These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
8. Crystal structure of human DT-diaphorase: a model for interaction with the cytotoxic prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954). Skelly JV; Sanderson MR; Suter DA; Baumann U; Read MA; Gregory DS; Bennett M; Hobbs SM; Neidle S J Med Chem; 1999 Oct; 42(21):4325-30. PubMed ID: 10543876 [TBL] [Abstract][Full Text] [Related]
9. Site-directed mutagenesis of rat liver NAD(P)H: quinone oxidoreductase: roles of lysine 76 and cysteine 179. Ma Q; Cui K; Wang RW; Lu AY; Yang CS Arch Biochem Biophys; 1992 May; 294(2):434-9. PubMed ID: 1567199 [TBL] [Abstract][Full Text] [Related]
10. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase. Fourie J; Oleschuk CJ; Guziec F; Guziec L; Fiterman DJ; Monterrosa C; Begleiter A Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423 [TBL] [Abstract][Full Text] [Related]
11. The differences in kinetics of rat and human DT diaphorase result in a differential sensitivity of derived cell lines to CB 1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). Boland MP; Knox RJ; Roberts JJ Biochem Pharmacol; 1991 Mar 15-Apr 1; 41(6-7):867-75. PubMed ID: 1901207 [TBL] [Abstract][Full Text] [Related]
12. Identification of novel reduced pyridinium derivatives as synthetic co-factors for the enzyme DT diaphorase (NAD(P)H dehydrogenase (quinone), EC 1.6.99.2). Friedlos F; Jarman M; Davies LC; Boland MP; Knox RJ Biochem Pharmacol; 1992 Jul; 44(1):25-31. PubMed ID: 1385952 [TBL] [Abstract][Full Text] [Related]
13. Advances in research on DT-diaphorase--catalytic properties, regulation of activity and significance in the detoxication of foreign compounds. Horie S Kitasato Arch Exp Med; 1990 Apr; 63(1):11-30. PubMed ID: 2125671 [TBL] [Abstract][Full Text] [Related]
14. Expression of rat liver NAD(P)H:quinone-acceptor oxidoreductase in Escherichia coli and mutagenesis in vitro at Arg-177. Chen HH; Ma JX; Forrest GL; Deng PS; Martino PA; Lee TD; Chen S Biochem J; 1992 Jun; 284 ( Pt 3)(Pt 3):855-60. PubMed ID: 1622401 [TBL] [Abstract][Full Text] [Related]
15. Reductase enzyme expression across the National Cancer Institute Tumor cell line panel: correlation with sensitivity to mitomycin C and EO9. Fitzsimmons SA; Workman P; Grever M; Paull K; Camalier R; Lewis AD J Natl Cancer Inst; 1996 Mar; 88(5):259-69. PubMed ID: 8614004 [TBL] [Abstract][Full Text] [Related]
16. The bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954)--II. A comparison of an Escherichia coli nitroreductase and Walker DT diaphorase. Knox RJ; Friedlos F; Sherwood RF; Melton RG; Anlezark GM Biochem Pharmacol; 1992 Dec; 44(12):2297-301. PubMed ID: 1472095 [TBL] [Abstract][Full Text] [Related]
17. Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy. Stiborová M; Frei E; Sopko B; Wiessler M; Schmeiser HH Carcinogenesis; 2002 Apr; 23(4):617-25. PubMed ID: 11960915 [TBL] [Abstract][Full Text] [Related]
18. Gene targeting of DT-diaphorase in mouse embryonic stem cells: establishment of null mutant and its mitomycin C-resistance. Yoshida T; Tsuda H Biochem Biophys Res Commun; 1995 Sep; 214(2):701-8. PubMed ID: 7677784 [TBL] [Abstract][Full Text] [Related]
19. Nitrobenzimidazoles as substrates for DT-diaphorase and redox cycling compounds: their enzymatic reactions and cytotoxicity. Sarlauskas J; Dickancaite E; Nemeikaite A; Anusevicius Z; Nivinskas H; Segura-Aguilar J; Cenas N Arch Biochem Biophys; 1997 Oct; 346(2):219-29. PubMed ID: 9343369 [TBL] [Abstract][Full Text] [Related]