BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 8995312)

  • 1. Amino acid substitutions that convert the protein substrate specificity of farnesyltransferase to that of geranylgeranyltransferase type I.
    Del Villar K; Mitsuzawa H; Yang W; Sattler I; Tamanoi F
    J Biol Chem; 1997 Jan; 272(1):680-7. PubMed ID: 8995312
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic evidence for in vivo cross-specificity of the CaaX-box protein prenyltransferases farnesyltransferase and geranylgeranyltransferase-I in Saccharomyces cerevisiae.
    Trueblood CE; Ohya Y; Rine J
    Mol Cell Biol; 1993 Jul; 13(7):4260-75. PubMed ID: 8321228
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amino acid residues that define both the isoprenoid and CAAX preferences of the Saccharomyces cerevisiae protein farnesyltransferase. Creating the perfect farnesyltransferase.
    Caplin BE; Ohya Y; Marshall MS
    J Biol Chem; 1998 Apr; 273(16):9472-9. PubMed ID: 9545274
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sequence dependence of protein isoprenylation.
    Moores SL; Schaber MD; Mosser SD; Rands E; O'Hara MB; Garsky VM; Marshall MS; Pompliano DL; Gibbs JB
    J Biol Chem; 1991 Aug; 266(22):14603-10. PubMed ID: 1860864
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural homology among mammalian and Saccharomyces cerevisiae isoprenyl-protein transferases.
    Kohl NE; Diehl RE; Schaber MD; Rands E; Soderman DD; He B; Moores SL; Pompliano DL; Ferro-Novick S; Powers S
    J Biol Chem; 1991 Oct; 266(28):18884-8. PubMed ID: 1918005
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Purified yeast protein farnesyltransferase is structurally and functionally similar to its mammalian counterpart.
    Gomez R; Goodman LE; Tripathy SK; O'Rourke E; Manne V; Tamanoi F
    Biochem J; 1993 Jan; 289 ( Pt 1)(Pt 1):25-31. PubMed ID: 8424764
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutant farnesyltransferase beta subunit of Saccharomyces cerevisiae that can substitute for geranylgeranyltransferase type I beta subunit.
    Mitsuzawa H; Esson K; Tamanoi F
    Proc Natl Acad Sci U S A; 1995 Feb; 92(5):1704-8. PubMed ID: 7878044
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: cleavage of the common alpha subunit during apoptosis.
    Kim KW; Chung HH; Chung CW; Kim IK; Miura M; Wang S; Zhu H; Moon KD; Rha GB; Park JH; Jo DG; Woo HN; Song YH; Kim BJ; Yuan J; Jung YK
    Oncogene; 2001 Jan; 20(3):358-66. PubMed ID: 11313965
    [TBL] [Abstract][Full Text] [Related]  

  • 9. cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I.
    Zhang FL; Diehl RE; Kohl NE; Gibbs JB; Giros B; Casey PJ; Omer CA
    J Biol Chem; 1994 Feb; 269(5):3175-80. PubMed ID: 8106351
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Substrate characterization of the Saccharomyces cerevisiae protein farnesyltransferase and type-I protein geranylgeranyltransferase.
    Caplin BE; Hettich LA; Marshall MS
    Biochim Biophys Acta; 1994 Mar; 1205(1):39-48. PubMed ID: 8142482
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Influence of metal ions on substrate binding and catalytic activity of mammalian protein geranylgeranyltransferase type-I.
    Zhang FL; Casey PJ
    Biochem J; 1996 Dec; 320 ( Pt 3)(Pt 3):925-32. PubMed ID: 9003382
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product.
    Finegold AA; Johnson DI; Farnsworth CC; Gelb MH; Judd SR; Glomset JA; Tamanoi F
    Proc Natl Acad Sci U S A; 1991 May; 88(10):4448-52. PubMed ID: 2034682
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Geranylgeranyltransferase I of Candida albicans: null mutants or enzyme inhibitors produce unexpected phenotypes.
    Kelly R; Card D; Register E; Mazur P; Kelly T; Tanaka KI; Onishi J; Williamson JM; Fan H; Satoh T; Kurtz M
    J Bacteriol; 2000 Feb; 182(3):704-13. PubMed ID: 10633104
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
    Terry KL; Casey PJ; Beese LS
    Biochemistry; 2006 Aug; 45(32):9746-55. PubMed ID: 16893176
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CDC43 and RAM2 encode the polypeptide subunits of a yeast type I protein geranylgeranyltransferase.
    Mayer ML; Caplin BE; Marshall MS
    J Biol Chem; 1992 Oct; 267(29):20589-93. PubMed ID: 1400380
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppression of yeast geranylgeranyl transferase I defect by alternative prenylation of two target GTPases, Rho1p and Cdc42p.
    Ohya Y; Qadota H; Anraku Y; Pringle JR; Botstein D
    Mol Biol Cell; 1993 Oct; 4(10):1017-25. PubMed ID: 8298188
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeted reengineering of protein geranylgeranyltransferase type I selectivity functionally implicates active-site residues in protein-substrate recognition.
    Gangopadhyay SA; Losito EL; Hougland JL
    Biochemistry; 2014 Jan; 53(2):434-46. PubMed ID: 24344934
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Site-directed mutations altering the CAAX box of Ste18, the yeast pheromone-response pathway G gamma subunit.
    Whiteway MS; Thomas DY
    Genetics; 1994 Aug; 137(4):967-76. PubMed ID: 7982577
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Yeast farnesyl-diphosphate synthase: site-directed mutagenesis of residues in highly conserved prenyltransferase domains I and II.
    Song L; Poulter CD
    Proc Natl Acad Sci U S A; 1994 Apr; 91(8):3044-8. PubMed ID: 8159703
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Substrate specificity determinants in the farnesyltransferase beta-subunit.
    Trueblood CE; Boyartchuk VL; Rine J
    Proc Natl Acad Sci U S A; 1997 Sep; 94(20):10774-9. PubMed ID: 9380709
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.