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2. Pre-clinical development of the anti-tumour agent CB 7646, bis N-(hydroxymethyl) trimethylmelamine, a stable analogue of trimelamol. Coley HM; Jarman M; Brooks N; Kubota T; Goddard PM; Jones M; Lee N; Owens MD; Halbert GW; Judson IR Int J Cancer; 1996 Nov; 68(3):356-63. PubMed ID: 8903478 [TBL] [Abstract][Full Text] [Related]
3. The activity of N-(hydroxymethyl) melamines in fresh human ovarian tumour cells and xenografts. Coley HM; Jarman M; Jones M; Sargent JM; Kubota T; Lee NC; Goddard PM; Elgie AW; Williamson C; Taylor CG; Judson IR Anticancer Res; 1996; 16(4A):1851-5. PubMed ID: 8712712 [TBL] [Abstract][Full Text] [Related]
4. Preclinical toxicology, pharmacokinetics and formulation of N2,N4,N6-trihydroxymethyl-N2,N4,N6-trimethylmelamine (trimelamol), a water-soluble cytotoxic s-triazine which does not require metabolic activation. Rutty CJ; Judson IR; Abel G; Goddard PM; Newell DR; Harrap KR Cancer Chemother Pharmacol; 1986; 17(3):251-8. PubMed ID: 3091280 [TBL] [Abstract][Full Text] [Related]
5. Superior efficacy of trimelamol to hexamethylmelamine in human ovarian cancer xenografts. Boven E; Nauta MM; Schlüper HM; Erkelens CA; Pinedo HM Cancer Chemother Pharmacol; 1986; 18(2):124-8. PubMed ID: 3098444 [TBL] [Abstract][Full Text] [Related]
6. Stable analogues of the antitumour agent trimelamol retain in vitro cytotoxicity in drug-sensitive and resistant rodent and human cell lines. Coley HM; Jarman M; Brooks N; Thornton TJ; Judson IR Eur J Cancer; 1994; 30A(12):1827-36. PubMed ID: 7880614 [TBL] [Abstract][Full Text] [Related]
7. The role of the N-(hydroxymethyl)melamines as antitumour agents: mechanism of action studies. Coley HM; Brooks N; Phillips DH; Hewer A; Jenkins TC; Jarman M; Judson IR Biochem Pharmacol; 1995 May; 49(9):1203-12. PubMed ID: 7763301 [TBL] [Abstract][Full Text] [Related]
8. Phase I trial and pharmacokinetics of trimelamol (N2,N4,N6-trihydroxymethyl-N2,N4,N6-trimethylmelamine). Judson IR; Calvert AH; Rutty CJ; Abel G; Gumbrell LA; Graham MA; Evans BD; Wilman DE; Ashley SE; Cairnduff F Cancer Res; 1989 Oct; 49(19):5475-9. PubMed ID: 2670205 [TBL] [Abstract][Full Text] [Related]
9. Low central nervous system penetration of N2,N4,N6,-trihydroxymethyl-N2,N4,N6,-trimethylmelamine (Trimelamol): a cytotoxic s-triazine with reduced neurotoxicity. Judson IR; Rutty CJ; Abel G; Graham MA Br J Cancer; 1986 May; 53(5):601-6. PubMed ID: 3087399 [TBL] [Abstract][Full Text] [Related]
10. Role of hexamethylmelamine in the treatment of ovarian cancer: where is the needle in the haystack? Foster BJ; Clagett-Carr K; Marsoni S; Simon R; Leyland-Jones B Cancer Treat Rep; 1986 Aug; 70(8):1003-14. PubMed ID: 3089597 [TBL] [Abstract][Full Text] [Related]
11. Altretamine (hexamethylmelamine) in platinum-resistant and platinum-refractory ovarian cancer: a Gynecologic Oncology Group phase II trial. Markman M; Blessing JA; Moore D; Ball H; Lentz SS Gynecol Oncol; 1998 Jun; 69(3):226-9. PubMed ID: 9648592 [TBL] [Abstract][Full Text] [Related]
12. Hexamethylmelamine and pentamethylmelamine tissue distribution in M5076/73A ovarian cancer-bearing mice. Broggini M; Rossi C; Colombo T; D'Incalci M Cancer Treat Rep; 1982 Jan; 66(1):127-33. PubMed ID: 6796267 [TBL] [Abstract][Full Text] [Related]
13. Hexamethylmelamine and pentamethylmelamine: an update. Hahn DA Drug Intell Clin Pharm; 1983 Jun; 17(6):418-24. PubMed ID: 6407810 [TBL] [Abstract][Full Text] [Related]
14. Pentamethylmelamine: review of an aqueous analog of hexamethylmelamine. Foster BJ; Clagett-Carr K; Hoth D; Leyland-Jones B Cancer Treat Rep; 1986 Mar; 70(3):383-9. PubMed ID: 3082512 [TBL] [Abstract][Full Text] [Related]
15. Phase I trial of pentamethylmelamine. Ajani JA; Cabanillas FF; Bodey GP Cancer Treat Rep; 1982 May; 66(5):1227-8. PubMed ID: 6805950 [TBL] [Abstract][Full Text] [Related]
16. Hexamethylmelamine: a critical review of an active drug. Foster BJ; Harding BJ; Leyland-Jones B; Hoth D Cancer Treat Rev; 1986 Dec; 13(4):197-217. PubMed ID: 3102057 [TBL] [Abstract][Full Text] [Related]
17. Preclinical discovery of ixabepilone, a highly active antineoplastic agent. Lee FY; Borzilleri R; Fairchild CR; Kamath A; Smykla R; Kramer R; Vite G Cancer Chemother Pharmacol; 2008 Dec; 63(1):157-66. PubMed ID: 18347795 [TBL] [Abstract][Full Text] [Related]
18. Phase II trial of hexamethylmelamine in ovarian carcinoma resistant to alkylating agents. Bonomi PD; Mladineo J; Morrin B; Wilbanks G; Slayton RE Cancer Treat Rep; 1979 Jan; 63(1):137-8. PubMed ID: 105805 [No Abstract] [Full Text] [Related]
19. Analogues of hexamethylmelamine. The anti-neoplastic activity of derivatives with enhanced water solubility. Cumber AJ; Ross WC Chem Biol Interact; 1977 Jun; 17(3):349-57. PubMed ID: 407012 [TBL] [Abstract][Full Text] [Related]
20. Antitumor activity of hexamethylmelamine on human tumor xenografts serially transplanted in nude mice. Kubota T; Tanino H; Watanabe M; Kitajima M Anticancer Res; 1994; 14(6B):2521-4. PubMed ID: 7872676 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]