BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

256 related articles for article (PubMed ID: 9012414)

  • 1. Homopolymeric tract heteroplasmy in mtDNA from tissues and single oocytes: support for a genetic bottleneck.
    Marchington DR; Hartshorne GM; Barlow D; Poulton J
    Am J Hum Genet; 1997 Feb; 60(2):408-16. PubMed ID: 9012414
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evidence from human oocytes for a genetic bottleneck in an mtDNA disease.
    Marchington DR; Macaulay V; Hartshorne GM; Barlow D; Poulton J
    Am J Hum Genet; 1998 Sep; 63(3):769-75. PubMed ID: 9718339
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prospects for DNA-based prenatal diagnosis of mitochondrial disorders.
    Poulton J; Marchington DR
    Prenat Diagn; 1996 Dec; 16(13):1247-56. PubMed ID: 9061755
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intracellular heteroplasmy for disease-associated point mutations in mtDNA: implications for disease expression and evidence for mitotic segregation of heteroplasmic units of mtDNA.
    Matthews PM; Brown RM; Morten K; Marchington D; Poulton J; Brown G
    Hum Genet; 1995 Sep; 96(3):261-8. PubMed ID: 7649539
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A systematic analysis of the suitability of preimplantation genetic diagnosis for mitochondrial diseases in a heteroplasmic mitochondrial mouse model.
    Neupane J; Vandewoestyne M; Heindryckx B; Ghimire S; Lu Y; Qian C; Lierman S; Van Coster R; Gerris J; Deroo T; Deforce D; De Sutter P
    Hum Reprod; 2014 Apr; 29(4):852-9. PubMed ID: 24524987
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes.
    Cree LM; Samuels DC; de Sousa Lopes SC; Rajasimha HK; Wonnapinij P; Mann JR; Dahl HH; Chinnery PF
    Nat Genet; 2008 Feb; 40(2):249-54. PubMed ID: 18223651
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Information for genetic management of mtDNA disease: sampling pathogenic mtDNA mutants in the human germline and in placenta.
    Marchington D; Malik S; Banerjee A; Turner K; Samuels D; Macaulay V; Oakeshott P; Fratter C; Kennedy S; Poulton J
    J Med Genet; 2010 Apr; 47(4):257-61. PubMed ID: 19914907
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deep sequencing shows that oocytes are not prone to accumulate mtDNA heteroplasmic mutations during ovarian ageing.
    Boucret L; Bris C; Seegers V; Goudenège D; Desquiret-Dumas V; Domin-Bernhard M; Ferré-L'Hotellier V; Bouet PE; Descamps P; Reynier P; Procaccio V; May-Panloup P
    Hum Reprod; 2017 Oct; 32(10):2101-2109. PubMed ID: 28938736
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors.
    Sanchez-Cespedes M; Parrella P; Nomoto S; Cohen D; Xiao Y; Esteller M; Jeronimo C; Jordan RC; Nicol T; Koch WM; Schoenberg M; Mazzarelli P; Fazio VM; Sidransky D
    Cancer Res; 2001 Oct; 61(19):7015-9. PubMed ID: 11585726
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutation-specific effects in germline transmission of pathogenic mtDNA variants.
    Otten ABC; Sallevelt SCEH; Carling PJ; Dreesen JCFM; Drüsedau M; Spierts S; Paulussen ADC; de Die-Smulders CEM; Herbert M; Chinnery PF; Samuels DC; Lindsey P; Smeets HJM
    Hum Reprod; 2018 Jul; 33(7):1331-1341. PubMed ID: 29850888
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Skewed segregation of the mtDNA nt 8993 (T-->G) mutation in human oocytes.
    Blok RB; Gook DA; Thorburn DR; Dahl HH
    Am J Hum Genet; 1997 Jun; 60(6):1495-501. PubMed ID: 9199572
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitochondrial DNA heteroplasmy in ovine fetuses and sheep cloned by somatic cell nuclear transfer.
    Burgstaller JP; Schinogl P; Dinnyes A; Müller M; Steinborn R
    BMC Dev Biol; 2007 Dec; 7():141. PubMed ID: 18154666
    [TBL] [Abstract][Full Text] [Related]  

  • 13. mtDNA point mutations are present at various levels of heteroplasmy in human oocytes.
    Jacobs L; Gerards M; Chinnery P; Dumoulin J; de Coo I; Geraedts J; Smeets H
    Mol Hum Reprod; 2007 Mar; 13(3):149-54. PubMed ID: 17259224
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Heteroplasmy in human mtDNA control region].
    Cao Y; Wan LH; Gu LG; Huang YX; Xiu CX; Hu SH; Mi C
    Fa Yi Xue Za Zhi; 2006 Jun; 22(3):190-2. PubMed ID: 16856340
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Quantitative haplotype-resolved analysis of mitochondrial DNA heteroplasmy in Human single oocytes, blastoids, and pluripotent stem cells.
    Bi C; Wang L; Fan Y; Yuan B; Alsolami S; Zhang Y; Zhang PY; Huang Y; Yu Y; Izpisua Belmonte JC; Li M
    Nucleic Acids Res; 2023 May; 51(8):3793-3805. PubMed ID: 37014011
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes.
    Wai T; Teoli D; Shoubridge EA
    Nat Genet; 2008 Dec; 40(12):1484-8. PubMed ID: 19029901
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lack of Structural Variation but Extensive Length Polymorphisms and Heteroplasmic Length Variations in the Mitochondrial DNA Control Region of Highly Inbred Crested Ibis, Nipponia nippon.
    He XL; Ding CQ; Han JL
    PLoS One; 2013; 8(6):e66324. PubMed ID: 23805212
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [The correlation of the heteroplasmy of mtDNA and clinicopathological findings in the patients with mitochondrial encephalomyopathies].
    Tanno Y; Tanaka K; Tsuji S
    Nihon Rinsho; 1997 Dec; 55(12):3270-6. PubMed ID: 9436449
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Analysis of a polycytosine tract and heteroplasmic length variation in the mitochondrial DNA D-loop of patients with diabetes, MELAS syndrome and race-matched controls.
    Gill-Randall R; Sherratt EJ; Thomas AW; Gagg JW; Lee A; Alcolado JC
    Diabet Med; 2001 May; 18(5):413-6. PubMed ID: 11472454
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A wide range of 3243A>G/tRNALeu(UUR) (MELAS) mutation loads may segregate in offspring through the female germline bottleneck.
    Pallotti F; Binelli G; Fabbri R; Valentino ML; Vicenti R; Macciocca M; Cevoli S; Baruzzi A; DiMauro S; Carelli V
    PLoS One; 2014; 9(5):e96663. PubMed ID: 24805791
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.