousquet C; Perfetti R
    Endocrinology; 2002 Sep; 143(9):3529-39. PubMed ID: 12193567
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bridge-1, a novel PDZ-domain coactivator of E2A-mediated regulation of insulin gene transcription.
    Thomas MK; Yao KM; Tenser MS; Wong GG; Habener JF
    Mol Cell Biol; 1999 Dec; 19(12):8492-504. PubMed ID: 10567574
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interactions between areas I and II direct pdx-1 expression specifically to islet cell types of the mature and developing pancreas.
    Van Velkinburgh JC; Samaras SE; Gerrish K; Artner I; Stein R
    J Biol Chem; 2005 Nov; 280(46):38438-44. PubMed ID: 16147997
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator.
    Poitout V; Olson LK; Robertson RP
    J Clin Invest; 1996 Feb; 97(4):1041-6. PubMed ID: 8613527
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.