68 related articles for article (PubMed ID: 9010639)
1. In vitro and in vivo disposition of 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide (CI-976). Identification of a novel five-carbon cleavage metabolite in rats.
Sinz MW; Black AE; Bjorge SM; Holmes A; Trivedi BK; Woolf TF
Drug Metab Dispos; 1997 Jan; 25(1):123-30. PubMed ID: 9010639
[TBL] [Abstract][Full Text] [Related]
2. Metabolism of the acyl-CoA:cholesterol acyltransferase inhibitor 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide in rat and monkey. Omega-/beta-oxidation pathway.
Woolf TF; Bjorge SM; Black AE; Holmes A; Chang T
Drug Metab Dispos; 1991; 19(3):696-702. PubMed ID: 1680639
[TBL] [Abstract][Full Text] [Related]
3. Biodisposition studies with the acyl-coenzyme A: cholesterol acyltransferase inhibitor 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide, CI-976.
Woolf TF; Black A; Shum YY; McNally W; Lee H; Chang T
Drug Metab Dispos; 1993; 21(6):1112-8. PubMed ID: 7905392
[TBL] [Abstract][Full Text] [Related]
4. Metabolism of sameridine to monocarboxylated products by hepatocytes isolated from the male rat.
Sohlenius-Sternbeck AK; Chelpin HV; Orzechowski A; Halldin MM
Drug Metab Dispos; 2000 Jun; 28(6):695-700. PubMed ID: 10820143
[TBL] [Abstract][Full Text] [Related]
5. In vitro hydroxylation and epoxidation of some isomeric lauric acid analogs by rat liver microsomes. Identification of metabolites and effects of clofibrate or phenobarbital pretreatment.
Boucher JL; Delaforge M; Salaün JP; Pinot F; Durst F; Pflieger P; Mioskowski C
Drug Metab Dispos; 1996 Apr; 24(4):462-8. PubMed ID: 8801062
[TBL] [Abstract][Full Text] [Related]
6. Metabolism and excretion studies in mouse after single and multiple oral doses of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin.
Black AE; Sinz MW; Hayes RN; Woolf TF
Drug Metab Dispos; 1998 Aug; 26(8):755-63. PubMed ID: 9698289
[TBL] [Abstract][Full Text] [Related]
7. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
Beland FA
Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
[TBL] [Abstract][Full Text] [Related]
8. CYP2C8- and CYP3A-mediated C-demethylation of (3-{[(4-tert-butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid (CP-533,536), an EP2 receptor-selective prostaglandin E2 agonist: characterization of metabolites by high-resolution liquid chromatography-tandem mass spectrometry and liquid chromatography/mass spectrometry-nuclear magnetic resonance.
Prakash C; Wang W; O'Connell T; Johnson KA
Drug Metab Dispos; 2008 Oct; 36(10):2093-103. PubMed ID: 18653741
[TBL] [Abstract][Full Text] [Related]
9. In vitro metabolism of rivaroxaban, an oral, direct factor Xa inhibitor, in liver microsomes and hepatocytes of rats, dogs, and humans.
Lang D; Freudenberger C; Weinz C
Drug Metab Dispos; 2009 May; 37(5):1046-55. PubMed ID: 19196846
[TBL] [Abstract][Full Text] [Related]
10. Cytochrome P450 inactivation during reductive metabolism of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) by phenobarbital- and pyridine-induced rat liver microsomes.
Ferrara R; Tolando R; King LJ; Manno M
Toxicol Appl Pharmacol; 1997 Apr; 143(2):420-8. PubMed ID: 9144458
[TBL] [Abstract][Full Text] [Related]
11. CYP2D6-Mediated metabolism of a novel acyl coenzyme A:cholesterol acyltransferase inhibitor, pactimibe, and its unique plasma metabolite, R-125528.
Kotsuma M; Tokui T; Ishizuka-Ozeki T; Honda T; Iwabuchi H; Murai T; Ikeda T; Saji H
Drug Metab Dispos; 2008 Mar; 36(3):529-34. PubMed ID: 18056254
[TBL] [Abstract][Full Text] [Related]
12. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
Kalgutkar AS; Hatch HL; Kosea F; Nguyen HT; Choo EF; McClure KF; Taylor TJ; Henne KR; Kuperman AV; Dombroski MA; Letavic MA
Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451
[TBL] [Abstract][Full Text] [Related]
13. 3-ketocholanoic acid is the major in vitro human hepatic microsomal metabolite of lithocholic acid.
Deo AK; Bandiera SM
Drug Metab Dispos; 2009 Sep; 37(9):1938-47. PubMed ID: 19487251
[TBL] [Abstract][Full Text] [Related]
14. CYP4 isoform specificity in the omega-hydroxylation of phytanic acid, a potential route to elimination of the causative agent of Refsum's disease.
Xu F; Ng VY; Kroetz DL; de Montellano PR
J Pharmacol Exp Ther; 2006 Aug; 318(2):835-9. PubMed ID: 16707724
[TBL] [Abstract][Full Text] [Related]
15. beta-Oxidation of simvastatin in mouse liver preparations.
Prueksaritanont T; Ma B; Fang X; Subramanian R; Yu J; Lin JH
Drug Metab Dispos; 2001 Oct; 29(10):1251-5. PubMed ID: 11560866
[TBL] [Abstract][Full Text] [Related]
16. [Biotransformation of the lipoxygenase inhibitor 2-hydroxy-5-methyl-laurophenone-oxime (FLM 5011)].
Langner A; Rentsch C; Nerlich C; Rittner I; Kühn H; Schewe T; Franke P
Pharmazie; 1996 Jun; 51(6):403-9. PubMed ID: 8767850
[TBL] [Abstract][Full Text] [Related]
17. Role of C-5 chiral center in R-(+)-pulegone-mediated hepatotoxicity: metabolic disposition and toxicity of 5, 5-dimethyl-2-(1-Methylethylidene)-cyclohexanone in rats.
Thulasiram HV; Gadad AK; Madyastha MK
Drug Metab Dispos; 2000 Jul; 28(7):833-44. PubMed ID: 10859158
[TBL] [Abstract][Full Text] [Related]
18. Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites.
Remmel RP; Crews BC; Kozak KR; Kalgutkar AS; Marnett LJ
Drug Metab Dispos; 2004 Jan; 32(1):113-22. PubMed ID: 14709628
[TBL] [Abstract][Full Text] [Related]
19. Use of acyltransferase inhibitors to block vesicular traffic between the ER and Golgi complex.
Brown WJ; Schmidt JA
Methods Enzymol; 2005; 404():115-25. PubMed ID: 16413263
[TBL] [Abstract][Full Text] [Related]
20. Oxidative cleavage of the octyl side chain of 1-(3,4-dichlorobenzyl)-5-octylbiguanide (OPB-2045) in rat and dog liver preparations.
Umehara K; Kudo S; Hirao Y; Morita S; Uchida M; Odomi M; Miyamoto G
Drug Metab Dispos; 2000 Aug; 28(8):887-94. PubMed ID: 10901696
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
