These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 8987974)

  • 1. X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis.
    Scolnick LR; Christianson DW
    Biochemistry; 1996 Dec; 35(51):16429-34. PubMed ID: 8987974
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disruption of the active site solvent network in carbonic anhydrase II decreases the efficiency of proton transfer.
    Jackman JE; Merz KM; Fierke CA
    Biochemistry; 1996 Dec; 35(51):16421-8. PubMed ID: 8987973
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-based design of an intramolecular proton transfer site in murine carbonic anhydrase V.
    Heck RW; Boriack-Sjodin PA; Qian M; Tu C; Christianson DW; Laipis PJ; Silverman DN
    Biochemistry; 1996 Sep; 35(36):11605-11. PubMed ID: 8794740
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The catalytic properties of murine carbonic anhydrase VII.
    Earnhardt JN; Qian M; Tu C; Lakkis MM; Bergenhem NC; Laipis PJ; Tashian RE; Silverman DN
    Biochemistry; 1998 Jul; 37(30):10837-45. PubMed ID: 9692974
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II.
    Fisher Z; Hernandez Prada JA; Tu C; Duda D; Yoshioka C; An H; Govindasamy L; Silverman DN; McKenna R
    Biochemistry; 2005 Feb; 44(4):1097-105. PubMed ID: 15667203
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histidine --> carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity.
    Lesburg CA; Huang C; Christianson DW; Fierke CA
    Biochemistry; 1997 Dec; 36(50):15780-91. PubMed ID: 9398308
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II.
    Fisher SZ; Tu C; Bhatt D; Govindasamy L; Agbandje-McKenna M; McKenna R; Silverman DN
    Biochemistry; 2007 Mar; 46(12):3803-13. PubMed ID: 17330962
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Carbonic anhydrase activators: X-ray crystallographic and spectroscopic investigations for the interaction of isozymes I and II with histamine.
    Briganti F; Mangani S; Orioli P; Scozzafava A; Vernaglione G; Supuran CT
    Biochemistry; 1997 Aug; 36(34):10384-92. PubMed ID: 9265618
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Solvent-mediated proton transfer in catalysis by carbonic anhydrase.
    Silverman DN; McKenna R
    Acc Chem Res; 2007 Aug; 40(8):669-75. PubMed ID: 17550224
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Intramolecular proton transfer from multiple sites in catalysis by murine carbonic anhydrase V.
    Earnhardt JN; Qian M; Tu C; Laipis PJ; Silverman DN
    Biochemistry; 1998 May; 37(20):7649-55. PubMed ID: 9585580
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glutamate and aspartate as proton shuttles in mutants of carbonic anhydrase.
    Qian M; Tu C; Earnhardt JN; Laipis PJ; Silverman DN
    Biochemistry; 1997 Dec; 36(50):15758-64. PubMed ID: 9398305
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural consequences of redesigning a protein-zinc binding site.
    Ippolito JA; Christianson DW
    Biochemistry; 1994 Dec; 33(51):15241-9. PubMed ID: 7803386
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism.
    Fisher SZ; Maupin CM; Budayova-Spano M; Govindasamy L; Tu C; Agbandje-McKenna M; Silverman DN; Voth GA; McKenna R
    Biochemistry; 2007 Mar; 46(11):2930-7. PubMed ID: 17319692
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural and kinetic analysis of proton shuttle residues in the active site of human carbonic anhydrase III.
    Elder I; Fisher Z; Laipis PJ; Tu C; McKenna R; Silverman DN
    Proteins; 2007 Jul; 68(1):337-43. PubMed ID: 17427958
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors.
    Smith GM; Alexander RS; Christianson DW; McKeever BM; Ponticello GS; Springer JP; Randall WC; Baldwin JJ; Habecker CN
    Protein Sci; 1994 Jan; 3(1):118-25. PubMed ID: 8142888
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proton transfer in a Thr200His mutant of human carbonic anhydrase II.
    Bhatt D; Tu C; Fisher SZ; Hernandez Prada JA; McKenna R; Silverman DN
    Proteins; 2005 Nov; 61(2):239-45. PubMed ID: 16106378
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human carbonic anhydrase III: structural and kinetic study of catalysis and proton transfer.
    Duda DM; Tu C; Fisher SZ; An H; Yoshioka C; Govindasamy L; Laipis PJ; Agbandje-McKenna M; Silverman DN; McKenna R
    Biochemistry; 2005 Aug; 44(30):10046-53. PubMed ID: 16042381
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII, and XIV with l- and d-histidine and crystallographic analysis of their adducts with isoform II: engineering proton-transfer processes within the active site of an enzyme.
    Temperini C; Scozzafava A; Vullo D; Supuran CT
    Chemistry; 2006 Sep; 12(27):7057-66. PubMed ID: 16807956
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of carbonic anhydrase from Neisseria gonorrhoeae and its complex with the inhibitor acetazolamide.
    Huang S; Xue Y; Sauer-Eriksson E; Chirica L; Lindskog S; Jonsson BH
    J Mol Biol; 1998; 283(1):301-10. PubMed ID: 9761692
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Catalysis and inhibition of human carbonic anhydrase IV.
    Baird TT; Waheed A; Okuyama T; Sly WS; Fierke CA
    Biochemistry; 1997 Mar; 36(9):2669-78. PubMed ID: 9054574
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.