BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 8999846)

  • 1. Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells.
    Lavie Y; Cao Ht; Volner A; Lucci A; Han TY; Geffen V; Giuliano AE; Cabot MC
    J Biol Chem; 1997 Jan; 272(3):1682-7. PubMed ID: 8999846
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance.
    Liu YY; Han TY; Giuliano AE; Hansen N; Cabot MC
    J Biol Chem; 2000 Mar; 275(10):7138-43. PubMed ID: 10702281
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug-resistant cancer cells.
    Lucci A; Han TY; Liu YY; Giuliano AE; Cabot MC
    Cancer; 1999 Jul; 86(2):300-11. PubMed ID: 10421266
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells.
    Liu YY; Han TY; Giuliano AE; Cabot MC
    J Biol Chem; 1999 Jan; 274(2):1140-6. PubMed ID: 9873062
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ceramide glycosylation potentiates cellular multidrug resistance.
    Liu YY; Han TY; Giuliano AE; Cabot MC
    FASEB J; 2001 Mar; 15(3):719-30. PubMed ID: 11259390
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modification of ceramide metabolism increases cancer cell sensitivity to cytotoxics.
    Lucci A; Han TY; Liu YY; Giuliano AE; Cabot MC
    Int J Oncol; 1999 Sep; 15(3):541-6. PubMed ID: 10427137
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ceramide toxicity and metabolism differ in wild-type and multidrug-resistant cancer cells.
    Lucci A; Giuliano AE; Han TY; Dinur T; Liu YY; Senchenkov A; Cabot MC
    Int J Oncol; 1999 Sep; 15(3):535-40. PubMed ID: 10427136
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting glucosylceramide synthase induction of cell surface globotriaosylceramide (Gb3) in acquired cisplatin-resistance of lung cancer and malignant pleural mesothelioma cells.
    Tyler A; Johansson A; Karlsson T; Gudey SK; Brännström T; Grankvist K; Behnam-Motlagh P
    Exp Cell Res; 2015 Aug; 336(1):23-32. PubMed ID: 26004871
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Accumulation of glucosylceramides in multidrug-resistant cancer cells.
    Lavie Y; Cao H; Bursten SL; Giuliano AE; Cabot MC
    J Biol Chem; 1996 Aug; 271(32):19530-6. PubMed ID: 8702646
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combined use of tamoxifen, cyclosporin A, and verapamil for modulating multidrug resistance in human hepatocellular carcinoma cell lines.
    Kim JH; Chung JB; Park IS; Kim BS; Yoo NC; Choi JH; Roh JK; Kim HS; Kwon OH; Lee KS
    Yonsei Med J; 1993 Mar; 34(1):35-44. PubMed ID: 8397460
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression of P-glycoprotein in HeLa cells confers resistance to ceramide cytotoxicity.
    Chapman JV; Gouazé-Andersson V; Cabot MC
    Int J Oncol; 2010 Dec; 37(6):1591-7. PubMed ID: 21042729
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy.
    Gouazé V; Yu JY; Bleicher RJ; Han TY; Liu YY; Wang H; Gottesman MM; Bitterman A; Giuliano AE; Cabot MC
    Mol Cancer Ther; 2004 May; 3(5):633-9. PubMed ID: 15141021
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tamoxifen retards glycosphingolipid metabolism in human cancer cells.
    Cabot MC; Giuliano AE; Volner A; Han TY
    FEBS Lett; 1996 Sep; 394(2):129-31. PubMed ID: 8843149
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs.
    Gouazé V; Liu YY; Prickett CS; Yu JY; Giuliano AE; Cabot MC
    Cancer Res; 2005 May; 65(9):3861-7. PubMed ID: 15867385
    [TBL] [Abstract][Full Text] [Related]  

  • 15. P-glycoprotein modulates ceramide-mediated sensitivity of human breast cancer cells to tubulin-binding anticancer drugs.
    Shabbits JA; Mayer LD
    Mol Cancer Ther; 2002 Jan; 1(3):205-13. PubMed ID: 12467215
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells.
    Liu YY; Han TY; Yu JY; Bitterman A; Le A; Giuliano AE; Cabot MC
    J Lipid Res; 2004 May; 45(5):933-40. PubMed ID: 14967819
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulatory effect of tamoxifen and ICI 182,780 on adriamycin resistance in MCF-7 human breast-cancer cells.
    De Vincenzo R; Scambia G; Benedetti Panici P; Fattorossi A; Bonanno G; Ferlini C; Isola G; Pernisco S; Mancuso S
    Int J Cancer; 1996 Nov; 68(3):340-8. PubMed ID: 8903476
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of glucosylceramide synthase does not reverse drug resistance in cancer cells.
    Norris-Cervetto E; Callaghan R; Platt FM; Dwek RA; Butters TD
    J Biol Chem; 2004 Sep; 279(39):40412-8. PubMed ID: 15263008
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reversal effects of nomegestrol acetate on multidrug resistance in adriamycin-resistant MCF7 breast cancer cell line.
    Li J; Xu LZ; He KL; Guo WJ; Zheng YH; Xia P; Chen Y
    Breast Cancer Res; 2001; 3(4):253-63. PubMed ID: 11434876
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of glycosphingolipid biosynthesis reverts multidrug resistance by differentially modulating ABC transporters in chronic myeloid leukemias.
    Salustiano EJ; da Costa KM; Freire-de-Lima L; Mendonça-Previato L; Previato JO
    J Biol Chem; 2020 May; 295(19):6457-6471. PubMed ID: 32229586
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.