BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

100 related articles for article (PubMed ID: 8995517)

  • 1. The tissue distribution in BALB/c mice of C-14-labeled JM216, an orally active platinum antitumour compound.
    Bates PI; Sharma HL; Murrer BA; McAuliffe CA
    Cancer Chemother Pharmacol; 1996; 39(1-2):170-5. PubMed ID: 8995517
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Preclinical toxicology and tissue platinum distribution of novel oral antitumour platinum complexes: ammine/amine platinum(IV) dicarboxylates.
    McKeage MJ; Morgan SE; Boxall FE; Murrer BA; Hard GC; Harrap KR
    Cancer Chemother Pharmacol; 1994; 33(6):497-503. PubMed ID: 8137461
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolism, protein binding and in vivo activity of the oral platinum drug JM216 and its biotransformation products.
    Raynaud FI; Boxall FE; Goddard P; Barnard CF; Murrer BA; Kelland LR
    Anticancer Res; 1996; 16(4A):1857-62. PubMed ID: 8712713
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The synthesis of 191Pt labelled JM216, an orally active platinum anti-tumour agent.
    Bates PI; Sharma HL; Murrer BA; Bernard CF; McAuliffe CA
    Appl Radiat Isot; 1997 Apr; 48(4):469-76. PubMed ID: 9106988
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacokinetics of satraplatin (JM216), an oral platinum (IV) complex under daily oral administration for 5 or 14 days.
    Vouillamoz-Lorenz S; Buclin T; Lejeune F; Bauer J; Leyvraz S; Decosterd LA
    Anticancer Res; 2003; 23(3C):2757-65. PubMed ID: 12926110
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Schedule dependency of orally administered bis-acetato-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) in vivo.
    McKeage MJ; Kelland LR; Boxall FE; Valenti MR; Jones M; Goddard PM; Gwynne J; Harrap KR
    Cancer Res; 1994 Aug; 54(15):4118-22. PubMed ID: 8033145
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biotransformation of the platinum drug JM216 following oral administration to cancer patients.
    Raynaud FI; Mistry P; Donaghue A; Poon GK; Kelland LR; Barnard CF; Murrer BA; Harrap KR
    Cancer Chemother Pharmacol; 1996; 38(2):155-62. PubMed ID: 8616906
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transport of cisplatin and bis-acetato-ammine-dichlorocyclohexylamine Platinum(IV) (JM216) in human ovarian carcinoma cell lines: identification of a plasma membrane protein associated with cisplatin resistance.
    Sharp SY; Rogers PM; Kelland LR
    Clin Cancer Res; 1995 Sep; 1(9):981-9. PubMed ID: 9816070
    [TBL] [Abstract][Full Text] [Related]  

  • 9. cis-Amminedichloro(2-methylpyridine) platinum(II) (AMD473), a novel sterically hindered platinum complex: in vivo activity, toxicology, and pharmacokinetics in mice.
    Raynaud FI; Boxall FE; Goddard PM; Valenti M; Jones M; Murrer BA; Abrams M; Kelland LR
    Clin Cancer Res; 1997 Nov; 3(11):2063-74. PubMed ID: 9815598
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Intracellular metabolism of the orally active platinum drug JM216: influence of glutathione levels.
    Raynaud FI; Odell DE; Kelland LR
    Br J Cancer; 1996 Aug; 74(3):380-6. PubMed ID: 8695352
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinetics of tissue disposition of cis-ammine/cyclohexylamine-dichloroplatinum(II) and cisplatin in mice bearing FSaIIC tumors.
    Yoshida M; Khokhar AR; Zhang YP; Thai G; Siddik ZH
    Cancer Chemother Pharmacol; 1994; 35(1):38-44. PubMed ID: 7987975
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacokinetic and pharmacodynamic analysis of bis-acetato-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) administered once a day for five consecutive days: a phase I study.
    Kurata T; Tamura T; Sasaki Y; Fujii H; Negoro S; Fukuoka M; Saijo N
    Jpn J Clin Oncol; 2000 Sep; 30(9):377-84. PubMed ID: 11095134
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanisms of acquired resistance to the orally active platinum-based anticancer drug bis-acetato-ammine-dichloro-cyclohexylamine platinum (i.v.) (JM216) in two human ovarian carcinoma cell lines.
    Mellish KJ; Kelland LR
    Cancer Res; 1994 Dec; 54(23):6194-200. PubMed ID: 7954466
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Validation of an AAS method for the determination of platinum in biological fluids from patients receiving the oral platinum derivative JM216.
    Vouillamoz-Lorenz S; Bauer J; Lejeune F; Decosterd LA
    J Pharm Biomed Anal; 2001 Jun; 25(3-4):465-75. PubMed ID: 11377026
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic studies of an orally active platinum anticancer drug by liquid chromatography-electrospray ionization mass spectrometry.
    Poon GK; Raynaud FI; Mistry P; Odell DE; Kelland LR; Harrap KR; Barnard CF; Murrer BA
    J Chromatogr A; 1995 Sep; 712(1):61-6. PubMed ID: 8556156
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): an orally active platinum drug.
    Kelland LR; Abel G; McKeage MJ; Jones M; Goddard PM; Valenti M; Murrer BA; Harrap KR
    Cancer Res; 1993 Jun; 53(11):2581-6. PubMed ID: 8388318
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro platinum drug chemosensitivity of human cervical squamous cell carcinoma cell lines with intrinsic and acquired resistance to cisplatin.
    Mellish KJ; Kelland LR; Harrap KR
    Br J Cancer; 1993 Aug; 68(2):240-50. PubMed ID: 8347478
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Preclinical antitumor activity of orally administered platinum (IV) complexes.
    Rose WC; Crosswell AR; Schurig JE; Casazza AM
    Cancer Chemother Pharmacol; 1993; 32(3):197-203. PubMed ID: 8500224
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and in vitro and in vivo antitumor activity of a series of trans platinum antitumor complexes.
    Kelland LR; Barnard CF; Evans IG; Murrer BA; Theobald BR; Wyer SB; Goddard PM; Jones M; Valenti M; Bryant A
    J Med Chem; 1995 Aug; 38(16):3016-24. PubMed ID: 7636864
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Binding properties of an orally active platinum anti-tumor drug JM216 with metallothionein in vivo.
    Xing B; Zhu H; Wang Y; Tang W
    Biometals; 2000 Sep; 13(3):203-8. PubMed ID: 11127891
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.