These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 8993329)

  • 1. A novel metalloprotease in rat brain cleaves the amyloid precursor protein of Alzheimer's disease generating amyloidogenic fragments.
    Mok SS; Evin G; Li QX; Smith AI; Beyreuther K; Masters CL; Small DH
    Biochemistry; 1997 Jan; 36(1):156-63. PubMed ID: 8993329
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
    Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
    Nunan J; Williamson NA; Hill AF; Sernee MF; Masters CL; Small DH
    J Neurosci Res; 2003 Nov; 74(3):378-85. PubMed ID: 14598314
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.
    Vingtdeux V; Hamdane M; Gompel M; Bégard S; Drobecq H; Ghestem A; Grosjean ME; Kostanjevecki V; Grognet P; Vanmechelen E; Buée L; Delacourte A; Sergeant N
    Neurobiol Dis; 2005 Nov; 20(2):625-37. PubMed ID: 15936948
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 6. P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.
    Meredith JE; Thompson LA; Toyn JH; Marcin L; Barten DM; Marcinkeviciene J; Kopcho L; Kim Y; Lin A; Guss V; Burton C; Iben L; Polson C; Cantone J; Ford M; Drexler D; Fiedler T; Lentz KA; Grace JE; Kolb J; Corsa J; Pierdomenico M; Jones K; Olson RE; Macor JE; Albright CF
    J Pharmacol Exp Ther; 2008 Aug; 326(2):502-13. PubMed ID: 18499745
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase.
    Parvathy S; Hussain I; Karran EH; Turner AJ; Hooper NM
    Biochemistry; 1998 Feb; 37(6):1680-5. PubMed ID: 9484239
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.
    Yan R; Bienkowski MJ; Shuck ME; Miao H; Tory MC; Pauley AM; Brashier JR; Stratman NC; Mathews WR; Buhl AE; Carter DB; Tomasselli AG; Parodi LA; Heinrikson RL; Gurney ME
    Nature; 1999 Dec; 402(6761):533-7. PubMed ID: 10591213
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of huperzine A on amyloid precursor protein processing and beta-amyloid generation in human embryonic kidney 293 APP Swedish mutant cells.
    Peng Y; Jiang L; Lee DY; Schachter SC; Ma Z; Lemere CA
    J Neurosci Res; 2006 Sep; 84(4):903-11. PubMed ID: 16862548
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells.
    Parvathy S; Hussain I; Karran EH; Turner AJ; Hooper NM
    Biochemistry; 1999 Jul; 38(30):9728-34. PubMed ID: 10423252
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased release of an amyloidogenic C-terminal Alzheimer amyloid precursor protein fragment from stressed PC-12 cells.
    Baskin F; Rosenberg RN; Greenberg BD
    J Neurosci Res; 1991 May; 29(1):127-32. PubMed ID: 1909380
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor.
    Miyazaki K; Hasegawa M; Funahashi K; Umeda M
    Nature; 1993 Apr; 362(6423):839-41. PubMed ID: 8479521
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of the high affinity heparin binding site of the Alzheimer's disease beta A4 amyloid precursor protein (APP) and its enhancement by zinc(II).
    Multhaup G; Mechler H; Masters CL
    J Mol Recognit; 1995; 8(4):247-57. PubMed ID: 8588942
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BACE inhibitor reduces APP-beta-C-terminal fragment accumulation in axonal swellings of okadaic acid-induced neurodegeneration.
    Yoon SY; Choi JE; Yoon JH; Huh JW; Kim DH
    Neurobiol Dis; 2006 May; 22(2):435-44. PubMed ID: 16480887
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of Abeta production by NF-kappaB inhibitors.
    Paris D; Patel N; Quadros A; Linan M; Bakshi P; Ait-Ghezala G; Mullan M
    Neurosci Lett; 2007 Mar; 415(1):11-6. PubMed ID: 17223266
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein.
    Harris B; Pereira I; Parkin E
    Brain Res; 2009 Nov; 1296():203-15. PubMed ID: 19679113
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Recent advances in Alzheimer's disease research--amyloid precursor protein trafficking, processing, and mutations in Alzheimer's disease linked genes].
    Fukatsu R; Tsuzuki K; Hayashi Y; Takamaru Y; Sasaki N; Yoshida T; Hatakeyama Y; Fuji N; Takahata N
    Hokkaido Igaku Zasshi; 1997 Jan; 72(1):3-11. PubMed ID: 9086357
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Purification and characterization of a novel metalloprotease from human brain with the ability to cleave substrates derived from the N-terminus of beta-amyloid protein.
    Schönlein C; Löffler J; Huber G
    Biochem Biophys Res Commun; 1994 May; 201(1):45-53. PubMed ID: 8198608
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.
    Farzan M; Schnitzler CE; Vasilieva N; Leung D; Choe H
    Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9712-7. PubMed ID: 10931940
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Possible role of calpain in normal processing of beta-amyloid precursor protein in human platelets.
    Chen M; Durr J; Fernandez HL
    Biochem Biophys Res Commun; 2000 Jun; 273(1):170-5. PubMed ID: 10873581
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.