BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 8987996)

  • 1. Elucidation of the role of Arg 110 of murine leukemia virus reverse transcriptase in the catalytic mechanism: biochemical characterization of its mutant enzymes.
    Chowdhury K; Kaushik N; Pandey VN; Modak MJ
    Biochemistry; 1996 Dec; 35(51):16610-20. PubMed ID: 8987996
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tyrosine 222, a member of the YXDD motif of MuLV RT, is catalytically essential and is a major component of the fidelity center.
    Kaushik N; Singh K; Alluru I; Modak MJ
    Biochemistry; 1999 Mar; 38(9):2617-27. PubMed ID: 10052931
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biochemical analysis of catalytically crucial aspartate mutants of human immunodeficiency virus type 1 reverse transcriptase.
    Kaushik N; Rege N; Yadav PN; Sarafianos SG; Modak MJ; Pandey VN
    Biochemistry; 1996 Sep; 35(36):11536-46. PubMed ID: 8794733
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain.
    Najmudin S; Coté ML; Sun D; Yohannan S; Montano SP; Gu J; Georgiadis MM
    J Mol Biol; 2000 Feb; 296(2):613-32. PubMed ID: 10669612
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutations in the RNase H primer grip domain of murine leukemia virus reverse transcriptase decrease efficiency and accuracy of plus-strand DNA transfer.
    Mbisa JL; Nikolenko GN; Pathak VK
    J Virol; 2005 Jan; 79(1):419-27. PubMed ID: 15596835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Significance of the O-helix residues of Escherichia coli DNA polymerase I in DNA synthesis: dynamics of the dNTP binding pocket.
    Kaushik N; Pandey VN; Modak MJ
    Biochemistry; 1996 Jun; 35(22):7256-66. PubMed ID: 8679555
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of glutamine-151 of human immunodeficiency virus type-1 reverse transcriptase in RNA-directed DNA synthesis.
    Kaushik N; Harris D; Rege N; Modak MJ; Yadav PN; Pandey VN
    Biochemistry; 1997 Nov; 36(47):14430-8. PubMed ID: 9398161
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis.
    Pandey VN; Kaushik N; Rege N; Sarafianos SG; Yadav PN; Modak MJ
    Biochemistry; 1996 Feb; 35(7):2168-79. PubMed ID: 8652558
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Y586F mutation in murine leukemia virus reverse transcriptase decreases fidelity of DNA synthesis in regions associated with adenine-thymine tracts.
    Zhang WH; Svarovskaia ES; Barr R; Pathak VK
    Proc Natl Acad Sci U S A; 2002 Jul; 99(15):10090-5. PubMed ID: 12119402
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Substitution of Asp114 or Arg116 in the fingers domain of moloney murine leukemia virus reverse transcriptase affects interactions with the template-primer resulting in decreased processivity.
    Gu J; Villanueva RA; Snyder CS; Roth MJ; Georgiadis MM
    J Mol Biol; 2001 Jan; 305(2):341-59. PubMed ID: 11124910
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Polycitone A, a novel and potent general inhibitor of retroviral reverse transcriptases and cellular DNA polymerases.
    Loya S; Rudi A; Kashman Y; Hizi A
    Biochem J; 1999 Nov; 344 Pt 1(Pt 1):85-92. PubMed ID: 10548537
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA polymerase beta: pre-steady-state kinetic analysis and roles of arginine-283 in catalysis and fidelity.
    Werneburg BG; Ahn J; Zhong X; Hondal RJ; Kraynov VS; Tsai MD
    Biochemistry; 1996 Jun; 35(22):7041-50. PubMed ID: 8679529
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutational analysis of Lys65 of HIV-1 reverse transcriptase.
    Sluis-Cremer N; Arion D; Kaushik N; Lim H; Parniak MA
    Biochem J; 2000 May; 348 Pt 1(Pt 1):77-82. PubMed ID: 10794716
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of the role of glutamine 190 in the catalytic mechanism of murine leukemia virus reverse transcriptase.
    Jin J; Kaushik N; Singh K; Modak MJ
    J Biol Chem; 1999 Jul; 274(30):20861-8. PubMed ID: 10409628
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lysine 152 of MuLV reverse transcriptase is required for the integrity of the active site.
    Shi Q; Singh K; Srivastava A; Kaushik N; Modak MJ
    Biochemistry; 2002 Dec; 41(50):14831-42. PubMed ID: 12475231
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Studies on the effects of truncating alpha-helix E' of p66 human immunodeficiency virus type 1 reverse transcriptase on template-primer binding and fidelity of DNA synthesis.
    Menéndez-Arias L
    Biochemistry; 1998 Nov; 37(47):16636-44. PubMed ID: 9843431
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional roles of carboxylate residues comprising the DNA polymerase active site triad of Ty3 reverse transcriptase.
    Bibillo A; Lener D; Klarmann GJ; Le Grice SF
    Nucleic Acids Res; 2005; 33(1):171-81. PubMed ID: 15647500
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis.
    Weiss KK; Chen R; Skasko M; Reynolds HM; Lee K; Bambara RA; Mansky LM; Kim B
    Biochemistry; 2004 Apr; 43(15):4490-500. PubMed ID: 15078095
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amino acid substitutions away from the RNase H catalytic site increase the thermal stability of Moloney murine leukemia virus reverse transcriptase through RNase H inactivation.
    Konishi A; Hisayoshi T; Yokokawa K; Barrioluengo V; Menéndez-Arias L; Yasukawa K
    Biochem Biophys Res Commun; 2014 Nov; 454(2):269-74. PubMed ID: 25450388
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dynamic copy choice: steady state between murine leukemia virus polymerase and polymerase-dependent RNase H activity determines frequency of in vivo template switching.
    Hwang CK; Svarovskaia ES; Pathak VK
    Proc Natl Acad Sci U S A; 2001 Oct; 98(21):12209-14. PubMed ID: 11593039
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.