BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

309 related articles for article (PubMed ID: 8988000)

  • 1. Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2'-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chirality.
    Moriya M; Spiegel S; Fernandes A; Amin S; Liu T; Geacintov N; Grollman AP
    Biochemistry; 1996 Dec; 35(51):16646-51. PubMed ID: 8988000
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutagenic potential of stereoisomeric bay region (+)- and (-)-cis-anti-benzo[a]pyrene diol epoxide-N2-2'-deoxyguanosine adducts in Escherichia coli and simian kidney cells.
    Fernandes A; Liu T; Amin S; Geacintov NE; Grollman AP; Moriya M
    Biochemistry; 1998 Jul; 37(28):10164-72. PubMed ID: 9665722
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene.
    Dong H; Bonala RR; Suzuki N; Johnson F; Grollman AP; Shibutani S
    Biochemistry; 2004 Dec; 43(50):15922-8. PubMed ID: 15595848
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeted A --> T and G --> T mutations induced by site-specific deoxyadenosine and deoxyguanosine adducts, respectively, from the (+)-anti-diol epoxide of dibenz[a,j]anthracene in M13mp7L2.
    Min Z; Gill RD; Cortez C; Harvey RG; Loechler EL; DiGiovanni J
    Biochemistry; 1996 Apr; 35(13):4128-38. PubMed ID: 8672448
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Formation of diastereomeric benzo[a]pyrene diol epoxide-guanine adducts in p53 gene-derived DNA sequences.
    Matter B; Wang G; Jones R; Tretyakova N
    Chem Res Toxicol; 2004 Jun; 17(6):731-41. PubMed ID: 15206894
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and characterization of adducts derived from the syn-diastereomer of benzo[a]pyrene 7,8-dihydrodiol 9,10-epoxide and the 5'-d(CCTATAGATATCC) oligonucleotide.
    Pontén I; Seidel A; Gräslund A; Jernström B
    Chem Res Toxicol; 1996; 9(1):188-96. PubMed ID: 8924590
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Implications of cytosine methylation on (+)-anti-Benzo[a]pyrene 7, 8-dihydrodiol 9,10-epoxide N(2)-dG adduct formation in 5'-d(CGT), 5'-d(CGA), and 5'-d(CGC) sequence contexts of single- and double-stranded oligonucleotides.
    Pradhan P; Gräslund A; Seidel A; Jernström B
    Chem Res Toxicol; 1999 Sep; 12(9):816-21. PubMed ID: 10490503
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
    Feng B; Gorin A; Kolbanovskiy A; Hingerty BE; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1997 Nov; 36(45):13780-90. PubMed ID: 9374854
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stereospecific differences in repair by human cell extracts of synthesized oligonucleotides containing trans-opened 7,8,9, 10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-dG adduct stereoisomers located within the human K-ras codon 12 sequence.
    Custer L; Zajc B; Sayer JM; Cullinane C; Phillips DR; Cheh AM; Jerina DM; Bohr VA; Mazur SJ
    Biochemistry; 1999 Jan; 38(2):569-81. PubMed ID: 9888796
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Spectral differentiation and immunoaffinity capillary electrophoresis separation of enantiomeric benzo(a)pyrene diol epoxide-derived DNA adducts.
    Miksa B; Chinnappan R; Dang NC; Reppert M; Matter B; Tretyakova N; Grubor NM; Jankowiak R
    Chem Res Toxicol; 2007 Aug; 20(8):1192-9. PubMed ID: 17630708
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sequence specific mutagenesis of the major (+)-anti-benzo[a]pyrene diol epoxide-DNA adduct at a mutational hot spot in vitro and in Escherichia coli cells.
    Hanrahan CJ; Bacolod MD; Vyas RR; Liu T; Geacintov NE; Loechler EL; Basu AK
    Chem Res Toxicol; 1997 Apr; 10(4):369-77. PubMed ID: 9114972
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.
    Yoon JH; Smith LE; Feng Z; Tang M; Lee CS; Pfeifer GP
    Cancer Res; 2001 Oct; 61(19):7110-7. PubMed ID: 11585742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Base sequence-dependent bends in site-specific benzo[a]pyrene diol epoxide-modified oligonucleotide duplexes.
    Liu T; Xu J; Tsao H; Li B; Xu R; Yang C; Amin S; Moriya M; Geacintov NE
    Chem Res Toxicol; 1996; 9(1):255-61. PubMed ID: 8924600
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quantitative study of stereospecific binding of monoclonal antibody to anti-benzo(a)pyrene diol epoxide-N(2)-dG adducts by capillary electrophoresis immunoassay.
    Wang C; Li T; Wang Z; Feng F; Wang H
    J Chromatogr A; 2010 Apr; 1217(15):2254-61. PubMed ID: 20223464
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sequence context profoundly influences the mutagenic potency of trans-opened benzo[a]pyrene 7,8-diol 9,10-epoxide-purine nucleoside adducts in site-specific mutation studies.
    Page JE; Zajc B; Oh-hara T; Lakshman MK; Sayer JM; Jerina DM; Dipple A
    Biochemistry; 1998 Jun; 37(25):9127-37. PubMed ID: 9636059
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutagenesis studies with four stereoisomeric N2-dG benzo[a]pyrene adducts in the identical 5'-CGC sequence used in NMR studies: G->T mutations dominate in each case.
    Seo KY; Nagalingam A; Tiffany M; Loechler EL
    Mutagenesis; 2005 Nov; 20(6):441-8. PubMed ID: 16311255
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impact of the stereochemistry of benzo[a]pyrene 7,8-dihydrodiol 9,10-epoxide-deoxyadenosine adducts on resistance to digestion by phosphodiesterases I and II and translesion synthesis with HIV-1 reverse transcriptase.
    Chary P; Lloyd RS
    Chem Res Toxicol; 1996 Mar; 9(2):409-17. PubMed ID: 8839043
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interference of benzo[a]pyrene diol epoxide-deoxyguanosine adducts in a GC box with binding of the transcription factor Sp1.
    MacLeod MC; Powell KL; Kuzmin VA; Kolbanovskiy A; Geacintov NE
    Mol Carcinog; 1996 May; 16(1):44-52. PubMed ID: 8634093
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ability of adducts formed in a shuttle vector by reactive metabolites of 1-nitropyrene and benzo(a)pyrene to induce mutations when the plasmid replicates in human cells.
    Maher VM; Yang JL; McCormick JJ
    Acta Biol Hung; 1990; 41(1-3):173-86. PubMed ID: 2128787
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutagenic properties of 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene, a persistent acetylaminofluorene-derived DNA adduct in mammalian cells.
    Yasui M; Dong H; Bonala RR; Suzuki N; Ohmori H; Hanaoka F; Johnson F; Grollman AP; Shibutani S
    Biochemistry; 2004 Nov; 43(47):15005-13. PubMed ID: 15554708
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.